STAT5 Activation

Stable Identifier
R-HSA-9645135
Type
Pathway
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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STAT5 Activation
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Signal transducer and activator of transcription (STAT) constitutes a family of universal transcription factors. STAT5 refers to two highly related proteins, STAT5A and STAT5B, with critical function in cell survival and proliferation. Several upstream signals including cytokines and growth factors can trigger STAT5 activation.
Literature References
PubMed ID Title Journal Year
23103841 The protein tyrosine phosphatase, Shp2, positively contributes to FLT3-ITD-induced hematopoietic progenitor hyperproliferation and malignant disease in vivo

Boswell, HS, Ramdas, B, Feng, GS, Zeng, L, Kapur, R, He, Y, Liu, Z, Zhang, X, Sandusky, GE, Zhang, ZY, Fukuda, S, Li, XJ, Nabinger, SC, Yu, M, Richine, B, Chan, RJ, Goenka, S, Bowling, JD

Leukemia 2013
Participants
Events
Participates
as an event of
Event Information
Go Biological Process
response to cytokine (0034097)
Cross References
BioModels Database
Authored
Varusai, TM  (2019-02-23)
Reviewed
Traer, E  (2019-05-03)
Joshi, S  (2019-05-21)
Created
Varusai, TM  (2019-05-04)
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