ATP2B1 (PMCA1) transports Ca2+ from the cytosol to the extracellular region

Stable Identifier
R-HSA-9664214
Type
Reaction
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
ATP2B1 (PMCA1) transports Ca2+ from the cytosol to the extracellular region
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

ATP2B1 (PMCA1) located in the basolateral membrane of inner hair cells transports calcium ions from the cytosol to the extracellular region with concomitant hydrolysis of ATP (inferred from the rat homolog). The efflux of calcium ions is believed to participate in repolarization of the cell.

Participants
Input
Output
Participates
as an event of
Catalyst Activity

P-type calcium transporter activity of ATP2B1 [plasma membrane]

Physical Entity
ATP2B1 [plasma membrane] (Homo sapiens)
Activity
P-type calcium transporter activity (GO:0005388)
Inferred From
Atp2b1 (Pmca1) transports Ca2+ from the cytosol to the extracellular region (Rattus norvegicus)
Cross References
Rhea
Authored
May, B  (2019-10-21)
Reviewed
Furness, DN  (2020-09-13)
Created
May, B  (2019-10-22)
Cite Us!