Dephosphorylation of JAK1 by SHP1

Stable Identifier
R-HSA-997314
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
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SHP1 directly associates with and dephosphorylates JAK1/2.
Literature References
PubMed ID Title Journal Year
18508557 Protein tyrosine phosphatases in the JAK/STAT pathway

Xu, D, Qu, CK

Front Biosci 2008
8943354 Direct association with and dephosphorylation of Jak2 kinase by the SH2-domain-containing protein tyrosine phosphatase SHP-1

Jiao, H, Platanias, LC, Yi, T, Yang, W, Tabrizi, M, Berrada, K

Mol Cell Biol 1996
Participants
Participates
Catalyst Activity

protein tyrosine phosphatase activity of PTPN6 [cytosol]

Orthologous Events
Authored
Reviewed
Created
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