Reactome | POLR3E [nucleoplasm]

POLR3E [nucleoplasm]

Stable Identifier

R-HSA-83706

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

HsRPC5, DNA-directed RNA polymerases III 80 kDa polypeptide , RNA polymerase III subunit 5, RPC5

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9NVU0 POLR3E

Gene Names

POLR3E, KIAA1452

Chain

chain:1-708

Reference Genes

BioGPS Gene:55718 POLR3E

COSMIC (genes):POLR3E POLR3E

CTD Gene:55718 POLR3E

dbSNP Gene:55718 POLR3E

ENSEMBL:ENSG00000058600 POLR3E

HGNC:30347 POLR3E

KEGG:hsa:55718 POLR3E

Monarch:55718 POLR3E

NCBI Gene:55718 POLR3E

OMIM:617815 POLR3E

UCSC:Q9NVU0 POLR3E

Reference Transcript

Other Identifiers

11735359_a_at

16816833

218016_PM_s_at

218016_s_at

222490_PM_at

222490_at

233458_PM_at

233458_at

2845016

2900716

2947615

3527576

3652488

3652490

3652491

3652492

3652493

3652494

3652495

3652496

3652497

3652498

3652499

3652500

3652501

3652502

3652503

3652504

3652505

3652506

3652507

3652508

3652509

3652512

3652513

3652514

3652515

3652516

3652517

3652518

3652519

3652520

3652521

3652522

3652523

3652524

3652525

3652526

3652527

3652528

3652530

3652531

3652532

3652533

3652534

3652535

3652545

55718

65574_at

7993973

90472_at

A_14_P117749

A_14_P118395

A_23_P152181

A_23_P385529

A_33_P3286041

GE86545

GO:0000428

GO:0002376

GO:0005634

GO:0005654

GO:0005666

GO:0005829

GO:0006351

GO:0006399

GO:0042797

GO:0043226

GO:0045087

GO:0051607

GO:0098542

HMNXSV003050520

Hs.274319.1.S1_3p_at

Hs.274319.1.S1_3p_x_at

PH_hs_0029851

PH_hs_0037726

TC05001073.hg

TC05001078.hg

TC05002154.hg

TC05002158.hg

TC06000307.hg

TC06001476.hg

TC14000060.hg

TC16000244.hg

TC16000245.hg

g8922476_3p_a_at

Participates

as a component of

HsRPC4:HsRPC5 [nucleoplasm] (Homo sapiens)

Other forms of this molecule

POLR3E [cytosol]

Inferred To

rpc5 [nucleoplasm] (Dictyostelium discoideum)

Polr3e [nucleoplasm] (Mus musculus)

Polr3e [nucleoplasm] (Rattus norvegicus)

Polr3E [nucleoplasm] (Drosophila melanogaster)

POLR3E [nucleoplasm] (Bos taurus)

POLR3E [nucleoplasm] (Canis familiaris)

POLR3E [nucleoplasm] (Gallus gallus)

POLR3E [nucleoplasm] (Sus scrofa)

polr3e [nucleoplasm] (Xenopus tropicalis)

Ghost homologue of POLR3E [nucleoplasm] (Saccharomyces cerevisiae)

Ghost homologue of POLR3E [nucleoplasm] (Schizosaccharomyces pombe)

Cross References

RefSeq

NP_001244965.1, NP_001244964.1, NP_001244962.1, NP_001244963.1, XP_006726676.1, XP_006721126.1, NP_060589.1

OpenTargets

ENSG00000058600

ENSEMBL

ENST00000299853, ENSP00000492263, ENST00000564209, ENSP00000399254, ENSP00000492514, ENST00000359210, ENSP00000456967, ENSP00000352140, ENSP00000299853, ENST00000418581, ENST00000640588, ENST00000639550

HPA

ENSG00000058600-POLR3E

PRO

Q9NVU0

Pharos - Targets

Q9NVU0

GlyGen

Q9NVU0

HMDB Protein

HMDBP11925

PDB

8IUE, 7A6H, 8ITY, 7FJJ, 7AE1, 7ASU, 7AE3, 7FJI, 7AEA, 7D59, 7ASV, 7AST, 7D58, 7DN3, 7DU2, 8IUH

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P19388 POLR2E	2	POLR2E [cytosol] (R-HSA-1964438) POLR2E [nucleoplasm] (R-HSA-83713)	0.825	7
UniProt:O15160 POLR1C	2	POLR1C [cytosol] (R-HSA-1964454) POLR1C [nucleoplasm] (R-HSA-63498)	0.643	5
UniProt:P61218 POLR2F	2	POLR2F [cytosol] (R-HSA-1964441) POLR2F [nucleoplasm] (R-HSA-83714)	0.643	6
UniProt:Q9H063 MAF1	3	p-S60,S68,S75-MAF1 [cytosol] (R-HSA-8944455) MAF1 [cytosol] (R-HSA-8944460) MAF1 [nucleoplasm] (R-HSA-8944422)	0.527	2
UniProt:P62875 POLR2L	2	POLR2L [cytosol] (R-HSA-1964467) POLR2L [nucleoplasm] (R-HSA-83715)	0.527	3
UniProt:P53803 POLR2K	2	POLR2K [cytosol] (R-HSA-1964445) POLR2K [nucleoplasm] (R-HSA-63537)	0.527	3

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