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VCP [cytosol]
Stable Identifier
R-SCE-1181251
Type
Protein [EntityWithAccessionedSequence]
Species
Saccharomyces cerevisiae
Compartment
cytosol
Synonyms
P25694
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Saccharomyces cerevisiae)
Cellular responses to stress (Saccharomyces cerevisiae)
Cellular response to chemical stress (Saccharomyces cerevisiae)
KEAP1-NFE2L2 pathway (Saccharomyces cerevisiae)
UBXN7 binds VCP hexamer:UBF1:NPLOC4 (Saccharomyces cerevisiae)
NPLOC4:UBF1:VCP hexamer [cytosol] (Saccharomyces cerevisiae)
VCP hexamer [cytosol] (Saccharomyces cerevisiae)
VCP [cytosol] (Saccharomyces cerevisiae)
UBXN7:NPLOC4:UBF1:VCP hexamer [cytosol] (Saccharomyces cerevisiae)
VCP hexamer [cytosol] (Saccharomyces cerevisiae)
VCP [cytosol] (Saccharomyces cerevisiae)
Cellular response to heat stress (Saccharomyces cerevisiae)
HSF1 activation (Saccharomyces cerevisiae)
Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates (Saccharomyces cerevisiae)
HDAC6:VCP:protein aggregates [cytosol] (Saccharomyces cerevisiae)
VCP [cytosol] (Saccharomyces cerevisiae)
HSF1:HSP90:HDAC6:VCP:PTGES3 [cytosol] (Saccharomyces cerevisiae)
VCP [cytosol] (Saccharomyces cerevisiae)
Metabolism of proteins (Saccharomyces cerevisiae)
Post-translational protein modification (Saccharomyces cerevisiae)
Deubiquitination (Saccharomyces cerevisiae)
Ovarian tumor domain proteases (Saccharomyces cerevisiae)
YOD1 binds VCP (Saccharomyces cerevisiae)
VCP [cytosol] (Saccharomyces cerevisiae)
YOD1:VCP [cytosol] (Saccharomyces cerevisiae)
VCP [cytosol] (Saccharomyces cerevisiae)
Neddylation (Saccharomyces cerevisiae)
UBXN7 binds VCP hexamer:UBF1:NPLOC4 (Saccharomyces cerevisiae)
NPLOC4:UBF1:VCP hexamer [cytosol] (Saccharomyces cerevisiae)
VCP hexamer [cytosol] (Saccharomyces cerevisiae)
VCP [cytosol] (Saccharomyces cerevisiae)
UBXN7:NPLOC4:UBF1:VCP hexamer [cytosol] (Saccharomyces cerevisiae)
VCP hexamer [cytosol] (Saccharomyces cerevisiae)
VCP [cytosol] (Saccharomyces cerevisiae)
Protein methylation (Saccharomyces cerevisiae)
VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP (Saccharomyces cerevisiae)
VCP [cytosol] (Saccharomyces cerevisiae)
External Reference Information
External Reference
UniProt:P25694
Reference Genes
BioGPS Gene:851431
ENSEMBL:YDL126C
KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YDL126C
Monarch:851431
NCBI Gene:851431
SGD:YDL126C
Reference Transcript
RefSeq:NM_001180185.1
Other Identifiers
1777140_at
6604_at
851431
GO:0000166
GO:0000278
GO:0000837
GO:0000839
GO:0003674
GO:0005515
GO:0005524
GO:0005575
GO:0005634
GO:0005694
GO:0005737
GO:0005739
GO:0005740
GO:0005783
GO:0005789
GO:0005829
GO:0006260
GO:0006274
GO:0006401
GO:0006414
GO:0006515
GO:0006807
GO:0007005
GO:0007010
GO:0007049
GO:0007059
GO:0008150
GO:0010636
GO:0012505
GO:0015031
GO:0016020
GO:0016197
GO:0016236
GO:0016320
GO:0016570
GO:0016787
GO:0016887
GO:0019888
GO:0030234
GO:0030427
GO:0030433
GO:0030894
GO:0030970
GO:0031134
GO:0031399
GO:0031593
GO:0032182
GO:0032984
GO:0033043
GO:0034098
GO:0034517
GO:0034727
GO:0036266
GO:0042221
GO:0042802
GO:0043130
GO:0043161
GO:0043167
GO:0043170
GO:0043231
GO:0043328
GO:0043332
GO:0043624
GO:0044238
GO:0046034
GO:0048284
GO:0050896
GO:0051052
GO:0051228
GO:0051603
GO:0051974
GO:0055086
GO:0061025
GO:0070647
GO:0070651
GO:0071629
GO:0071630
GO:0071712
GO:0072344
GO:0072671
GO:0097352
GO:0120174
GO:0140657
GO:1900182
GO:1990112
GO:1990116
GO:1990171
GO:2001168
Participates
as an input of
YOD1 binds VCP (Saccharomyces cerevisiae)
VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP (Saccharomyces cerevisiae)
as a component of
YOD1:VCP [cytosol] (Saccharomyces cerevisiae)
HDAC6:VCP:protein aggregates [cytosol] (Saccharomyces cerevisiae)
HSF1:HSP90:HDAC6:VCP:PTGES3 [cytosol] (Saccharomyces cerevisiae)
VCP hexamer [cytosol] (Saccharomyces cerevisiae)
Other forms of this molecule
VCP [ficolin-1-rich granule lumen]
VCP [extracellular region]
VCP [secretory granule lumen]
VCP [azurophil granule lumen]
VCP [nucleoplasm]
Me3K315-VCP [cytosol]
Inferred From
VCP [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_010157.1
PRO
P25694
PDB
8DAS
,
6OAA
,
6OAB
,
6OMB
,
6OA9
,
8DAT
,
8DAV
,
8DAU
,
8DAR
,
6OPC
,
8DAW
Interactors (39)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q04228
3
UBX2 [cytosol]
(R-SCE-6781921)
UBX2 [extracellular region]
(R-SCE-6806183)
UBX2 [azurophil granule lumen]
(R-SCE-6799138)
0.949
16
UniProt:P34223 UBX1
0.933
46
UniProt:P53044
2
UFD1 [nucleoplasm]
(R-SCE-5654993)
UFD1 [cytosol]
(R-SCE-9668519)
0.929
20
UniProt:Q08109 HRD1
0.926
10
UniProt:P33755
2
NPL4 [nucleoplasm]
(R-SCE-5654987)
NPL4 [cytosol]
(R-SCE-9755492)
0.918
15
UniProt:P36037 DOA1
0.84
26
UniProt:Q04311 VMS1
0.839
9
UniProt:P54860
1
UFD2 [cytosol]
(R-SCE-976022)
0.832
13
UniProt:Q06682
2
UBX5 [cytosol]
(R-SCE-9755305)
UBX5 [cytosol]
(R-SCE-8956071)
0.818
7
UniProt:P54730 UBX4
0.814
9
UniProt:Q05787 HRD3
0.784
7
UniProt:P38307 DER1
0.784
5
UniProt:P40318 DOA10
0.773
5
UniProt:P38349 UBX7
0.76
7
UniProt:P43558
1
YOD1 [cytosol]
(R-SCE-6781909)
0.752
6
UniProt:Q99220 OS9
0.708
5
UniProt:Q12229 UBX3
0.632
4
UniProt:Q01477
2
UBP3 [nucleoplasm]
(R-SCE-3222218)
UBP3 [cytosol]
(R-SCE-6782974)
0.632
4
UniProt:Q03714 USA1
0.623
4
UniProt:P06778
3
RAD52 [nucleoplasm]
(R-SCE-4568909)
RAD52 [nucleoplasm]
(R-SCE-62639)
phospho-RAD52 [nucleoplasm]
(R-SCE-5686588)
0.612
4
UniProt:P41832 BNI1
0.592
3
UniProt:P53741 BRE5
0.591
4
UniProt:P25694
7
VCP [cytosol]
(R-SCE-1181251)
VCP [ficolin-1-rich granule lumen]
(R-SCE-6800425)
VCP [extracellular region]
(R-SCE-6806191)
VCP [secretory granule lumen]
(R-SCE-6801039)
VCP [azurophil granule lumen]
(R-SCE-6800438)
VCP [nucleoplasm]
(R-SCE-5643745)
Me3K315-VCP [cytosol]
(R-SCE-8932209)
0.59
3
UniProt:P53139 YGK8
0.573
3
UniProt:P53899 CUZ1
0.573
2
UniProt:P04838 UBIQ
0.571
3
UniProt:Q12306
5
SMT3 [cytosol]
(R-SCE-4656941)
SMT3 [nucleoplasm]
(R-SCE-3730622)
SMT3 [nucleoplasm]
(R-SCE-3730616)
SMT3 [nucleoplasm]
(R-SCE-877304)
SMT3 [nucleoplasm]
(R-SCE-2990831)
0.567
3
UniProt:P38987 TEM1
0.564
4
UniProt:P02994
6
Me3K79-EEF1A1 [cytosol]
(R-SCE-8932212)
Me3K318-EEF1A1 [cytosol]
(R-SCE-8932419)
EEF1A1 [secretory granule lumen]
(R-SCE-6801479)
EEF1A1 [extracellular region]
(R-SCE-6806456)
EEF1A1 [ficolin-1-rich granule lumen]
(R-SCE-6801528)
EEF1A1 [cytosol]
(R-SCE-156905)
0.527
2
UniProt:P21771 RT28
0.527
2
UniProt:P53063 DXO
0.527
2
UniProt:Q12743 DFM1
0.527
2
UniProt:Q00816 REG1
0.527
2
UniProt:P10591
17
SSA1 [ficolin-1-rich granule lumen]
(R-SCE-6801512-2)
SSA1 [ficolin-1-rich granule lumen]
(R-SCE-6801496-2)
SSA1 [extracellular region]
(R-SCE-6805872-2)
SSA1 [extracellular region]
(R-SCE-6806500-2)
SSA1 [secretory granule lumen]
(R-SCE-6801472-2)
SSA1 [cytosol]
(R-SCE-3371410-2)
SSA1 [cytosol]
(R-SCE-3371408-2)
SSA1 [cytosol]
(R-SCE-6792602-2)
SSA1 [nucleoplasm]
(R-SCE-6792605-2)
SSA1 [nucleoplasm]
(R-SCE-912480-2)
SSA1 [nucleoplasm]
(R-SCE-5082367-2)
SSA1 [nucleoplasm]
(R-SCE-5252082-2)
SSA1 [nucleoplasm]
(R-SCE-5252088-2)
SSA1 [nucleoplasm]
(R-SCE-5252009-2)
SSA1 [cytosol]
(R-SCE-5251948-2)
SSA1 [cytosol]
(R-SCE-5251981-2)
SSA1 [cytosol]
(R-SCE-3371521-2)
0.527
2
UniProt:P10592
20
SSA2 [cytosol]
(R-SCE-264476)
SSA2 [nucleoplasm]
(R-SCE-5082380)
SSA2 [ficolin-1-rich granule lumen]
(R-SCE-6801512-3)
SSA2 [ficolin-1-rich granule lumen]
(R-SCE-6801496-3)
SSA2 [ficolin-1-rich granule lumen]
(R-SCE-6801494)
SSA2 [extracellular region]
(R-SCE-6805872-3)
SSA2 [extracellular region]
(R-SCE-6806500-3)
SSA2 [extracellular region]
(R-SCE-6805936)
SSA2 [secretory granule lumen]
(R-SCE-6801530)
SSA2 [secretory granule lumen]
(R-SCE-6801472-3)
SSA2 [cytosol]
(R-SCE-3371410-3)
SSA2 [cytosol]
(R-SCE-3371408-3)
SSA2 [cytosol]
(R-SCE-6792602-3)
SSA2 [nucleoplasm]
(R-SCE-6792605-3)
SSA2 [nucleoplasm]
(R-SCE-912480-3)
SSA2 [nucleoplasm]
(R-SCE-5082367-3)
SSA2 [nucleoplasm]
(R-SCE-5252082-3)
SSA2 [nucleoplasm]
(R-SCE-5252088-3)
SSA2 [nucleoplasm]
(R-SCE-5252009-3)
SSA2 [cytosol]
(R-SCE-5251948-3)
0.527
2
UniProt:P00729 CBPY
0.527
2
UniProt:P24814 GRR1
0.527
2
UniProt:P47049 UBX6
0.508
3
UniProt:P32628
2
RAD23 [nucleoplasm]
(R-SCE-62590)
RAD23 [nucleoplasm]
(R-SCE-5688076)
0.499
2
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