Reactome | FZD8 [plasma membrane]

FZD8 [plasma membrane]

Stable Identifier

R-MMU-443947

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

Q61091

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q61091 Fzd8

Gene Names

Fzd8

Chain

signal peptide:1-27, chain:28-685

Reference Genes

BioGPS Gene:14370 Fzd8

KEGG:mmu:14370 Fzd8

Monarch:14370 Fzd8

NCBI Gene:14370 Fzd8

UCSC:Q61091 Fzd8

Reference Transcript

RefSeq:NM_008058.2 Fzd8

Other Identifiers

10453738

110015_at

1423348_at

14370

1445815_at

166437_f_at

17348276

4418857

4439496

4534995

4595142

4724423

4963064

5202021

5349189

5351727

5356916

5397527

5400270

5528333

5539143

5541997

5565322

99415_at

A_51_P312517

A_52_P676589

A_55_P2035804

GE34436

GO:0001525

GO:0001934

GO:0002376

GO:0004888

GO:0004930

GO:0005102

GO:0005515

GO:0005576

GO:0005794

GO:0005886

GO:0007166

GO:0007186

GO:0016020

GO:0016055

GO:0017147

GO:0030154

GO:0030165

GO:0031410

GO:0031625

GO:0033077

GO:0035567

GO:0042813

GO:0043226

GO:0060070

GO:0060089

GO:0098992

GO:1990851

ILMN_2597578

Msa.1894.0_at

Msa.1894.0_g_at

mMC019983

Participates

as a candidate of

Other forms of this molecule

ub-FZD8 [plasma membrane]

mFz8CRD [extracellular region]

Fzd8 [plasma membrane]

Inferred From

FZD8 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_032084.2

ENSEMBL

ENSMUSP00000039660, ENSMUST00000041080

PRO

Q61091

GlyGen

Q61091

MGI

108460

PDB

6AHY, 6TFB, 6TFM, 8CTG, 4F0A, 1IJY

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P27467 Wnt3a	12	N4GlycoAsn-PalmS Wnt3a [extracellular region] (R-MMU-3769340) Wnt3a [extracellular region] (R-MMU-3772390) Wnt3a [extracellular exosome] (R-MMU-3781968) Wnt3a [endocytic vesicle membrane] (R-MMU-3781944) Wnt3a [early endosome membrane] (R-MMU-5368483) N4GlycoAsn-PalmS Wnt3a [endoplasmic reticulum lumen] (R-MMU-3238346) N-glycosyl Wnt3a [endoplasmic reticulum lumen] (R-MMU-3238233) Wnt3a [endoplasmic reticulum lumen] (R-MMU-3238294) Wnt3a [endoplasmic reticulum lumen] (R-MMU-3238344) Wnt3a [Golgi lumen] (R-MMU-3247832) Wnt3a [extracellular region] (R-MMU-3247784) Wnt3a [plasma membrane] (R-MMU-3247807)	0.825	7
UniProt:O75581 LRP6	8	LRP6 [plasma membrane] (R-HSA-206252) p-4S,3T,T1479,S1490,T1493-LRP6 [plasma membrane] (R-HSA-1458895) p-2S,S1490,2T-LRP6 [plasma membrane] (R-HSA-1458894) LRP6N [extracellular region] (R-HSA-5334021) p-LRP6 [early endosome membrane] (R-HSA-5368496) LRP6 [early endosome membrane] (R-HSA-5368481) p-S1490-LRP6 [plasma membrane] (R-HSA-206156) p-T1479,S1490,T1493-LRP6 [plasma membrane] (R-HSA-205884)	0.702	4
UniProt:P28026 wnt8	1	Wnt-8 [extracellular region] (R-XLA-517412)	0.618	3
UniProt:Q8BH60	3	Gopc [lysosomal membrane] (R-MMU-5627281) Gopc [plasma membrane] (R-MMU-5626572) Gopc [Golgi-associated vesicle membrane] (R-MMU-5627067)	0.581	3
UniProt:P56703 WNT3	9	WNT3 [extracellular region] (R-HSA-201676) N4GlycoAsn-PalmS WNT3 [extracellular exosome] (R-HSA-3781966) N4GlycoAsn-PalmS WNT3 [endocytic vesicle membrane] (R-HSA-3781967) WNT3 [endoplasmic reticulum lumen] (R-HSA-3238288) N4GlycoAsn-WNT3 [endoplasmic reticulum lumen] (R-HSA-3238227) N4GlycoAsn-PalmS WNT3 [endoplasmic reticulum lumen] (R-HSA-3238342) N4GlycoAsn-PalmS WNT3 [Golgi lumen] (R-HSA-3247818) N4GlycoAsn-PalmS WNT3 [extracellular region] (R-HSA-3247786) N4GlycoAsn-PalmS WNT3 [plasma membrane] (R-HSA-3247830)	0.558	2

© 2025 Reactome

Cite Us!