Reactome | KRAS D153V [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:6802291] Rothfels, Karen, 2015-10-02
crossReference	[DatabaseIdentifier:12020778] Mondo:0018997 [DatabaseIdentifier:9651330] ClinGen:CA256478
dbId	6802292
disease	[Disease:6802289] Noonan syndrome
displayName	KRAS D153V [plasma membrane]
endCoordinate	186
hasModifiedResidue	[ReplacedResidue:6802290] L-aspartic acid 153 replaced with L-valine
inDisease	true
literatureReference	[LiteratureReference:9651267] Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders
maxDepth	1
memberOf	[CandidateSet:R-HSA-9651281] RAS GAP mutants [plasma membrane] - Homo sapiens [CandidateSet:R-HSA-6802608] RAS GTPase mutants [plasma membrane] - Homo sapiens
modified	[InstanceEdit:9651374] Rothfels, Karen, 2019-06-25
name	KRAS D153V
referenceEntity	[ReferenceGeneProduct:uniprot:P01116] UniProt:P01116 KRAS
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-6802292
startCoordinate	1
updateTrackers	[UpdateTracker:9900820] Update Tracker - [EntityWithAccessionedSequence:6802292] KRAS D153V [plasma membrane] - v70:[addLiteratureReference, modifyName]

(updatedInstance)	[UpdateTracker:9900820] Update Tracker - [EntityWithAccessionedSequence:6802292] KRAS D153V [plasma membrane] - v70:[addLiteratureReference, modifyName]
(hasMember)	[CandidateSet:R-HSA-6802608] RAS GTPase mutants [plasma membrane] [CandidateSet:R-HSA-9651281] RAS GAP mutants [plasma membrane]

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