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Expression of DLL1 during nephron development
Stable Identifier
R-HSA-9832209
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
,
plasma membrane
ReviewStatus
3/5
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Developmental Biology (Homo sapiens)
Kidney development (Homo sapiens)
Nephron development (Homo sapiens)
Expression of DLL1 during nephron development (Homo sapiens)
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DLL1 is expressed in the distal regions of renal vesicles and comma-shaped bodies and in proximal regions of S-shaped bodies (inferred from mouse embryos). LHX1 activates DLL1 expression in renal vesicles (inferred from mouse homologs) then HNF1B enhances DLL1 expression in comma-shaped bodies and S-shaped bodies (inferred from mouse homologs).
Participants
Input
DLL1 gene [nucleoplasm]
(Homo sapiens)
Output
DLL1 [plasma membrane]
(Homo sapiens)
Participates
as an event of
Nephron development (Homo sapiens)
This event is regulated
Positively by
Regulator
LHX1 [nucleoplasm]
(Homo sapiens)
Regulator
HNF1B:DLL1 gene [nucleoplasm]
(Homo sapiens)
Active Unit
HNF1B [nucleoplasm]
Inferred From
Expression of Dll1 during nephron development (Mus musculus)
Authored
May, B (2023-03-28)
Created
May, B (2023-03-29)
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