Reactome | MICU2 [mitochondrial inner membrane]

MICU2 [mitochondrial inner membrane]

Stable Identifier

R-HSA-8949166

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

Calcium uptake protein 2, mitochondrial, MICU2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8IYU8 MICU2

Gene Names

MICU2, EFHA1

Chain

transit peptide:1-22, chain:23-434

Reference Genes

BioGPS Gene:221154 MICU2

COSMIC (genes):MICU2 MICU2

CTD Gene:221154 MICU2

dbSNP Gene:221154 MICU2

ENSEMBL:ENSG00000165487 MICU2

ENSEMBL_homo_sapiens_GENE:ENSG00000165487.14 MICU2

HGNC:31830 MICU2

KEGG Gene (Homo sapiens):221154 MICU2

Monarch:221154 MICU2

NCBI Gene:221154 MICU2

OMIM:610632 MICU2

UCSC:Q8IYU8 MICU2

Reference Transcript

RefSeq:NM_152726.2 MICU2

Other Identifiers

11717683_s_at

16777334

212410_PM_at

212410_at

221154

3504792

3504793

3504794

3504796

3504798

3504799

3504803

3504807

3504808

3504809

3504817

3504819

3504825

3504826

3504834

3504835

3504843

3504844

38102_at

7970546

A_23_P76598

GE85833

GO:0005509

GO:0005515

GO:0005739

GO:0005743

GO:0005758

GO:0006851

GO:0034704

GO:0036444

GO:0043226

GO:0046982

GO:0051560

GO:0051561

GO:0051562

GO:0055065

GO:0055085

GO:1990246

HMNXSV003018300

Hs.75188.0.S1_3p_at

ILMN_1738346

TC13000474.hg

Participates

as a member of

Inferred To

MICU2 [mitochondrial inner membrane] (Bos taurus)

MICU2 [mitochondrial inner membrane] (Caenorhabditis elegans)

MICU2 [mitochondrial inner membrane] (Canis familiaris)

MICU2 [mitochondrial inner membrane] (Dictyostelium discoideum)

MICU2 [mitochondrial inner membrane] (Gallus gallus)

MICU2 [mitochondrial inner membrane] (Sus scrofa)

MICU3 [mitochondrial inner membrane] (Drosophila melanogaster)

Micu2 [mitochondrial inner membrane] (Mus musculus)

Micu2 [mitochondrial inner membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_689939.1

OpenTargets

ENSG00000165487

HPA

ENSG00000165487-MICU2

GeneCards

Q8IYU8

Ensembl

ENST00000382374, ENSG00000165487, ENSP00000371811

PRO

Q8IYU8

Pharos - Targets

Q8IYU8

HMDB Protein

HMDBP07664

PDB

6XQN, 6LE5, 6AGH, 6WDO, 6XJX, 6XQO, 6LB7, 6IIH, 6LB8, 6WDN, 6K7Y, 6XJV

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9BPX6 MICU1	1	MICU1 [mitochondrial inner membrane] (R-HSA-8949180)	0.641	5
UniProt:Q8NE86 MCU	1	MCU [mitochondrial inner membrane] (R-HSA-8949184)	0.527	3
UniProt:Q9H4I9 SMDT1	3	SMDT1 transit peptide [mitochondrial matrix] (R-HSA-8949642) SMDT1 [mitochondrial inner membrane] (R-HSA-8949227) proSMDT1 [mitochondrial inner membrane] (R-HSA-8949655)	0.488	3