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BCAP Signalosome [plasma membrane]
Stable Identifier
R-HSA-2045909
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
p-PIK3AP1:PIK3CD:PIK3R1, p-BCAP:PI3K delta
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
PI3K/AKT Signaling in Cancer (Homo sapiens)
Constitutive Signaling by Aberrant PI3K in Cancer (Homo sapiens)
PI3K inhibitors block PI3K catalytic activity (Homo sapiens)
PI3K Inhibitors:PI3K [cytosol] (Homo sapiens)
PI3K mutants,Activator:PI3K [plasma membrane] (Homo sapiens)
Activator:PI3K [plasma membrane] (Homo sapiens)
BCAP Signalosome [plasma membrane] (Homo sapiens)
PI3K mutants,Activator:PI3K [plasma membrane] (Homo sapiens)
Activator:PI3K [plasma membrane] (Homo sapiens)
BCAP Signalosome [plasma membrane] (Homo sapiens)
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Signaling by the B Cell Receptor (BCR) (Homo sapiens)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Homo sapiens)
BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 (Homo sapiens)
BCAP Signalosome [plasma membrane] (Homo sapiens)
p-PIK3AP1 (p-BCAP) binds PIK3CD:PIK3R1 (PI3K delta) (Homo sapiens)
BCAP Signalosome [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Intracellular signaling by second messengers (Homo sapiens)
PIP3 activates AKT signaling (Homo sapiens)
Negative regulation of the PI3K/AKT network (Homo sapiens)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Homo sapiens)
PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
Activator:PI3K [plasma membrane] (Homo sapiens)
BCAP Signalosome [plasma membrane] (Homo sapiens)
PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
Activator:PI3K [plasma membrane] (Homo sapiens)
BCAP Signalosome [plasma membrane] (Homo sapiens)
Participants
components
p-4Y-PIK3AP1 [plasma membrane]
(Homo sapiens)
PIK3CD:PIK3R1 [plasma membrane]
(Homo sapiens)
Participates
as an output of
p-PIK3AP1 (p-BCAP) binds PIK3CD:PIK3R1 (PI3K delta) (Homo sapiens)
as a member of
Activator:PI3K [plasma membrane] (Homo sapiens)
Inferred To
BCAP Signalosome [plasma membrane]
(Bos taurus)
BCAP Signalosome [plasma membrane]
(Canis familiaris)
BCAP Signalosome [plasma membrane]
(Danio rerio)
BCAP Signalosome [plasma membrane]
(Drosophila melanogaster)
BCAP Signalosome [plasma membrane]
(Gallus gallus)
BCAP Signalosome [plasma membrane]
(Mus musculus)
BCAP Signalosome [plasma membrane]
(Rattus norvegicus)
BCAP Signalosome [plasma membrane]
(Sus scrofa)
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