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p-Y-IRS1,p-Y-IRS2 [cytosol]
Stable Identifier
R-XTR-112322
Type
Set [DefinedSet]
Species
Xenopus tropicalis
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Signal Transduction (Xenopus tropicalis)
MAPK family signaling cascades (Xenopus tropicalis)
MAPK1/MAPK3 signaling (Xenopus tropicalis)
RAF/MAP kinase cascade (Xenopus tropicalis)
RAS GEFs promote RAS nucleotide exchange (Xenopus tropicalis)
RAS GEFs [plasma membrane] (Xenopus tropicalis)
GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2 [cytosol] (Xenopus tropicalis)
Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by Insulin receptor (Xenopus tropicalis)
Insulin receptor signalling cascade (Xenopus tropicalis)
IRS activation (Xenopus tropicalis)
Dissociation of IRS-P from insulin receptor (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2 [cytosol] (Xenopus tropicalis)
p-Y-IRS:Insulin:p-6Y-Insulin receptor [plasma membrane] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2 [cytosol] (Xenopus tropicalis)
Phosphorylation of IRS (Xenopus tropicalis)
p-Y-IRS:Insulin:p-6Y-Insulin receptor [plasma membrane] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2 [cytosol] (Xenopus tropicalis)
IRS-mediated signalling (Xenopus tropicalis)
PI3K Cascade (Xenopus tropicalis)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Xenopus tropicalis)
PI3K-containing complexes [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2 [cytosol] (Xenopus tropicalis)
SOS-mediated signalling (Xenopus tropicalis)
GRB2-1:SOS1 binds p-IRS1,p-IRS2 (Xenopus tropicalis)
GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2 [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2 [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2 bind PI3K (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2 [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2 [cytosol] (Xenopus tropicalis)
Signal attenuation (Xenopus tropicalis)
GRB2:p-4S-SOS1:p-Y-IRS1,p-Y-IRS2 dissociates (Xenopus tropicalis)
GRB2:p-4S-SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2 [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2 [cytosol] (Xenopus tropicalis)
Signaling by NTRKs (Xenopus tropicalis)
Signaling by NTRK1 (TRKA) (Xenopus tropicalis)
PI3K/AKT activation (Xenopus tropicalis)
Active IRS recruits PI3K to the plasma membrane and activates it (Xenopus tropicalis)
Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2 [cytosol] (Xenopus tropicalis)
Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Xenopus tropicalis)
Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2 [cytosol] (Xenopus tropicalis)
PI3K produces PIP3 and other phosphatidyl inositides (Xenopus tropicalis)
Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Xenopus tropicalis)
Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2 [cytosol] (Xenopus tropicalis)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Xenopus tropicalis)
IGF1R signaling cascade (Xenopus tropicalis)
IRS-related events triggered by IGF1R (Xenopus tropicalis)
IRS-mediated signalling (Xenopus tropicalis)
PI3K Cascade (Xenopus tropicalis)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Xenopus tropicalis)
PI3K-containing complexes [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2 [cytosol] (Xenopus tropicalis)
SOS-mediated signalling (Xenopus tropicalis)
GRB2-1:SOS1 binds p-IRS1,p-IRS2 (Xenopus tropicalis)
GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2 [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2 [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2 bind PI3K (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2 [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2 [cytosol] (Xenopus tropicalis)
Participants
members
phospho-irs1 [cytosol]
(Xenopus tropicalis)
phospho-LOC100498409 [cytosol]
(Xenopus tropicalis)
Participates
as an input of
p-Y-IRS1,p-Y-IRS2 bind PI3K (Xenopus tropicalis)
GRB2-1:SOS1 binds p-IRS1,p-IRS2 (Xenopus tropicalis)
as a component of
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Xenopus tropicalis)
GRB2:p-4S-SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] (Xenopus tropicalis)
p-Y-IRS:Insulin:p-6Y-Insulin receptor [plasma membrane] (Xenopus tropicalis)
GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] (Xenopus tropicalis)
Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] (Xenopus tropicalis)
as an output of
Dissociation of IRS-P from insulin receptor (Xenopus tropicalis)
GRB2:p-4S-SOS1:p-Y-IRS1,p-Y-IRS2 dissociates (Xenopus tropicalis)
Inferred From
p-Y-IRS1,p-Y-IRS2 [cytosol]
(Homo sapiens)
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