ATP2B1 (PMCA1) transports Ca2+ from the cytosol to the extracellular region

Stable Identifier
R-HSA-9664214
Type
Reaction [transition]
Species
Homo sapiens
Compartment
plasma membrane
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ATP2B1 (PMCA1) transports Ca2+ from the cytosol to the extracellular region
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ATP2B1 (PMCA1) located in the basolateral membrane of inner hair cells transports calcium ions from the cytosol to the extracellular region with concomitant hydrolysis of ATP (inferred from the rat homolog). The efflux of calcium ions is believed to participate in repolarization of the cell.

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Catalyst Activity

calcium transmembrane transporter activity, phosphorylative mechanism of ATP2B1 [plasma membrane]

Physical Entity
ATP2B1 [plasma membrane] (Homo sapiens)
Activity
calcium transmembrane transporter activity, phosphorylative mechanism (GO:0005388)
Inferred From
Atp2b1 (Pmca1) transports Ca2+ from the cytosol to the extracellular region (Rattus norvegicus)
Authored
May, B  (2019-10-21)
Reviewed
Furness, DN  (2020-09-14)
Created
May, B  (2019-10-22)
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