IRF7:TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane]

Stable Identifier
Homo sapiens
Related Species
Influenza A virus, Human immunodeficiency virus 1, Human SARS coronavirus
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
15492225 Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling

Honda, K, Yanai, H, Mizutani, T, Negishi, H, Shimada, N, Suzuki, N, Ohba, Y, Takaoka, A, Yeh, WC, Taniguchi, T

Proc Natl Acad Sci U S A 2004
15361868 Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

Kawai, T, Sato, S, Ishii, KJ, Coban, C, Hemmi, H, Yamamoto, M, Terai, K, Matsuda, M, Inoue, J, Uematsu, S, Takeuchi, O, Akira, S

Nat Immunol 2004
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