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TFEB [nucleoplasm]
Stable Identifier
R-HSA-9857368
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
fullName evidence="25"Transcription factor EB, TFEB_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
MITF-M-regulated melanocyte development (Homo sapiens)
MITF-M-dependent gene expression (Homo sapiens)
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence (Homo sapiens)
MITF-M-dependent MCM5 gene expression (Homo sapiens)
MITF dimer [nucleoplasm] (Homo sapiens)
MITF,TFE3,TFEB,TFEC [nucleoplasm] (Homo sapiens)
TFEB [nucleoplasm] (Homo sapiens)
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation (Homo sapiens)
MITF-M-dependent CDC25B gene expression (Homo sapiens)
MITF dimer [nucleoplasm] (Homo sapiens)
MITF,TFE3,TFEB,TFEC [nucleoplasm] (Homo sapiens)
TFEB [nucleoplasm] (Homo sapiens)
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition (Homo sapiens)
MITF-M-dependent CDH1 gene expression (Homo sapiens)
MITF dimer [nucleoplasm] (Homo sapiens)
MITF,TFE3,TFEB,TFEC [nucleoplasm] (Homo sapiens)
TFEB [nucleoplasm] (Homo sapiens)
MITF-M-dependent GXYLT2 gene expression (Homo sapiens)
MITF dimer [nucleoplasm] (Homo sapiens)
MITF,TFE3,TFEB,TFEC [nucleoplasm] (Homo sapiens)
TFEB [nucleoplasm] (Homo sapiens)
MITF-M-dependent SOX2 gene expression (Homo sapiens)
MITF dimer [nucleoplasm] (Homo sapiens)
MITF,TFE3,TFEB,TFEC [nucleoplasm] (Homo sapiens)
TFEB [nucleoplasm] (Homo sapiens)
MITF-M-dependent STT3B gene expression (Homo sapiens)
MITF dimer [nucleoplasm] (Homo sapiens)
MITF,TFE3,TFEB,TFEC [nucleoplasm] (Homo sapiens)
TFEB [nucleoplasm] (Homo sapiens)
MITF-M-dependent ZEB1 gene expression (Homo sapiens)
MITF dimer [nucleoplasm] (Homo sapiens)
MITF,TFE3,TFEB,TFEC [nucleoplasm] (Homo sapiens)
TFEB [nucleoplasm] (Homo sapiens)
Transcriptional and post-translational regulation of MITF-M expression and activity (Homo sapiens)
MITF dimerizes (Homo sapiens)
MITF dimer [nucleoplasm] (Homo sapiens)
MITF,TFE3,TFEB,TFEC [nucleoplasm] (Homo sapiens)
TFEB [nucleoplasm] (Homo sapiens)
MITF,TFE3,TFEB,TFEC [nucleoplasm] (Homo sapiens)
TFEB [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P19484 TFEB
Gene Names
TFEB, BHLHE35
Chain
chain:1-476
Reference Genes
BioGPS Gene:7942 TFEB
COSMIC (genes):TFEB TFEB
CTD Gene:7942 TFEB
dbSNP Gene:7942 TFEB
ENSEMBL:ENSG00000112561 TFEB
HGNC:11753 TFEB
Monarch:7942 TFEB
NCBI Gene:7942 TFEB
OMIM:600744 TFEB
UCSC:P19484 TFEB
Reference Transcript
RefSeq:XM_005249411.1 TFEB
RefSeq:NM_001167827.2 TFEB
RefSeq:NM_001271943.1 TFEB
RefSeq:XM_005249412.1 TFEB
RefSeq:NM_007162.2 TFEB
RefSeq:XM_011514915.1 TFEB
RefSeq:NM_001271945.1 TFEB
RefSeq:NM_001271944.1 TFEB
RefSeq:XM_011514916.2 TFEB
RefSeq:XM_006715213.2 TFEB
RefSeq:XM_006715212.3 TFEB
Other Identifiers
1149_at
11720432_s_at
11747867_s_at
17019077
221866_PM_at
221866_at
2953714
2953715
2953716
2953717
2953718
2953719
2953720
2953721
2953722
2953723
2953724
2953725
2953726
2953727
2953728
2953730
2953731
2953732
2953733
2953734
2953735
2953736
2953741
2953742
2953743
2953744
2953745
2953746
2953747
2953748
2953749
2953750
50221_PM_at
50221_at
7942
8126312
A_23_P368729
A_33_P3344618
A_33_P3398634
GE56126
GO:0000785
GO:0000976
GO:0000978
GO:0000981
GO:0001892
GO:0002250
GO:0002376
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0005737
GO:0005764
GO:0005765
GO:0005773
GO:0005829
GO:0006355
GO:0006357
GO:0006914
GO:0006959
GO:0007040
GO:0009267
GO:0010508
GO:0016020
GO:0019899
GO:0032418
GO:0034198
GO:0043226
GO:0045893
GO:0045944
GO:0046983
GO:0048856
GO:0098542
GO:0140110
GO:0140367
GO:1990837
HMNXSV003001167
Hs.23391.0.S1_3p_s_at
ILMN_1733616
PH_hs_0002059
PH_hs_0031080
TC06003646.hg
p26873
Participates
as a member of
MITF,TFE3,TFEB,TFEC [nucleoplasm] (Homo sapiens)
Cross References
OpenTargets
ENSG00000112561
ENSEMBL
ENSP00000412551
,
ENST00000445214
,
ENST00000230323
,
ENSP00000393874
,
ENST00000420312
,
ENSP00000396168
,
ENST00000424495
,
ENSP00000406491
,
ENST00000403298
,
ENSP00000343948
,
ENSP00000230323
,
ENSP00000362124
,
ENST00000419396
,
ENST00000373033
,
ENSP00000502927
,
ENST00000343317
,
ENST00000416140
,
ENST00000419574
,
ENST00000677531
,
ENSP00000383998
,
ENST00000406563
,
ENSP00000400276
,
ENSP00000503069
,
ENSP00000410391
,
ENSP00000384203
,
ENST00000678831
HPA
ENSG00000112561-TFEB
PRO
P19484
Pharos - Targets
P19484
GlyGen
P19484
PDB
7UX2
,
7Y62
,
7UXH
,
7UXC
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P62258 YWHAE
1
YWHAE [cytosol]
(R-HSA-194368)
0.744
5
UniProt:O75030 MITF
2
monoSUMO1-K289,423-MITF [nucleoplasm]
(R-HSA-3232153)
MITF [nucleoplasm]
(R-HSA-201592)
0.564
3
UniProt:P63104 YWHAZ
2
YWHAZ [cytosol]
(R-HSA-206099)
YWHAZ [nucleoplasm]
(R-HSA-450469)
0.527
4
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