Reactome | Mondo:0018997

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Mondo:0018997 Show undefined attributes

databaseName	Mondo
dbId	12020778
displayName	Mondo:0018997
identifier	0018997
referenceDatabase	[ReferenceDatabase:12020742] Mondo
schemaClass	DatabaseIdentifier
url	https://monarchinitiative.org/MONDO:0018997

Referrals

(crossReference)

[EntityWithAccessionedSequence:R-HSA-9660464] SHOC2 Q269_H270delinsHY [cytosol]
[EntityWithAccessionedSequence:R-HSA-9656017] p-S338,Y341,S494,S621 RAF1 T491R [cytosol]
[EntityWithAccessionedSequence:R-HSA-9656145] p-S621-RAF1 T491R [cytosol]
[Pathway:R-HSA-6802949] Signaling by RAS mutants
[BlackBoxEvent:R-HSA-6803240] Homo- or heterodimerization of RAF downstream of mutant RAS
[Reaction:R-HSA-6803233] Dissociation of oncogenic RAS:RAF complex
[FailedReaction:R-HSA-9660536] SHOC2 M173I disrupts the SHOC2:MRAS:PP1 complex
[Pathway:R-HSA-9726840] SHOC2 M1731 mutant abolishes MRAS complex function
[CandidateSet:R-HSA-9656159] p-S621 RAF1 CR2 mutants [cytosol]
[CandidateSet:R-HSA-9656161] p-S621 RAF1 CR3 mutants [cytosol]
[CandidateSet:R-HSA-6802608] RAS GTPase mutants [plasma membrane]
[EntityWithAccessionedSequence:R-HSA-9656098] p-S621-RAF1 L613V [cytosol]
[EntityWithAccessionedSequence:R-HSA-9656035] p-S338,Y341,T492,S494,S621 RAF1 L613V [cytosol]
[Complex:R-HSA-6803238] RAS mutants:GTP:RAF [plasma membrane]
[EntityWithAccessionedSequence:R-HSA-9656053] p-S338,Y341,T492,S494,S621 RAF1 P261T [cytosol]
[EntityWithAccessionedSequence:R-HSA-9656115] p-S621-RAF1 P261T [cytosol]
[EntityWithAccessionedSequence:R-HSA-9656143] p-S621-RAF1 T491I [cytosol]
[EntityWithAccessionedSequence:R-HSA-9656019] p-S338,Y341,S494,S621-RAF1 T491I [cytosol]
[EntityWithAccessionedSequence:R-HSA-9656014] HRAS T58I [plasma membrane]
[EntityWithAccessionedSequence:R-HSA-9656092] p-S621-RAF1 G361A [cytosol]
[EntityWithAccessionedSequence:R-HSA-9656029] p-S338,Y341,T492,S494,S621 RAF1 G361A [cytosol]
[EntityWithAccessionedSequence:R-HSA-9651269] KRAS P34L [plasma membrane]
[EntityWithAccessionedSequence:R-HSA-6802480] KRAS V14I [plasma membrane]
[EntityWithAccessionedSequence:R-HSA-9651367] KRAS Q22R [plasma membrane]
[EntityWithAccessionedSequence:R-HSA-6802292] KRAS D153V [plasma membrane]
[Complex:R-HSA-9660490] SHOC2 M173I:MRAS:PP1 [plasma membrane]
[EntityWithAccessionedSequence:R-HSA-9656085] p-S621-RAF1 D486G [cytosol]
[EntityWithAccessionedSequence:R-HSA-9656130] p-S621-RAF1 S259T [cytosol]
[EntityWithAccessionedSequence:R-HSA-9656023] p-S338,Y341,T492,S494,S621 RAF1 D486G [cytosol]
[EntityWithAccessionedSequence:R-HSA-9656070] p-S338,Y341,T492,S494,S621 RAF1 S427G [cytosol]
[CandidateSet:R-HSA-9660505] mutant MRAS:SHOC2:PP1 complexes [plasma membrane]
[EntityWithAccessionedSequence:R-HSA-6802472] KRAS T58I [plasma membrane]
[EntityWithAccessionedSequence:R-HSA-9656119] p-S621-RAF1 R256S [cytosol]
[EntityWithAccessionedSequence:R-HSA-9660543] PPP1CB A56P [cytosol]
[EntityWithAccessionedSequence:R-HSA-9656026] p-S338,Y341,T492,S494,S621 RAF1 D486N [cytosol]
[EntityWithAccessionedSequence:R-HSA-9656088] p-S621-RAF1 D486N [cytosol]
[EntityWithAccessionedSequence:R-HSA-9660508] S-GGC MRAS G23R [plasma membrane]
[EntityWithAccessionedSequence:R-HSA-9660504] S-GGC MRAS G23V [plasma membrane]
[DefinedSet:R-HSA-9660498] PPP1CB mutants [cytosol]
[EntityWithAccessionedSequence:R-HSA-9651364] KRAS Q22E [plasma membrane]
[EntityWithAccessionedSequence:R-HSA-9656010] HRAS K117R [plasma membrane]
[EntityWithAccessionedSequence:R-HSA-9656008] HRAS G13C [plasma membrane]
[EntityWithAccessionedSequence:R-HSA-9660514] S-GGC MRAS T68I [plasma membrane]
[EntityWithAccessionedSequence:R-HSA-9656134] p-S621-RAF1 S427G [cytosol]
[Complex:R-HSA-9660507] S-GCC MRAS:GTP:SHOC2:PP1 mutants [plasma membrane]
[EntityWithAccessionedSequence:R-HSA-9656056] p-S338,Y341,T492,S494,S621 RAF1 R256S [cytosol]
[EntityWithAccessionedSequence:R-HSA-9660486] SHOC2 M173I [cytosol]
[EntityWithAccessionedSequence:R-HSA-9656067] p-S338,Y341,T492,S494,S621 RAF1 S259T [cytosol]
[EntityWithAccessionedSequence:R-HSA-9651359] KRAS G60R [plasma membrane]
[DefinedSet:R-HSA-9660468] SHOC2 gain-of-function mutants [cytosol]
[EntityWithAccessionedSequence:R-HSA-9660547] PPP1CB P49R [cytosol]

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