Reactome | phospho-p-3S-POLR2A [nucleoplasm]

phospho-p-3S-POLR2A [nucleoplasm]

Stable Identifier

R-SSC-6797701

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

I3LJR4

Locations in the PathwayBrowser

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Gene expression (Transcription) (Sus scrofa)

- RNA Polymerase II Transcription (Sus scrofa)
  - Generic Transcription Pathway (Sus scrofa)
    - Transcriptional Regulation by TP53 (Sus scrofa)
      - TP53 Regulates Transcription of DNA Repair Genes (Sus scrofa)
        
        CDK12 phosphorylates RNA Pol II CTD at DNA repair genes (Sus scrofa)
        
        CCNK:CDK12:CDK12-Phosphorylated Elongation Complex at DNA repair genes [nucleoplasm] (Sus scrofa)
        
        CDK12-Phosphorylated Elongation Complex [nucleoplasm] (Sus scrofa)
        
        CDK12-phosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Sus scrofa)
        
        p-3S-RNA Pol II:TFIIF [nucleoplasm] (Sus scrofa)
        
        RNA Polymerase II holoenzyme complex phosphorylated by CDK12 [nucleoplasm] (Sus scrofa)
        
        phospho-p-3S-POLR2A [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:I3LJR4

Reference Genes

ENSEMBL:ENSSSCG00000028278.4

UCSC:I3LJR4

Other Identifiers

100737040

GO:0000428

GO:0000791

GO:0001046

GO:0003676

GO:0003677

GO:0003824

GO:0003899

GO:0005634

GO:0005654

GO:0005665

GO:0005694

GO:0005737

GO:0006351

GO:0006366

GO:0016071

GO:0016740

GO:0016779

GO:0016787

GO:0031981

GO:0034062

GO:0042789

GO:0046872

GO:0140098

Participates

as a component of

RNA Polymerase II holoenzyme complex phosphorylated by CDK12 [nucleoplasm] (Sus scrofa)

Other forms of this molecule

POLR2A [nucleoplasm]

phospho-p-S5(CTD)-POLR2A [nucleoplasm]

phospho-p-S2,S5(CTD)-POLR2A [nucleoplasm]

phospho-Ub,p-S2,S5(CTD)-POLR2A [nucleoplasm]

phospho-p-S5,S7(CTD)-POLR2A [nucleoplasm]

phospho-p-S2,S7(CTD)-POLR2A [nucleoplasm]

phospho-p-S2(CTD)-POLR2A [nucleoplasm]

Inferred From

p-3S-POLR2A [nucleoplasm] (Homo sapiens)

Modified Residues

Name

O-phospho-L-serine at unknown position

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

O-phospho-L-serine at unknown position

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

O-phospho-L-serine at unknown position

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Cross References

ENSEMBL

ENSSSCP00000024326, ENSSSCT00000029425, ENSSSCG00000028278

VGNC

91646

PDB

9G0A, 7PKS, 9FYX, 8RBZ, 6GML, 7B7U, 6EXV, 6GMH

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