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p-PIK3AP1 (p-BCAP) binds PIK3CD:PIK3R1 (PI3K delta)
Stable Identifier
R-HSA-9606160
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
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Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Signaling by the B Cell Receptor (BCR) (Homo sapiens)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Homo sapiens)
p-PIK3AP1 (p-BCAP) binds PIK3CD:PIK3R1 (PI3K delta) (Homo sapiens)
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Phosphorylated PIK3AP1 (BCAP) binds the p85 subunit of phosphoinositide 3-kinase (PI3K) (inferred from chicken homologs). PIK3AP1 is phosphorylated by LYN in response to activation of CD19.
Participants
Input
p-4Y-PIK3AP1 [plasma membrane]
(Homo sapiens)
PIK3CD:PIK3R1 [cytosol]
(Homo sapiens)
Output
BCAP Signalosome [plasma membrane]
(Homo sapiens)
Participates
as an event of
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Homo sapiens)
Inferred From
PIK3AP1 (BCAP) binds PIK3CD:PIK3R1 (Gallus gallus)
Authored
May, B (2018-04-14)
Reviewed
Wienands, J (2018-07-18)
Created
May, B (2018-04-19)
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