IRF7 is phosphorylated on Ser477 and Ser479 residues [Lin R et al 2000] . IRAK1[Uematsu et al 2005] and IKK alpha[Hoshino et al 2006] are thought to mediate the phosphorylation upon TLR7/8/9 activation.
Takeuchi, O, Yamamoto, M, Matsuda, M, Ishii, KJ, Sato, S, Akira, S, Kawai, T, Kato, H, Coban, C, Hirotani, T, Uematsu, S, Takeshita, F
MariƩ, I, Prakash, A, Smith, E, Levy, DE
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