Reactome | RAD52 [nucleoplasm]

RAD52 [nucleoplasm]

Stable Identifier

R-SCE-4568909

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

monoSUMO1-K411,K412,K414-RAD52, P06778

Locations in the PathwayBrowser

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Metabolism of proteins (Saccharomyces cerevisiae)

- Post-translational protein modification (Saccharomyces cerevisiae)
  - SUMOylation (Saccharomyces cerevisiae)
    - SUMO E3 ligases SUMOylate target proteins (Saccharomyces cerevisiae)
      - SUMOylation of DNA damage response and repair proteins (Saccharomyces cerevisiae)
        
        SUMOylation of RAD52 with SUMO1 (Saccharomyces cerevisiae)
        
        RAD52 [nucleoplasm] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P06778

Gene Names

RAD52

Reference Genes

BioGPS Gene:854976 RAD52

ENSEMBL:YML032C

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YML032C RAD52

Monarch:854976 RAD52

NCBI Gene:854976 RAD52

SGD:YML032C

Reference Transcript

RefSeq:NM_001182390.1 RAD52

Other Identifiers

1771648_at

854976

9677_at

GO:0000150

GO:0000228

GO:0000709

GO:0000722

GO:0000724

GO:0000727

GO:0000730

GO:0000733

GO:0003674

GO:0003677

GO:0005515

GO:0005575

GO:0005634

GO:0005694

GO:0005737

GO:0005739

GO:0006277

GO:0006281

GO:0006301

GO:0006310

GO:0006312

GO:0006974

GO:0007005

GO:0008150

GO:0032200

GO:0043504

GO:0045002

GO:0048285

GO:0051052

GO:0051321

GO:1904877

GO:1990814

Participates

as an output of

SUMOylation of RAD52 with SUMO1 (Saccharomyces cerevisiae)

Other forms of this molecule

RAD52 [nucleoplasm]

phospho-RAD52 [nucleoplasm]

Inferred From

monoSUMO1-K411,K412,K414-RAD52 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

sumoylated lysine (monoSUMO1 [nucleoplasm]) at 411 (in Homo sapiens)

Coordinate

411

Modification

monoSUMO1 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Name

sumoylated lysine (monoSUMO1 [nucleoplasm]) at 412 (in Homo sapiens)

Coordinate

412

Modification

monoSUMO1 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Name

sumoylated lysine (monoSUMO1 [nucleoplasm]) at 414 (in Homo sapiens)

Coordinate

414

Modification

monoSUMO1 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Cross References

RefSeq

NP_013680.2

OpenTargets

ENSG00000002016

PRO

P06778

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P25454	2	RAD51 [nucleoplasm] (R-SCE-62637) phospho-p-T309-RAD51 [nucleoplasm] (R-SCE-5685231)	0.838	17
UniProt:P25694	7	VCP [cytosol] (R-SCE-1181251) VCP [ficolin-1-rich granule lumen] (R-SCE-6800425) VCP [extracellular region] (R-SCE-6806191) VCP [secretory granule lumen] (R-SCE-6801039) VCP [azurophil granule lumen] (R-SCE-6800438) VCP [nucleoplasm] (R-SCE-5643745) Me3K315-VCP [cytosol] (R-SCE-8932209)	0.612	4
UniProt:Q12306	4	SMT3 [nucleoplasm] (R-SCE-2990831) SMT3 [nucleoplasm] (R-SCE-877304) SMT3 [nucleoplasm] (R-SCE-3730616) SMT3 [nucleoplasm] (R-SCE-3730622)	0.589	2
UniProt:P15108	6	HSP90AA1 [plasma membrane] (R-SCE-534996-2) HSP90AA1 [secretory granule lumen] (R-SCE-6801515-2) HSP90AA1 [extracellular region] (R-SCE-3221946-2) HSP90AA1 [ficolin-1-rich granule lumen] (R-SCE-6801470-2) HSP90AA1 [nucleoplasm] (R-SCE-5082401-2) HSP90AA1 [cytosol] (R-SCE-192864-2)	0.564	2
UniProt:P53044	1	UFD1 [cytosol] (R-SCE-9668519)	0.558	4
UniProt:P11484	2	HSPA2 [nucleoplasm] (R-SCE-912480-4) HSPA2 [cytosol] (R-SCE-3371408-4)	0.527	3