Reactome | UBE2F [cytosol]

UBE2F [cytosol]

Stable Identifier

R-HSA-947635

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

NEDD8-conjugating enzyme UBE2F, UBE2F_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q969M7 UBE2F

Gene Names

UBE2F, NCE2

Chain

chain:1-185

Reference Genes

BioGPS Gene:140739 UBE2F

COSMIC (genes):UBE2F UBE2F

CTD Gene:140739 UBE2F

dbSNP Gene:140739 UBE2F

ENSEMBL:ENSG00000184182 UBE2F

HGNC:12480 UBE2F

KEGG:hsa:140739 UBE2F

Monarch:140739 UBE2F

NCBI Gene:140739 UBE2F

OMIM:617700 UBE2F

UCSC:Q969M7 UBE2F

Reference Transcript

Other Identifiers

11739398_a_at

11739399_s_at

11754036_s_at

11754037_x_at

11756751_x_at

11757677_x_at

11763178_at

11763179_s_at

11763180_x_at

140739

225783_PM_at

225783_at

225787_PM_at

225787_at

225791_PM_at

225791_at

231948_PM_s_at

231948_s_at

238507_PM_at

238507_at

2534566

2534567

2534568

2534569

2534570

2534573

2534574

2534576

2534577

2534578

2534579

2534581

2534582

2534586

2534588

2534589

2534592

2534593

2534594

2534595

2534596

2534602

2534603

2534604

2534606

2534608

2534610

2534612

3895421

43153_at

49056_at

49057_g_at

57184_at

8049574

A_14_P111866

A_14_P121935

A_23_P39561

GE78959

GE87718

GO:0000166

GO:0000209

GO:0002376

GO:0003824

GO:0004842

GO:0005515

GO:0005524

GO:0005634

GO:0005829

GO:0016740

GO:0019788

GO:0030163

GO:0043161

GO:0043687

GO:0045087

GO:0045116

GO:0051607

GO:0061654

GO:0061663

GO:0098542

GO:0140096

HMNXSV003008100

Hs.189746.0.A1_3p_at

Hs.289051.0.A1_3p_a_at

Hs.289051.0.A1_3p_x_at

Hs.289051.0.A2_3p_at

Hs.289051.0.A3_3p_at

Hs.289051.1.S1_3p_a_at

ILMN_2164242

PH_hs_0011117

PH_hs_0022726

TC02005014.hg

Participates

as a candidate of

E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)

Other forms of this molecule

AcM-UBE2F [cytosol]

G76-NEDD8-C116-AcM-UBE2F [cytosol]

Inferred To

ubc12 [cytosol] (Schizosaccharomyces pombe)

ube2m [cytosol] (Dictyostelium discoideum)

UBE2F [cytosol] (Bos taurus)

UBE2F [cytosol] (Canis familiaris)

UBE2F [cytosol] (Gallus gallus)

UBE2F [cytosol] (Plasmodium falciparum)

Ube2f [cytosol] (Mus musculus)

Ube2f [cytosol] (Rattus norvegicus)

UBC12 [cytosol] (Saccharomyces cerevisiae)

ube2f [cytosol] (Danio rerio)

Cross References

RefSeq

NP_001265236.1, NP_001265235.1, NP_542409.1, NP_001265234.1, NP_001265237.1

ENSEMBL

ENSP00000387299, ENSP00000393515, ENST00000409953, ENSP00000409749, ENST00000433241, ENST00000441728, ENSP00000386680, ENST00000612130, ENSP00000478474, ENSG00000184182, ENSP00000399183, ENSP00000272930, ENST00000414443, ENST00000272930, ENST00000409633

OpenTargets

ENSG00000184182

GeneCards

UBE2F

HPA

ENSG00000184182-UBE2F

PRO

Q969M7

Pharos - Targets

Q969M7

HMDB Protein

HMDBP09265

PDB

4GBA, 2EDI, 3FN1

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P26367 PAX6	1	PAX6 [nucleoplasm] (R-HSA-3009044)	0.556	3
UniProt:P80188 LCN2	2	LCN2 [extracellular region] (R-HSA-5215934) LCN2 [specific granule lumen] (R-HSA-6799614)	0.556	3
UniProt:P62879 GNB2	4	GNB2 [cytosol] (R-HSA-6814421) Partially folded GNB2 [cytosol] (R-HSA-8850536) Unfolded GNB2 [cytosol] (R-HSA-6814202) GNB2 [plasma membrane] (R-HSA-164335)	0.556	3