Reactome | AKAP12 [plasma membrane]

AKAP12 [plasma membrane]

Stable Identifier

R-HSA-9715082

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q02952 AKAP12

Gene Names

AKAP12, AKAP250

Chain

initiator methionine:, chain:2-1782

Reference Genes

BioGPS Gene:9590 AKAP12

COSMIC (genes):AKAP12 AKAP12

CTD Gene:9590 AKAP12

dbSNP Gene:9590 AKAP12

ENSEMBL:ENSG00000131016 AKAP12

ENSEMBL_homo_sapiens_GENE:ENSG00000131016.17 AKAP12

HGNC:370 AKAP12

KEGG Gene (Homo sapiens):9590 AKAP12

Monarch:9590 AKAP12

NCBI Gene:9590 AKAP12

OMIM:604698 AKAP12

UCSC:Q02952 AKAP12

Reference Transcript

Other Identifiers

11723804_a_at

11723805_a_at

17013773

210517_PM_s_at

210517_s_at

227529_PM_s_at

227529_s_at

227530_PM_at

227530_at

2931570

2931572

2931573

2931574

2931602

2931613

2931614

2931620

2931621

2931626

2931627

2931628

2931629

2931630

2931631

2931632

2931633

2931634

2931635

2931636

2931637

2931638

2931640

2931641

2931642

37680_at

49825_at

8122807

82404_s_at

82406_r_at

9590

A_14_P125086

A_23_P111311

A_23_P214897

A_32_P152437

GE500750

GO:0003013

GO:0005515

GO:0005516

GO:0005737

GO:0005829

GO:0005856

GO:0005886

GO:0005925

GO:0005938

GO:0007165

GO:0007186

GO:0007193

GO:0008179

GO:0010738

GO:0010739

GO:0012501

GO:0016020

GO:0023052

GO:0032496

GO:0032760

GO:0035733

GO:0043025

GO:0043116

GO:0043226

GO:0048870

GO:0050804

GO:0051018

GO:0051602

GO:0051770

GO:0061870

GO:0070374

GO:0071347

GO:0071356

GO:0090036

GO:0098685

GO:1900143

HMNXSV003028266

Hs.38022.0.A1_3p_at

ILMN_1684836

ILMN_1686846

ILMN_1715532

ILMN_2308950

PH_hs_0022958

TC06001100.hg

U81607_at

g2081606_3p_a_at

Participates

as a candidate of

Inferred To

Akap12 [plasma membrane] (Mus musculus)

Akap12 [plasma membrane] (Rattus norvegicus)

akap12 [plasma membrane] (Xenopus tropicalis)

AKAP12 [plasma membrane] (Bos taurus)

AKAP12 [plasma membrane] (Canis familiaris)

AKAP12 [plasma membrane] (Gallus gallus)

AKAP12 [plasma membrane] (Sus scrofa)

Cross References

RefSeq

XP_016867006.1, NP_653080.1, NP_005091.2, XP_005267292.1

OpenTargets

ENSG00000131016

HPA

ENSG00000131016-AKAP12

GeneCards

Q02952

Ensembl

ENSG00000131016, ENSP00000346702, ENSP00000384537, ENSP00000352794, ENST00000253332, ENST00000354675, ENST00000402676, ENSP00000253332, ENST00000359755

PRO

Q02952

Pharos - Targets

Q02952

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.635	3
UniProt:P13861 PRKAR2A	2	PRKAR2A [cytosol] (R-HSA-57840) PRKAR2A [ciliary base] (R-HSA-5610412)	0.564	2
UniProt:P35222 CTNNB1	20	CTNNB1 S45A [cytosol] (R-HSA-9663982) CTNNB1 S45F [cytosol] (R-HSA-4791268) CTNNB1 S45C [cytosol] (R-HSA-9663983) CTNNB1 S45Y [cytosol] (R-HSA-9663975) CTNNB1 S45N [cytosol] (R-HSA-9663984) CTNNB1 S45P [cytosol] (R-HSA-4791272) pT41,S45-CTNNB1 S37P [cytosol] (R-HSA-9663981) pT41,S45-CTNNB1 S37F [cytosol] (R-HSA-4839621) pT41,S45-CTNNB1 S37A [cytosol] (R-HSA-4839619) pT41,S45-CTNNB1 S37Y [cytosol] (R-HSA-9663978) pT41,S45-CTNNB1 S37C [cytosol] (R-HSA-4839617) pS37,T41,S45-CTNNB1 S33A [cytosol] (R-HSA-9663976) pS37,T41,S45-CTNNB1 S33T [cytosol] (R-HSA-9663977) pS37,T41,S45-CTNNB1 S33C [cytosol] (R-HSA-4839630) pS37,T41,S45-CTNNB1 S33F [cytosol] (R-HSA-4839628) pS37,T41,S45-CTNNB1 S33P [cytosol] (R-HSA-4839626) pS37,T41,S45-CTNNB1 S33Y [cytosol] (R-HSA-4839625) pS45-CTNNB1 T41N [cytosol] (R-HSA-9663980) pS45-CTNNB1 T41A [cytosol] (R-HSA-4836868) pS45-CTNNB1 T41I [cytosol] (R-HSA-4839612)	0.564	2
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	11

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