Reactome | TRA2B [nucleoplasm]

TRA2B [nucleoplasm]

Stable Identifier

R-HSA-8850859

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Transformer-2 protein homolog beta, TRA2B_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P62995 TRA2B

Gene Names

TRA2B, SFRS10

Chain

initiator methionine:1, chain:2-288

Reference Genes

BioGPS Gene:6434 TRA2B

COSMIC (genes):TRA2B TRA2B

CTD Gene:6434 TRA2B

dbSNP Gene:6434 TRA2B

ENSEMBL:ENSG00000136527 TRA2B

HGNC:10781 TRA2B

KEGG Gene (Homo sapiens):6434 TRA2B

Monarch:6434 TRA2B

NCBI Gene:6434 TRA2B

OMIM:602719 TRA2B

UCSC:P62995 TRA2B

Reference Transcript

Other Identifiers

0002470148

11734662_a_at

11734663_at

11746041_a_at

11746042_s_at

11746043_x_at

11753944_a_at

11753945_x_at

11753975_x_at

11756318_x_at

11757832_s_at

140_s_at

16962359

200892_s_at

200893_at

210180_3p_s_at

210180_s_at

239447_at

2709072

2709073

2709074

2709075

2709076

2709077

2709078

2709079

2709081

2709084

2709086

2709087

2709089

2709091

2709092

2709093

2709095

2709096

2709101

2709102

2709112

2709113

2709114

2709115

6434

70770_at

74923_at

8092564

A_23_P212639

A_24_P145911

A_33_P3297517

GE59355

GE710350

GO:0000302

GO:0000375

GO:0000381

GO:0000398

GO:0003674

GO:0003676

GO:0003723

GO:0003729

GO:0005515

GO:0005575

GO:0005622

GO:0005623

GO:0005634

GO:0005635

GO:0005637

GO:0005654

GO:0005681

GO:0005737

GO:0006397

GO:0006950

GO:0008150

GO:0008380

GO:0009790

GO:0019904

GO:0021796

GO:0032991

GO:0034641

GO:0036002

GO:0042592

GO:0042802

GO:0043226

GO:0043484

GO:0048026

GO:0048471

GO:0048856

GO:0051252

GO:0071333

GO:1990403

GO:1990904

Hs.133257.0.A1_3p_at

ILMN_1742798

PH_hs_0039988

TC03002080.hg

U68063_at

g12653362_3p_s_at

g2367403_3p_at

g2367403_3p_s_at

g4759097_3p_at

Participant Of

input

Lariat Formation and 5'-Splice Site Cleavage

hasComponent

Inferred To

tra2 [nucleoplasm] (Drosophila melanogaster)

Tra2b [nucleoplasm] (Mus musculus)

Tra2b [nucleoplasm] (Rattus norvegicus)

TRA2B [nucleoplasm] (Bos taurus)

TRA2B [nucleoplasm] (Canis familiaris)

TRA2B [nucleoplasm] (Dictyostelium discoideum)

TRA2B [nucleoplasm] (Gallus gallus)

TRA2B [nucleoplasm] (Sus scrofa)

rsp-8 [nucleoplasm] (Caenorhabditis elegans)

tra2b [nucleoplasm] (Danio rerio)

tra2b [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

XP_005247760.1, XP_016862522.1, NP_001230808.1, XP_011511374.1, NP_004584.1

OpenTargets

ENSG00000136527

HPA

ENSG00000136527-TRA2B

GeneCards

P62995

Ensembl

ENST00000456380, ENSP00000416959, ENSP00000343857, ENSG00000136527, ENST00000342294, ENST00000382191, ENST00000453386, ENSP00000371626, ENSP00000416887

PRO

P62995

PDB

2CQC, 2RRB, 2RRA, 2KXN

Interactors (18)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P78362 SRPK2			0.683	4
UniProt:P38159 RBMX	1	RBMX [nucleoplasm] (R-HSA-71939)	0.666	4
UniProt:Q08170 SRSF4	1	SRSF4 [nucleoplasm] (R-HSA-72024)	0.666	4
UniProt:P49761 CLK3			0.666	7
UniProt:Q96MU7 YTDC1			0.666	4
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.589	2
UniProt:P63104 YWHAZ	2	YWHAZ [cytosol] (R-HSA-206099) YWHAZ [nucleoplasm] (R-HSA-450469)	0.589	2
UniProt:P62995 TRA2B	1	TRA2B [nucleoplasm] (R-HSA-8850859)	0.556	3
UniProt:Q9Y5E9 PCDBE			0.556	3
UniProt:Q7L775 EPMIP			0.556	3
UniProt:Q86VE0 MYPOP			0.556	3
UniProt:P0DN76 U2AF5			0.556	3
UniProt:P49759-3 CLK1			0.556	5
UniProt:Q9BRL6-2 SRSF8			0.556	3
UniProt:Q96A72 MAGOHB	1	MAGOHB [nucleoplasm] (R-HSA-8867888)	0.556	3
UniProt:Q15415 RBY1F			0.556	3
UniProt:Q13242 SRSF9	1	SRSF9 [nucleoplasm] (R-HSA-72037)	0.556	3
UniProt:Q07955 SRSF1	1	SRSF1 [nucleoplasm] (R-HSA-72031)	0.556	3