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Akr1c1 [cytosol]
Stable Identifier
R-RNO-192142
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
AKR1C4, Q3MHS3
Locations in the PathwayBrowser
Expand all
Drug ADME (Rattus norvegicus)
Prednisone ADME (Rattus norvegicus)
AKR1C1 hydrogenates PREDN,PREDL (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
Akr1c1 [cytosol] (Rattus norvegicus)
Metabolism (Rattus norvegicus)
Metabolism of lipids (Rattus norvegicus)
Fatty acid metabolism (Rattus norvegicus)
Arachidonate metabolism (Rattus norvegicus)
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Rattus norvegicus)
PGD2 is reduced to 11-epi-PGF2a by AKRIC3 (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
Akr1c1 [cytosol] (Rattus norvegicus)
PGH2 is reduced to PGF2a by AKR1C3 (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
Akr1c1 [cytosol] (Rattus norvegicus)
Metabolism of steroids (Rattus norvegicus)
Bile acid and bile salt metabolism (Rattus norvegicus)
Synthesis of bile acids and bile salts (Rattus norvegicus)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Rattus norvegicus)
5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol (Rattus norvegicus)
Aldo-keto reductase family [cytosol] (Rattus norvegicus)
Akr1c1 [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
Akr1c1 [cytosol] (Rattus norvegicus)
5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol (Rattus norvegicus)
Aldo-keto reductase family [cytosol] (Rattus norvegicus)
Akr1c1 [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
Akr1c1 [cytosol] (Rattus norvegicus)
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Rattus norvegicus)
5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol (Rattus norvegicus)
Aldo-keto reductase family [cytosol] (Rattus norvegicus)
Akr1c1 [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
Akr1c1 [cytosol] (Rattus norvegicus)
5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol (Rattus norvegicus)
Aldo-keto reductase family [cytosol] (Rattus norvegicus)
Akr1c1 [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
Akr1c1 [cytosol] (Rattus norvegicus)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Rattus norvegicus)
5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol (Rattus norvegicus)
Aldo-keto reductase family [cytosol] (Rattus norvegicus)
Akr1c1 [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
Akr1c1 [cytosol] (Rattus norvegicus)
5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol (Rattus norvegicus)
Aldo-keto reductase family [cytosol] (Rattus norvegicus)
Akr1c1 [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
Akr1c1 [cytosol] (Rattus norvegicus)
Metabolism of vitamins and cofactors (Rattus norvegicus)
Metabolism of fat-soluble vitamins (Rattus norvegicus)
Retinoid metabolism and transport (Rattus norvegicus)
AKRs reduce RBP2:atRAL to RBP2:atROL (Rattus norvegicus)
AKRs [cytosol] (Rattus norvegicus)
Akr1c1 [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
Akr1c1 [cytosol] (Rattus norvegicus)
Sensory Perception (Rattus norvegicus)
Visual phototransduction (Rattus norvegicus)
Retinoid metabolism and transport (Rattus norvegicus)
AKRs reduce RBP2:atRAL to RBP2:atROL (Rattus norvegicus)
AKRs [cytosol] (Rattus norvegicus)
Akr1c1 [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
Akr1c1 [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Signaling by Nuclear Receptors (Rattus norvegicus)
Signaling by Retinoic Acid (Rattus norvegicus)
RA biosynthesis pathway (Rattus norvegicus)
AKR1C3 reduces atRAL to atROL (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
Akr1c1 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:Q3MHS3
Gene Names
Akr1c1
Reference Genes
BioGPS Gene:307092 Akr1c1
ENSEMBL:ENSRNOG00000038331
KEGG:rno:307092 Akr1c1
Monarch:307092 Akr1c1
NCBI Gene:307092 Akr1c1
UCSC:Q3MHS3 Akr1c1
Reference Transcript
RefSeq:NM_001033697.1 Akr1c1
Other Identifiers
10799328
1393902_at
17720497
307092
5618343
5794011
5859231
5967896
6022865
6196271
6224375
6248436
6278531
6375825
6667572
6708263
GO:0004032
GO:0004303
GO:0005829
GO:0006629
GO:0006694
GO:0007586
GO:0008202
GO:0008206
GO:0009410
GO:0016491
GO:0016655
GO:0030154
GO:0030855
GO:0031406
GO:0032052
GO:0042448
GO:0042574
GO:0043627
GO:0044597
GO:0044598
GO:0047006
GO:0047045
GO:0047086
GO:0047115
GO:0048025
GO:0071395
GO:1901135
GO:2000379
PH_rn_0012653
rc_AI072107_at
Participates
as a member of
AKRs [cytosol] (Rattus norvegicus)
Aldo-keto reductase family [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
Inferred From
AKR1C4 [cytosol]
(Homo sapiens)
AKR1C1 [cytosol]
(Homo sapiens)
AKR1C2 [cytosol]
(Homo sapiens)
AKR1C3 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001028869.1
ENSEMBL
ENSRNOG00000038331
,
ENSRNOT00000058367
,
ENSRNOP00000055169
RGD
1306847
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