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GREM1 [extracellular region]
Stable Identifier
R-HSA-9831023
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Gremlin-1, GREM1_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Kidney development (Homo sapiens)
Formation of the ureteric bud (Homo sapiens)
Expression of GREM1 in metanephric mesenchyme (Homo sapiens)
GREM1 [extracellular region] (Homo sapiens)
GREM1 binds BMP4 (Homo sapiens)
GREM1 [extracellular region] (Homo sapiens)
GREM1:BMP4 [extracellular region] (Homo sapiens)
GREM1 [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:O60565 GREM1
Gene Names
GREM1, CKTSF1B1, DAND2, DRM, PIG2
Chain
signal peptide:1-24, chain:25-184
Reference Genes
BioGPS Gene:26585 GREM1
COSMIC (genes):GREM1 GREM1
CTD Gene:26585 GREM1
dbSNP Gene:26585 GREM1
ENSEMBL:ENSG00000166923 GREM1
HGNC:2001 GREM1
KEGG:hsa:26585 GREM1
Monarch:26585 GREM1
NCBI Gene:26585 GREM1
OMIM:603054 GREM1
UCSC:O60565 GREM1
Reference Transcript
RefSeq:NM_001191323.2 GREM1
RefSeq:NM_001368719.1 GREM1
RefSeq:NM_013372.7 GREM1
Other Identifiers
11717065_a_at
11717066_at
11717067_a_at
11758229_s_at
16798951
218468_PM_s_at
218468_s_at
218469_PM_at
218469_at
26585
3587554
3587555
3587556
3587557
3587559
3587560
3587561
3587562
3587563
3587564
3587565
3587566
3587567
3587568
3587569
3587570
3587571
3587572
3587573
3587574
3587575
3587576
3587577
3587578
3587585
39474_s_at
42873_at
50306_at
51995_at
72760_at
77919_at
7982377
A_14_P137758
A_14_P200387
A_23_P432947
A_33_P3319870
GE79962
GO:0000902
GO:0001525
GO:0002042
GO:0002092
GO:0003337
GO:0005125
GO:0005515
GO:0005576
GO:0005615
GO:0006355
GO:0007165
GO:0007267
GO:0008284
GO:0009887
GO:0009954
GO:0009986
GO:0010717
GO:0016015
GO:0030154
GO:0030198
GO:0030199
GO:0030297
GO:0030312
GO:0030326
GO:0030502
GO:0030514
GO:0031012
GO:0032331
GO:0033689
GO:0036122
GO:0038098
GO:0042803
GO:0043066
GO:0043184
GO:0043542
GO:0045668
GO:0045766
GO:0045892
GO:0045893
GO:0045944
GO:0046851
GO:0048018
GO:0048263
GO:0048856
GO:0048870
GO:0051893
GO:0055007
GO:0060173
GO:0060379
GO:0060392
GO:0060676
GO:0090027
GO:0090050
GO:0090090
GO:0090190
GO:0090291
GO:0098772
GO:1900155
GO:1900158
GO:1900748
GO:1901224
HMNXSV003005630
ILMN_1752965
ILMN_2124585
PH_hs_0012703
PH_hs_0028864
TC15000226.hg
g10863087_3p_a_at
g7019348_3p_at
Participates
as an output of
Expression of GREM1 in metanephric mesenchyme (Homo sapiens)
as a component of
GREM1:BMP4 [extracellular region] (Homo sapiens)
as an input of
GREM1 binds BMP4 (Homo sapiens)
Cross References
RefSeq
NP_001178252.1
,
NP_037504.1
,
NP_001355648.1
OpenTargets
ENSG00000166923
ENSEMBL
ENST00000560830
,
ENST00000300177
,
ENSG00000282046
,
ENSP00000498897
,
ENSP00000498763
,
ENSP00000453141
,
ENST00000652365
,
ENST00000651081
,
ENST00000632478
,
ENST00000651154
,
ENSP00000323101
,
ENST00000322805
,
ENSP00000498748
,
ENSP00000488158
,
ENSP00000498605
,
ENSP00000300177
,
ENSG00000276886
,
ENST00000651986
,
ENSG00000166923
HPA
ENSG00000166923-GREM1
GeneCards
GREM1
PRO
O60565
Pharos - Targets
O60565
Orphanet
GREM1
PDB
5AEJ
,
8B7H
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P35968 KDR
5
p-6Y-VEGFR2 [plasma membrane]
(R-HSA-4420103)
VEGFR2 [plasma membrane]
(R-HSA-195382)
p-Y801,Y1054,Y1175-KDR [plasma membrane]
(R-HSA-9860484)
VEGFR2(20-662)insVAGTWTSGLMSL-PDGFRA(471-1089) fusion [plasma membrane]
(R-HSA-9673613)
p-11Y-VEGFR2(20-662)insVAGTWTSGLMSL-PDGFRA(471-1089) [plasma membrane]
(R-HSA-9673636)
0.639
4
UniProt:Q04917 YWHAH
1
YWHAH [cytosol]
(R-HSA-1445107)
0.593
5
UniProt:Q99750 MDFI
0.556
3
UniProt:P59991 KRTAP12-2
1
KRTAP12-2 [cytosol]
(R-HSA-6810271)
0.556
3
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