Reactome | UBE2F [cytosol]

UBE2F [cytosol]

Stable Identifier

R-HSA-947635

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

NEDD8-conjugating enzyme UBE2F, UBE2F_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q969M7 UBE2F

Gene Names

UBE2F, NCE2

Chain

chain:1-185

Reference Genes

BioGPS Gene:140739 UBE2F

COSMIC (genes):UBE2F UBE2F

CTD Gene:140739 UBE2F

dbSNP Gene:140739 UBE2F

ENSEMBL:ENSG00000184182 UBE2F

ENSEMBL_homo_sapiens_GENE:ENSG00000184182.19 UBE2F

HGNC:12480 UBE2F

KEGG Gene (Homo sapiens):140739 UBE2F

Monarch:140739 UBE2F

NCBI Gene:140739 UBE2F

OMIM:617700 UBE2F

UCSC:Q969M7 UBE2F

Reference Transcript

Other Identifiers

11739398_a_at

11739399_s_at

11754037_x_at

11756751_x_at

11757677_x_at

11763178_at

11763179_s_at

11763180_x_at

140739

225783_PM_at

225783_at

225787_PM_at

225787_at

225791_PM_at

225791_at

231948_PM_s_at

231948_s_at

2534566

2534567

2534573

2534577

2534579

2534586

2534589

2534592

2534596

2534602

2534603

2534604

3895421

49056_at

49057_g_at

57184_at

8049574

A_14_P111866

A_14_P121935

GE78959

GE87718

GO:0000166

GO:0003824

GO:0005515

GO:0005524

GO:0005634

GO:0005829

GO:0016740

GO:0019787

GO:0019788

GO:0032446

GO:0036211

GO:0043226

GO:0043687

GO:0045116

GO:0061654

GO:0061663

GO:0140096

HMNXSV003008100

Hs.289051.0.A1_3p_a_at

Hs.289051.0.A1_3p_x_at

Hs.289051.0.A2_3p_at

Hs.289051.0.A3_3p_at

Hs.289051.1.S1_3p_a_at

ILMN_2164242

PH_hs_0022726

TC02005014.hg

Participates

as a candidate of

E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)

Other forms of this molecule

G76-NEDD8-C116-AcM-UBE2F [cytosol]

AcM-UBE2F [cytosol]

Inferred To

ubc12 [cytosol] (Schizosaccharomyces pombe)

ube2m [cytosol] (Dictyostelium discoideum)

UBE2F [cytosol] (Bos taurus)

UBE2F [cytosol] (Canis familiaris)

UBE2F [cytosol] (Gallus gallus)

UBE2F [cytosol] (Plasmodium falciparum)

Ube2f [cytosol] (Mus musculus)

Ube2f [cytosol] (Rattus norvegicus)

UBC12 [cytosol] (Saccharomyces cerevisiae)

ube2f [cytosol] (Danio rerio)

Cross References

RefSeq

NP_001265237.1, NP_001265234.1, NP_001265236.1, NP_542409.1, NP_001265235.1

OpenTargets

ENSG00000184182

GeneCards

Q969M7

HPA

ENSG00000184182-UBE2F

Ensembl

ENSP00000409749, ENST00000409953, ENSP00000386680, ENST00000272930, ENSG00000184182, ENST00000409633, ENST00000612130, ENSP00000478474, ENSP00000272930, ENSP00000387299, ENST00000441728, ENST00000433241, ENSP00000393515, ENST00000414443, ENSP00000399183

PRO

Q969M7

Pharos - Targets

Q969M7

PDB

4GBA, 3FN1, 2EDI

HMDB Protein

HMDBP09265

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P26367 PAX6	1	PAX6 [nucleoplasm] (R-HSA-3009044)	0.556	3
UniProt:P62879 GNB2	4	GNB2 [cytosol] (R-HSA-6814421) Partially folded GNB2 [cytosol] (R-HSA-8850536) Unfolded GNB2 [cytosol] (R-HSA-6814202) GNB2 [plasma membrane] (R-HSA-164335)	0.556	3
UniProt:P80188 LCN2	2	LCN2 [specific granule lumen] (R-HSA-6799614) LCN2 [extracellular region] (R-HSA-5215934)	0.556	3