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MUTYH-6 [nucleoplasm]
Stable Identifier
R-HSA-9606668
Type
Genes and Transcripts [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
MUTYH gamma-3 isoform
Locations in the PathwayBrowser
Expand all
DNA Repair (Homo sapiens)
Base Excision Repair (Homo sapiens)
Base-Excision Repair, AP Site Formation (Homo sapiens)
Depurination (Homo sapiens)
Cleavage of the damaged purine (Homo sapiens)
Cleavage of adenine mispaired with 8-oxoguanine by MUTYH (Homo sapiens)
MUTYH:(8oxoG:Ade)-dsDNA [nucleoplasm] (Homo sapiens)
MUTYH [nucleoplasm] (Homo sapiens)
MUTYH-6 [nucleoplasm] (Homo sapiens)
MUTYH:AP-dsDNA [nucleoplasm] (Homo sapiens)
MUTYH [nucleoplasm] (Homo sapiens)
MUTYH-6 [nucleoplasm] (Homo sapiens)
Recognition and association of DNA glycosylase with site containing an affected purine (Homo sapiens)
MUTYH mediated recognition and binding of an adenine opposite to an 8-oxoguanine (Homo sapiens)
MUTYH [nucleoplasm] (Homo sapiens)
MUTYH-6 [nucleoplasm] (Homo sapiens)
MUTYH:(8oxoG:Ade)-dsDNA [nucleoplasm] (Homo sapiens)
MUTYH [nucleoplasm] (Homo sapiens)
MUTYH-6 [nucleoplasm] (Homo sapiens)
Resolution of Abasic Sites (AP sites) (Homo sapiens)
Displacement of DNA glycosylase by APEX1 (Homo sapiens)
Displacement of MUTYH glycosylase by APEX1 at the AP site (Homo sapiens)
MUTYH [nucleoplasm] (Homo sapiens)
MUTYH-6 [nucleoplasm] (Homo sapiens)
MUTYH:AP-dsDNA [nucleoplasm] (Homo sapiens)
MUTYH [nucleoplasm] (Homo sapiens)
MUTYH-6 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UIF7-6 MUTYH
Gene Names
MUTYH, MYH
Other Identifiers
0007000102
11734568_a_at
16686401
207727_PM_s_at
207727_s_at
2410112
2410113
2410120
2410123
2410124
2410126
2410127
2410128
2410130
2410131
2410133
2410134
2410135
2410137
2410139
2410141
2410142
2410143
2410144
2410145
2410147
2410149
2410150
2410151
2410152
2410153
4595
489_at
490_g_at
7915695
A_23_P51660
A_24_P910898
GE80793
GO:0000701
GO:0003677
GO:0003824
GO:0005515
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005739
GO:0006281
GO:0006284
GO:0006298
GO:0006950
GO:0006974
GO:0008152
GO:0012501
GO:0016787
GO:0016798
GO:0019104
GO:0032357
GO:0032407
GO:0034039
GO:0035485
GO:0043226
GO:0045007
GO:0046872
GO:0051536
GO:0051539
GO:0060546
GO:0140097
HMNXSV003054539
ILMN_2277537
ILMN_2336970
PH_hs_0013965
TC01002607.hg
U63329_at
g6912519_3p_a_at
Participates
as a member of
MUTYH [nucleoplasm] (Homo sapiens)
Other forms of this molecule
MUTYH-6 L360P [nucleoplasm]
MUTYH-6 R154H [nucleoplasm]
MUTYH-6 E452del [nucleoplasm]
MUTYH-6 P377L [nucleoplasm]
MUTYH-6 I195V [nucleoplasm]
MUTYH-6 M255V [nucleoplasm]
MUTYH-6 Y151C [nucleoplasm]
MUTYH-6 G368D [nucleoplasm]
Inferred To
MUTYH [nucleoplasm]
(Bos taurus)
MUTYH [nucleoplasm]
(Gallus gallus)
MUTYH [nucleoplasm]
(Sus scrofa)
MUTYH-6 [nucleoplasm]
(Canis familiaris)
MUTYH-6 [nucleoplasm]
(Mus musculus)
MUTYH-6 [nucleoplasm]
(Plasmodium falciparum)
MUTYH-6 [nucleoplasm]
(Rattus norvegicus)
MUTYH-6 [nucleoplasm]
(Schizosaccharomyces pombe)
mutyh [nucleoplasm]
(Danio rerio)
mutyh [nucleoplasm]
(Xenopus tropicalis)
MYH [nucleoplasm]
(Dictyostelium discoideum)
Cross References
RefSeq
NP_001280121.1
,
NP_001280119.1
,
NP_001041638.1
,
NP_036354.1
,
NP_001280120.1
,
XP_016856824.1
,
NP_001121897.1
,
NP_001041639.1
,
NP_001041637.1
,
XP_016856823.1
,
NP_001280124.1
,
NP_001041636.1
,
NP_001280125.1
,
XP_011539806.1
OpenTargets
ENSG00000132781
GeneCards
Q9UIF7
HPA
ENSG00000132781-MUTYH
Ensembl
ENSP00000500891
,
ENSP00000346354
,
ENST00000372098
,
ENSP00000347685
,
ENSP00000361182
,
ENSP00000361176
,
ENST00000456914
,
ENSP00000361170
,
ENSP00000361187
,
ENST00000372110
,
ENST00000354383
,
ENST00000355498
,
ENSP00000409718
,
ENSG00000132781
,
ENST00000372115
,
ENSP00000407590
,
ENST00000448481
,
ENST00000372104
,
ENST00000672818
PRO
Q9UIF7
Pharos - Targets
Q9UIF7
Orphanet
16490
PDB
1X51
,
3N5N
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