Reactome | WNT3 [extracellular region]

WNT3 [extracellular region]

Stable Identifier

R-HSA-201676

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P56703 WNT3

Gene Names

WNT3, INT4

Chain

signal peptide:1-21, chain:22-355

Reference Genes

BioGPS Gene:7473 WNT3

COSMIC (genes):WNT3 WNT3

CTD Gene:7473 WNT3

dbSNP Gene:7473 WNT3

ENSEMBL:ENSG00000108379 WNT3

HGNC:12782 WNT3

KEGG:hsa:7473 WNT3

Monarch:7473 WNT3

NCBI Gene:7473 WNT3

OMIM:165330 WNT3

UCSC:P56703 WNT3

Reference Transcript

RefSeq:NM_030753.4 WNT3

Other Identifiers

101929777

11736767_at

11759217_at

16846022

16846029

16850379

221455_PM_s_at

221455_s_at

229103_PM_at

229103_at

231743_PM_at

231743_at

3760494

3760495

3760496

3760497

3760498

3760499

3760500

3760501

3760502

3760503

3760507

3760508

3760510

3760511

3760512

3760514

56093_at

73055_at

7473

8016311

ADDON001990.hg

A_23_P130158

A_33_P3383174

GE86328

GE885223

GO:0000902

GO:0001707

GO:0005102

GO:0005109

GO:0005125

GO:0005515

GO:0005576

GO:0005615

GO:0005788

GO:0005796

GO:0005886

GO:0007275

GO:0007276

GO:0007411

GO:0009948

GO:0009950

GO:0009952

GO:0010467

GO:0010468

GO:0010628

GO:0016055

GO:0019904

GO:0022414

GO:0030154

GO:0030177

GO:0030182

GO:0030312

GO:0030666

GO:0031012

GO:0035115

GO:0035116

GO:0043226

GO:0044338

GO:0045165

GO:0045669

GO:0048018

GO:0048646

GO:0048697

GO:0048843

GO:0048856

GO:0050767

GO:0060064

GO:0060070

GO:0060173

GO:0060174

GO:0060323

GO:0061180

GO:0070062

GO:0071300

GO:0072089

GO:0098772

GO:1904948

GO:1990909

GO:2000739

HMNXSV003020676

HMNXSV003043859

HMNXSV003045199

Hs.224667.0.S1_3p_at

Hs.99597.0.A1_3p_at

ILMN_1652466

ILMN_1803593

PH_hs_0012570

TC17001615.hg

TC17002678.hg

g13540476_3p_s_at

p20175

Participates

as a member of

WNTs [extracellular region] (Homo sapiens)

Other forms of this molecule

N4GlycoAsn-PalmS WNT3 [extracellular exosome]

N4GlycoAsn-PalmS WNT3 [endocytic vesicle membrane]

WNT3 [endoplasmic reticulum lumen]

N4GlycoAsn-WNT3 [endoplasmic reticulum lumen]

N4GlycoAsn-PalmS WNT3 [endoplasmic reticulum lumen]

N4GlycoAsn-PalmS WNT3 [Golgi lumen]

N4GlycoAsn-PalmS WNT3 [extracellular region]

N4GlycoAsn-PalmS WNT3 [plasma membrane]

Cross References

RefSeq

NP_110380.1

ENSEMBL

ENST00000616347, ENSP00000225512, ENST00000611547, ENSP00000480990, ENST00000225512, ENSP00000478327

OpenTargets

ENSG00000108379

HPA

ENSG00000108379-WNT3

ZINC - Substances

WNT3_HUMAN

ZINC target

P56703

PRO

P56703

Pharos - Targets

P56703

GlyGen

P56703

Orphanet

WNT3

ZINC - Predictions - Purchasable

WNT3_HUMAN

PDB

6AHY

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75084 FZD7	1	FZD7 [plasma membrane] (R-HSA-517394)	0.589	3
UniProt:Q61091 Fzd8	4	ub-FZD8 [plasma membrane] (R-MMU-4641183) FZD8 [plasma membrane] (R-MMU-443947) mFz8CRD [extracellular region] (R-MMU-1458870) Fzd8 [plasma membrane] (R-MMU-517517)	0.558	2
UniProt:P56704 WNT3A	10	N4GlycoAsn-PalmS WNT3A [plasma membrane] (R-HSA-3247807) N4GlycoAsn-PalmS WNT3A [extracellular region] (R-HSA-3247784) N4GlycoAsn-PalmS WNT3A [Golgi lumen] (R-HSA-3247832) N4GlycoAsn-PalmS WNT3A [endoplasmic reticulum lumen] (R-HSA-3238344) N4GlycoAsn-WNT3A [endoplasmic reticulum lumen] (R-HSA-3238231) WNT3A [endoplasmic reticulum lumen] (R-HSA-3238292) N4GlycoAsn-PalmS WNT3A [early endosome membrane] (R-HSA-5368483) N4GlycoAsn-PalmS WNT3A [endocytic vesicle membrane] (R-HSA-3781944) N4GlycoAsn-PalmS WNT3A [extracellular exosome] (R-HSA-3781968) WNT3A [extracellular region] (R-HSA-201710)	0.527	2