ATP2B1 (PMCA1) transports Ca2+ from the cytosol to the extracellular region

Stable Identifier
R-HSA-9664214
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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ATP2B1 (PMCA1) located in the basolateral membrane of inner hair cells transports calcium ions from the cytosol to the extracellular region with concomitant hydrolysis of ATP (inferred from the rat homolog). The efflux of calcium ions is believed to participate in repolarization of the cell.

Participants
Participates
Catalyst Activity

calcium transmembrane transporter activity, phosphorylative mechanism of ATP2B1 [plasma membrane]

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