Reactome | Tln1(433-2541) [cytosol]

Tln1(433-2541) [cytosol]

Stable Identifier

R-MMU-9855172

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

Talin-1, TLN1_MOUSE

External Reference Information

External Reference

UniProt:P26039 Tln1

Gene Names

Tln1, Tln

Chain

chain:1-2541

Reference Genes

BioGPS Gene:21894 Tln1

KEGG:mmu:21894 Tln1

Monarch:21894 Tln1

NCBI Gene:21894 Tln1

UCSC:P26039 Tln1

Reference Transcript

RefSeq:NM_011602.5 Tln1

Other Identifiers

102732_at

10512514

1436042_at

1448402_at

1457782_at

17424674

21894

4320941

4336123

4338516

4343823

4353403

4388363

4418408

4477793

4500588

4506789

4514405

4521208

4530210

4530481

4531701

4557168

4577708

4615859

4616749

4657040

4659256

4678104

4697670

4707233

4756247

4769975

4780829

4791092

4808395

4810210

4820953

4872546

4898060

4923499

4931982

4955068

4995242

5019625

5042600

5088475

5107709

5109413

5121754

5144398

5195153

5201031

5204336

5248529

5249355

5338916

5373673

5391787

5422092

5435987

5449676

5452989

5454845

5471509

5475913

5492609

5502327

5527696

5530919

5550345

5561056

5602851

99448_at

A_51_P446865

A_52_P15076

A_52_P50376

A_55_P1956973

A_55_P1956978

GE36209

GO:0001726

GO:0001786

GO:0003779

GO:0005178

GO:0005198

GO:0005200

GO:0005515

GO:0005737

GO:0005829

GO:0005856

GO:0005886

GO:0005912

GO:0005925

GO:0007010

GO:0007044

GO:0007155

GO:0007229

GO:0008092

GO:0009986

GO:0016020

GO:0017166

GO:0030036

GO:0030274

GO:0030866

GO:0032587

GO:0033622

GO:0034329

GO:0034330

GO:0035091

GO:0042995

GO:0043622

GO:0051015

GO:0065003

GO:0070161

GO:0098609

ILMN_1251985

ILMN_2605679

Msa.2712.0_f_at

aa009154_s_at

mMC001945

x56123-2_f_at

Participates

as an output of

Calpain2 cleaves Tln1 (Talin-1) (Mus musculus)

Other forms of this molecule

Tln1 [cytosol]

Tln1(1-432) [cytosol]

Tln1 [extracellular region]

Cross References

ENSEMBL

ENSMUSP00000030187, ENSMUSG00000028465, ENSMUST00000030187

PRO

P26039

MGI

1099832

GlyGen

P26039

PDB

6TWN, 2QDQ, 8T0A, 8T0D, 8VDO, 8VDQ, 6BA6, 5IC1, 5IC0, 1T01, 1U89, 3DYJ, 2L10, 2L7A, 7ZW4, 8FTB, 3S90, 2KC2, 9C1T, 2X0C, 2KGX, 1Y19, 6MFS, 8FSO, 2KVP, 2KMA, 3IVF, 8VDR, 5FZT, 8VDP, 5NL1, 2KC1, 9DZ5, 8FSE, 2JSW, 4F7G, 1ZW3, 1SJ7, 4W8P, 2G35, 2B0H, 7V1A, 8IVZ, 1SJ8, 8AS9, 2LQG, 2KBB, 6VGU, 2L7N, 9AZ6

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P05106 ITGB3	3	ITGB3 [plasma membrane] (R-HSA-57600) ITGB3(27-?) [platelet alpha granule membrane] (R-HSA-114512) p-T779-ITGB3 [plasma membrane] (R-HSA-432107)	0.842	8
UniProt:P12003	6	VCL [cytosol] (R-GGA-9861471) VCL [secretory granule lumen] (R-GGA-6801010) VCL [specific granule lumen] (R-GGA-6799711) VCL [extracellular region] (R-GGA-350736) VCL [ficolin-1-rich granule lumen] (R-GGA-6800985) VCL [cytosol] (R-GGA-350753)	0.766	5
UniProt:Q8R5A3	1	Apbb1ip [cytosol] (R-MMU-354081)	0.737	8
UniProt:P05556 ITGB1	2	ITGB1 [plasma membrane] (R-HSA-57596) ITGB1 [endosome membrane] (R-HSA-9611157)	0.571	2
IntAct:EBI-1185723 ITGB3			0.558	4
UniProt:Q64727	6	Vcl [cytosol] (R-MMU-9861471) Vcl [secretory granule lumen] (R-MMU-6801010) Vcl [specific granule lumen] (R-MMU-6799711) Vcl [extracellular region] (R-MMU-350736) Vcl [ficolin-1-rich granule lumen] (R-MMU-6800985) Vcl [cytosol] (R-MMU-350753)	0.499	2

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