Reactome | PTPRA [plasma membrane]

PTPRA [plasma membrane]

Stable Identifier

R-MMU-388755

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

P18052

Locations in the PathwayBrowser

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Signal Transduction (Mus musculus)

- MAPK family signaling cascades (Mus musculus)
  - MAPK1/MAPK3 signaling (Mus musculus)
    - RAF/MAP kinase cascade (Mus musculus)
      - RAS GEFs promote RAS nucleotide exchange (Mus musculus)
        
        RAS GEFs [plasma membrane] (Mus musculus)
        
        Grb2:Sos:pFAK bound to NCAM1:pFyn [plasma membrane] (Mus musculus)
        
        NCAM1 complexed with pFyn-Y420 [plasma membrane] (Mus musculus)
        
        PTPRA [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:P18052

Reference Genes

BioGPS Gene:19262

ENSEMBL:ENSMUSG00000027303

KEGG:mmu:19262

Monarch:19262

NCBI Gene:19262

UCSC:P18052

Reference Transcript

RefSeq:NM_008980.2

Other Identifiers

100908_at

10476163

138497_at

1425340_a_at

1447467_at

17376341

19262

4371089

4386989

4395640

4449989

4450124

4492374

4515682

4613252

4637657

4651481

4653435

4684033

4708491

4728358

4736811

4774932

4787898

4821064

4876970

4885838

4888529

4966800

4986304

4990897

5022290

5034807

5038781

5041437

5046592

5052422

5132550

5265012

5306519

5306701

5333407

5341131

5365991

5408597

5574348

5578720

A_51_P382194

A_55_P1992074

GE110834

GE34299

GO:0003824

GO:0004721

GO:0004725

GO:0005515

GO:0005886

GO:0005925

GO:0006470

GO:0007165

GO:0007229

GO:0008286

GO:0016020

GO:0016311

GO:0016787

GO:0043235

GO:0050804

GO:0051893

GO:0070161

GO:0097060

GO:0098685

GO:0140096

ILMN_1238137

ILMN_2607022

M36033_s_at

mMC009541

Participates

as a component of

NCAM1 complexed with pFyn-Y420 [plasma membrane] (Mus musculus)

Inferred From

PTPRA [plasma membrane] (Homo sapiens)

Cross References

ENSEMBL

ENSMUSG00000027303, ENSMUST00000077303, ENSMUSP00000076533

PRO

P18052

GlyGen

P18052

MGI

97808

PDB

1YFO, 1P15

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q60631 Grb2	3	Grb2 [cytosol] (R-MMU-74686) Grb2 [plasma membrane] (R-MMU-202993) Grb2 [cytosol] (R-MMU-443287)	0.656	4
UniProt:P39688 Fyn	6	Fyn [cytosol] (R-MMU-420333) phospho-MyrG-p-Y420-FYN-1 [plasma membrane] (R-MMU-9032530) pFyn (420) [cytosol] (R-MMU-420335) pFyn(Y531) [cytosol] (R-MMU-420350) phospho-p-S21,Y420-FYN [cytosol] (R-MMU-5218745) MyrG,p-Y420-Fyn [plasma membrane] (R-MMU-9037733)	0.564	2
UniProt:P70232 Chl1	1	CHL1_MOUSE [plasma membrane] (R-MMU-443584)	0.556	4
UniProt:P00523 SRC	2	Src [cytosol] (R-GGA-3928468) MyrG-p-Y416-SRC [plasma membrane] (R-GGA-9968036)	0.525	2