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p-S69, S73 MITF-M [cytosol]
Stable Identifier
R-HSA-9824966
Type
Genes and Transcripts [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Microphthalmia-associated transcription factor, Class E basic helix-loop-helix protein 32, bHLHe32
Icon
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
MITF-M-regulated melanocyte development (Homo sapiens)
Transcriptional and post-translational regulation of MITF-M expression and activity (Homo sapiens)
XPO1-dependent export of p-S69,S73 MITF-M (Homo sapiens)
p-S69, S73 MITF-M [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O75030-9 MITF
Gene Names
MITF, BHLHE32
Other Identifiers
11720262_a_at
11720263_a_at
1554874_PM_at
1554874_at
207233_PM_s_at
207233_s_at
226066_PM_at
226066_at
2628786
2628787
2628788
2628791
2628792
2628793
2628794
2628800
2628812
2628813
2628816
2628817
2628818
2628834
2628836
2628837
2628838
2628839
2628840
2628841
2628842
2628843
2628845
2628846
2628847
2628848
2628852
2628854
2628855
2628856
2628857
2628858
38227_at
38228_g_at
4286
53198_at
8080938
A_14_P111805
A_14_P112356
A_23_P426663
A_23_P61945
A_23_P73345
A_24_P910310
A_33_P3338733
GE53143
GE56530
GO:0000122
GO:0000785
GO:0000978
GO:0000981
GO:0001227
GO:0001228
GO:0003677
GO:0003682
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005764
GO:0005765
GO:0005773
GO:0005829
GO:0006355
GO:0006357
GO:0010468
GO:0010628
GO:0012501
GO:0016020
GO:0016055
GO:0030154
GO:0030316
GO:0030318
GO:0030336
GO:0032991
GO:0042127
GO:0043010
GO:0043066
GO:0043226
GO:0043473
GO:0045165
GO:0045670
GO:0045893
GO:0045944
GO:0046849
GO:0046983
GO:0048856
GO:0065003
GO:0070888
GO:0140110
GO:1902362
GO:2000144
GO:2001141
HMNXSV003005418
HMNXSV003009100
Hs.5884.0.S1_3p_at
Hs2.344085.1.S1_3p_at
ILMN_1657854
ILMN_1761324
ILMN_2304186
PH_hs_0029291
PH_hs_0030527
TC03000419.hg
Z29678_at
g4557754_3p_a_at
Participates
as an output of
XPO1-dependent export of p-S69,S73 MITF-M (Homo sapiens)
Other forms of this molecule
MITF-M [nucleoplasm]
p-S73 MITF-M [nucleoplasm]
MITF-M [cytosol]
p-S173 MITF-M [cytosol]
Ac-K206 MITF-M [nucleoplasm]
p-S69, S73 MITF-M [nucleoplasm]
monoSUMO1-K182,318 MITF-M [nucleoplasm]
p-S409 MITF-M [nucleoplasm]
p-S397,401,405,409 MITF-M [nucleoplasm]
Inferred To
phospho-hlh-30 [cytosol]
(Caenorhabditis elegans)
phospho-RTG3 [cytosol]
(Saccharomyces cerevisiae)
phospho-Mitf [cytosol]
(Drosophila melanogaster)
phospho-Mitf [cytosol]
(Mus musculus)
phospho-Mitf [cytosol]
(Rattus norvegicus)
phospho-p-S69, S73 MITF-M [cytosol]
(Gallus gallus)
phospho-MITF [cytosol]
(Bos taurus)
phospho-MITF [cytosol]
(Canis familiaris)
phospho-MITF [cytosol]
(Sus scrofa)
Modified Residues
Name
O-phospho-L-serine at 73
Coordinate
73
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 69
Coordinate
69
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
ENSEMBL
ENSP00000324246
,
ENSP00000324443
,
ENST00000314557
,
ENST00000314589
,
ENST00000642352
,
ENST00000448226
,
ENSP00000377880
,
ENSP00000418845
,
ENST00000531774
,
ENSP00000494105
,
ENSP00000391803
,
ENSP00000295600
,
ENSP00000435909
,
ENST00000394351
,
ENST00000352241
,
ENST00000472437
OpenTargets
ENSG00000187098
HPA
ENSG00000187098-MITF
PRO
O75030
Pharos - Targets
O75030
GlyGen
O75030
Orphanet
MITF
PDB
7EOD
,
7D8S
,
7D8R
,
7D8T
,
4C7N
,
8E1D
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P61981 YWHAG
1
YWHAG [cytosol]
(R-HSA-380312)
0.615
3
UniProt:P19484 TFEB
1
TFEB [nucleoplasm]
(R-HSA-9857368)
0.564
3
UniProt:P19532 TFE3
1
TFE3 [nucleoplasm]
(R-HSA-9857366)
0.564
2
UniProt:Q04917 YWHAH
1
YWHAH [cytosol]
(R-HSA-1445107)
0.527
2
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