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OTUB2 [cytosol]
Stable Identifier
R-HSA-933410
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Ubiquitin thioesterase OTUB2, OTUB2_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Deubiquitination (Homo sapiens)
Ovarian tumor domain proteases (Homo sapiens)
OTUB1, (OTUB2) binds RNF128, TRAF3, TRAF6, RHOA (Homo sapiens)
OTUB1,(OTUB2) [cytosol] (Homo sapiens)
OTUB2 [cytosol] (Homo sapiens)
OTUB1,(OTUB2):RNF128,TRAF3,TRAF6,RHOA,TP53 [cytosol] (Homo sapiens)
OTUB1,(OTUB2) [cytosol] (Homo sapiens)
OTUB2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96DC9 OTUB2
Gene Names
OTUB2, C14orf137, OTB2, OTU2
Chain
chain:1-234
Reference Genes
BioGPS Gene:78990 OTUB2
COSMIC (genes):OTUB2 OTUB2
CTD Gene:78990 OTUB2
dbSNP Gene:78990 OTUB2
ENSEMBL:ENSG00000089723 OTUB2
ENSEMBL_homo_sapiens_GENE:ENSG00000089723.10 OTUB2
ENSEMBL_homo_sapiens_GENE:ENSG00000277276.3 OTUB2
HGNC:20351 OTUB2
KEGG Gene (Homo sapiens):78990 OTUB2
Monarch:78990 OTUB2
NCBI Gene:78990 OTUB2
OMIM:608338 OTUB2
UCSC:Q96DC9 OTUB2
Reference Transcript
RefSeq:NM_023112.3 OTUB2
Other Identifiers
11725831_at
11725832_s_at
11753488_a_at
1555682_3p_at
1555682_PM_at
1555682_at
16787790
219369_PM_s_at
219369_s_at
222878_PM_s_at
222878_s_at
240550_PM_at
240550_at
3549518
3549523
3549524
3549525
3549526
3549527
3549528
3549529
3549530
3549531
3549533
3549535
3549537
3549539
3549541
47154_at
49127_at
75947_at
78990
7976425
A_14_P103762
A_23_P65386
A_24_P124875
A_24_P124879
GE82749
GO:0003824
GO:0004843
GO:0005515
GO:0005634
GO:0006281
GO:0006508
GO:0008233
GO:0008234
GO:0016579
GO:0016787
GO:0035871
GO:0036211
GO:0043130
GO:0043226
GO:0070536
GO:0071108
GO:0140096
GO:2000780
HMNXSV003013299
HMNXSV003043594
Hs.117295.0.A1_3p_at
Hs.90034.0.S1_3p_a_at
Hs2.90034.2.A1_3p_at
Hs2.90034.2.A1_3p_s_at
ILMN_1684983
ILMN_1792012
ILMN_1799198
PH_hs_0023404
TC14000582.hg
g12962938_3p_a_at
Participates
as a candidate of
OTUB1,(OTUB2) [cytosol] (Homo sapiens)
Other forms of this molecule
OTUB2 [nucleoplasm]
Inferred To
otub2 [cytosol]
(Xenopus tropicalis)
Otub2 [cytosol]
(Mus musculus)
Otub2 [cytosol]
(Rattus norvegicus)
OTUB2 [cytosol]
(Bos taurus)
OTUB2 [cytosol]
(Caenorhabditis elegans)
OTUB2 [cytosol]
(Canis familiaris)
OTUB2 [cytosol]
(Drosophila melanogaster)
OTUB2 [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_075601.1
OpenTargets
ENSG00000089723
GeneCards
Q96DC9
HPA
ENSG00000089723-OTUB2
Ensembl
ENSG00000089723
,
ENSP00000478628
,
ENST00000553723
,
ENST00000617748
,
ENST00000628711
,
ENSG00000277276
,
ENSP00000203664
,
ENSP00000451283
,
ENSP00000487491
,
ENST00000203664
PRO
Q96DC9
Pharos - Targets
Q96DC9
PDB
5QIY
,
5QIP
,
5QIU
,
5QIX
,
5QIT
,
8CMS
,
5QIO
,
5QIS
,
5QIW
,
5QIV
,
5QIZ
,
5QIR
,
4FJV
,
1TFF
,
5QIQ
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P54252 ATXN3
2
ATXN3 [nucleoplasm]
(R-HSA-6783285)
ATXN3 [cytosol]
(R-HSA-5625607)
0.556
9
UniProt:Q9UHC7 MKRN1
2
MKRN1 [cytosol]
(R-HSA-976042)
p-S109-MKRN1 [cytosol]
(R-HSA-8948758)
0.556
3
UniProt:Q9Y4K3 TRAF6
8
K48polyUb-TRAF6 [cytosol]
(R-HSA-6783233)
PolyUb-TRAF6 [cytosol]
(R-HSA-6782845)
TRAF6 [endosome membrane]
(R-HSA-450272)
K63polyUb-TRAF6 [endosome membrane]
(R-HSA-450227)
TRAF6 [cytosol]
(R-HSA-166366)
K63polyUb-TRAF6 [cytosol]
(R-HSA-2685681)
K63polyUb-TRAF6 [plasma membrane]
(R-HSA-936980)
TRAF6 [plasma membrane]
(R-HSA-936955)
0.556
3
UniProt:Q8IUQ4 SIAH1
1
SIAH1 [cytosol]
(R-HSA-374563)
0.556
3
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