Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
LHX1 [nucleoplasm]
Stable Identifier
R-HSA-9761188
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
LIM/homeobox protein Lhx1, LHX1_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Gastrulation (Homo sapiens)
Formation of intermediate mesoderm (Homo sapiens)
Expression of LHX1 in intermediate mesoderm (Homo sapiens)
LHX1 [nucleoplasm] (Homo sapiens)
Expression of PAX2 in intermediate mesoderm (Homo sapiens)
LHX1 [nucleoplasm] (Homo sapiens)
Kidney development (Homo sapiens)
Formation of the nephric duct (Homo sapiens)
Expression of EMX2 in the nephric duct (Homo sapiens)
LHX1 [nucleoplasm] (Homo sapiens)
Expression of GATA3 in the nephric duct (Homo sapiens)
LHX1 [nucleoplasm] (Homo sapiens)
Expression of LHX1 (LIM1) in the nephric duct (Homo sapiens)
LHX1 [nucleoplasm] (Homo sapiens)
Expression of MECOM (EVI1) in the nephric duct (Homo sapiens)
LHX1 [nucleoplasm] (Homo sapiens)
Expression of NPNT in the nephric duct (Homo sapiens)
LHX1 [nucleoplasm] (Homo sapiens)
LHX1:NPNT gene [nucleoplasm] (Homo sapiens)
LHX1 [nucleoplasm] (Homo sapiens)
Expression of PAX2 in intermediate mesoderm (Homo sapiens)
LHX1 [nucleoplasm] (Homo sapiens)
Expression of PCDH19 in the nephric duct (Homo sapiens)
LHX1 [nucleoplasm] (Homo sapiens)
LHX1 binds the NPNT gene (Homo sapiens)
LHX1 [nucleoplasm] (Homo sapiens)
LHX1:NPNT gene [nucleoplasm] (Homo sapiens)
LHX1 [nucleoplasm] (Homo sapiens)
Nephron development (Homo sapiens)
Expression of DLL1 during nephron development (Homo sapiens)
LHX1 [nucleoplasm] (Homo sapiens)
Expression of LHX1 during nephron development (Homo sapiens)
LHX1 [nucleoplasm] (Homo sapiens)
Expression of POU3F3 during nephron development (Homo sapiens)
LHX1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P48742 LHX1
Gene Names
LHX1, LIM-1, LIM1
Chain
chain:1-406
Reference Genes
BioGPS Gene:3975 LHX1
CTD Gene:3975 LHX1
dbSNP Gene:3975 LHX1
ENSEMBL:ENSG00000273706 LHX1
ENSEMBL_homo_sapiens_GENE:ENSG00000273706.5 LHX1
ENSEMBL_homo_sapiens_GENE:ENSG00000274577.2 LHX1
HGNC:6593 LHX1
KEGG Gene (Homo sapiens):3975 LHX1
Monarch:3975 LHX1
NCBI Gene:3975 LHX1
OMIM:601999 LHX1
UCSC:P48742 LHX1
Reference Transcript
RefSeq:NM_005568.4 LHX1
Other Identifiers
11736682_at
11759211_at
16833502
206230_PM_at
206230_at
295_s_at
35388_at
3719345
3719346
3719347
3719348
3719349
3719351
3719352
3719353
3719356
3719357
3719358
3719359
3719361
3975
8006681
91336_at
A_14_P102912
A_23_P78061
A_33_P3409854
GE80232
GE834241
GE856761
GO:0000785
GO:0000977
GO:0000981
GO:0000987
GO:0001655
GO:0001656
GO:0001657
GO:0001658
GO:0001702
GO:0001705
GO:0001706
GO:0001822
GO:0001823
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0005667
GO:0005694
GO:0006351
GO:0006355
GO:0006357
GO:0006366
GO:0007267
GO:0007389
GO:0007399
GO:0007492
GO:0008045
GO:0008270
GO:0009653
GO:0009791
GO:0009880
GO:0009887
GO:0009948
GO:0009952
GO:0009953
GO:0010468
GO:0010842
GO:0021510
GO:0021517
GO:0021527
GO:0021537
GO:0021549
GO:0021702
GO:0021871
GO:0021937
GO:0022414
GO:0023052
GO:0030154
GO:0030182
GO:0032525
GO:0032991
GO:0035502
GO:0035846
GO:0035847
GO:0035849
GO:0040019
GO:0043226
GO:0043565
GO:0044344
GO:0045892
GO:0045893
GO:0046872
GO:0048382
GO:0048646
GO:0048703
GO:0048793
GO:0048856
GO:0048870
GO:0060041
GO:0060059
GO:0060065
GO:0060066
GO:0060067
GO:0060068
GO:0060322
GO:0060429
GO:0061205
GO:0072049
GO:0072050
GO:0072077
GO:0072164
GO:0072177
GO:0072178
GO:0072197
GO:0072224
GO:0072278
GO:0072283
GO:0072284
GO:0090009
GO:0090190
GO:0097379
GO:0097477
GO:0140110
GO:1990837
GO:2000543
GO:2000744
GO:2000768
HMNXSV003006969
ILMN_1683405
PH_hs_0025919
TC17000442.hg
TC17000443.hg
TC17002181.hg
g5031866_3p_at
Participates
as an output of
Expression of LHX1 in intermediate mesoderm (Homo sapiens)
Expression of LHX1 (LIM1) in the nephric duct (Homo sapiens)
Expression of LHX1 during nephron development (Homo sapiens)
as an input of
LHX1 binds the NPNT gene (Homo sapiens)
as a component of
LHX1:NPNT gene [nucleoplasm] (Homo sapiens)
This entity regulates
Positively
Expression of EMX2 in the nephric duct
(Homo sapiens)
Expression of PCDH19 in the nephric duct
(Homo sapiens)
Expression of PAX2 in intermediate mesoderm
(Homo sapiens)
Expression of POU3F3 during nephron development
(Homo sapiens)
Expression of DLL1 during nephron development
(Homo sapiens)
Expression of GATA3 in the nephric duct
(Homo sapiens)
Cross References
RefSeq
NP_005559.2
OpenTargets
ENSG00000273706
HPA
ENSG00000273706-LHX1
GeneCards
P48742
Ensembl
ENSP00000484449
,
ENSG00000273706
,
ENST00000620305
,
ENST00000614239
,
ENSP00000477829
,
ENSG00000274577
PRO
P48742
Pharos - Targets
P48742
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9BWG4 SSBP4
0.671
4
UniProt:Q9BWW4 SSBP3
0.569
3
UniProt:Q86U70-2 LDB1
0.556
3
UniProt:Q63ZY3 KANK2
0.556
3
UniProt:Q9BWG6 SCNM1
0.556
3
UniProt:Q53TS8 CTSRT
0.556
5
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text