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Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane]
Stable Identifier
R-XTR-198299
Type
Complex
Species
Xenopus tropicalis
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Xenopus tropicalis)
Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by NTRKs (Xenopus tropicalis)
Signaling by NTRK1 (TRKA) (Xenopus tropicalis)
PI3K/AKT activation (Xenopus tropicalis)
Active IRS recruits PI3K to the plasma membrane and activates it (Xenopus tropicalis)
Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] (Xenopus tropicalis)
Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Xenopus tropicalis)
Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] (Xenopus tropicalis)
PI3K produces PIP3 and other phosphatidyl inositides (Xenopus tropicalis)
Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Xenopus tropicalis)
Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] (Xenopus tropicalis)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
mature beta-NGF homodimer [extracellular region]
(Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2 [cytosol]
(Xenopus tropicalis)
x 2
phospho-p-5Y-NTRK1 [plasma membrane]
(Xenopus tropicalis)
Participates
as an input of
Active IRS recruits PI3K to the plasma membrane and activates it (Xenopus tropicalis)
as a component of
Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Xenopus tropicalis)
Inferred From
Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane]
(Homo sapiens)
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