Reactome | POLR2F [cytosol]

POLR2F [cytosol]

Stable Identifier

R-HSA-1964441

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

HsRPABC2, DNA-directed RNA polymerase II 14.4 kDa polypeptide (EC 2.7.7.6) (RPB6) (RPB14.4), DNA-directed RNA polymerase II 14.4 kDa polypeptide , RPB6, RPB14.4, RPABC2

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P61218 POLR2F

Gene Names

POLR2F, POLRF

Chain

initiator methionine:, chain:2-127

Reference Genes

BioGPS Gene:5435 POLR2F

COSMIC (genes):POLR2F POLR2F

CTD Gene:5435 POLR2F

dbSNP Gene:5435 POLR2F

ENSEMBL:ENSG00000100142 POLR2F

HGNC:9193 POLR2F

KEGG:hsa:5435 POLR2F

Monarch:5435 POLR2F

NCBI Gene:5435 POLR2F

OMIM:604414 POLR2F

UCSC:P61218 POLR2F

Reference Transcript

RefSeq:NM_021974.4 POLR2F

Other Identifiers

11720324_a_at

11720325_at

16930021

209511_PM_at

209511_at

232643_PM_at

232643_at

36027_at

3945134

3945135

3945136

3945137

3945138

3945141

3945142

3945143

3945144

3945145

3945146

3945147

3945148

3945149

3945150

3945152

3945153

3945157

3945158

3945159

3945177

5435

8072979

A_21_P0010416

A_23_P80321

A_24_P417007

A_33_P3318960

A_33_P3318963

A_33_P3371460

A_33_P3383561

GE593235

GE60383

GE780585

GO:0000428

GO:0001054

GO:0001055

GO:0001056

GO:0001650

GO:0003677

GO:0003824

GO:0003899

GO:0005634

GO:0005654

GO:0005665

GO:0005666

GO:0005730

GO:0005736

GO:0005829

GO:0006351

GO:0006360

GO:0006366

GO:0006399

GO:0016740

GO:0042797

GO:0043226

GO:0140098

HMNXSV003015228

HMNXSV003017910

HMNXSV003024448

HMNXSV003026557

HMNXSV003045070

HMNXSV003046870

HMNXSV003048936

HMNXSV003050554

Hs.287709.0.S1_3p_at

ILMN_1745885

PH_hs_0003285

PH_hs_0014904

PH_hs_0037675

RNA95738|RNS_820_118

TC22000295.hg

Z27113_at

g13097770_3p_at

g13097770_3p_x_at

p21802

p21803

p25233

Participates

as a component of

RNA Polymerase III Holoenzyme [cytosol] (Homo sapiens)

Other forms of this molecule

POLR2F [nucleoplasm]

Cross References

OpenTargets

ENSG00000100142

ENSEMBL

ENSG00000100142, ENST00000442738, ENSP00000403852

GeneCards

POLR2F

HPA

ENSG00000100142-POLR2F

PRO

P61218

Pharos - Targets

P61218

HMDB Protein

HMDBP11912

PDB

7FJJ, 7FJI, 7AE1, 7A6H, 7DU2, 7AE3, 8IUH, 8A43, 6XRE, 7DTI, 7DTH, 7LBM, 1QKL, 6DRD, 5IYD, 5IYC, 8ITY, 7DN3, 7D58, 6O9L, 7OB9, 7D59, 7AEA, 7AST, 8IUE, 7OBB, 5IY6, 7OBA, 7VBA, 5IY9, 5IYB, 5IYA, 5IY7, 7VBC, 7VBB, 5IY8

Interactors (42)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P19388 POLR2E	2	POLR2E [cytosol] (R-HSA-1964438) POLR2E [nucleoplasm] (R-HSA-83713)	0.867	11
UniProt:O95602 POLR1A	1	POLR1A [nucleoplasm] (R-HSA-63494)	0.643	6
UniProt:Q9H9Y6 POLR1B	1	POLR1B [nucleoplasm] (R-HSA-63496)	0.643	5
UniProt:O15160 POLR1C	2	POLR1C [cytosol] (R-HSA-1964454) POLR1C [nucleoplasm] (R-HSA-63498)	0.643	6
UniProt:Q9H1D9 POLR3F	2	POLR3F [cytosol] (R-HSA-1964434) POLR3F [nucleoplasm] (R-HSA-83708)	0.643	6
UniProt:P0DPB6 RPAC2			0.643	4
UniProt:Q9BUI4 POLR3C	2	POLR3C [cytosol] (R-HSA-1964448) POLR3C [nucleoplasm] (R-HSA-1964430)	0.643	5
UniProt:O14802 POLR3A	2	POLR3A [cytosol] (R-HSA-1964433) POLR3A [nucleoplasm] (R-HSA-83700)	0.643	5
UniProt:O15514 POLR2D	1	POLR2D [nucleoplasm] (R-HSA-63508)	0.643	5
UniProt:Q9Y535 POLR3H	2	POLR3H [cytosol] (R-HSA-1964440) POLR3H [nucleoplasm] (R-HSA-83710)	0.643	5
UniProt:Q9Y2Y1 POLR3K	2	POLR3K [nucleoplasm] (R-HSA-1964461) POLR3K [cytosol] (R-HSA-1964455)	0.643	5
UniProt:P05423 POLR3D	2	POLR3D [nucleoplasm] (R-HSA-83704) POLR3D [cytosol] (R-HSA-1964429)	0.643	5
UniProt:O15446 POLR1G	1	CD3EAP [nucleoplasm] (R-HSA-5419289)	0.643	5
UniProt:Q9NVU0 POLR3E	2	POLR3E [cytosol] (R-HSA-1964451) POLR3E [nucleoplasm] (R-HSA-83706)	0.643	6
UniProt:P19387 POLR2C	1	POLR2C [nucleoplasm] (R-HSA-63506)	0.643	5
UniProt:P52435 POLR2J	1	POLR2J [nucleoplasm] (R-HSA-63531)	0.643	6
UniProt:O75575 CRCP	2	CRCP [cytosol] (R-HSA-5420849) CRCP [nucleoplasm] (R-HSA-5420844)	0.643	5
UniProt:Q9BT43 POLR3GL	2	POLR3GL [nucleoplasm] (R-HSA-1964458) POLR3GL [cytosol] (R-HSA-1964463)	0.643	5
UniProt:P36954 POLR2I	1	POLR2I [nucleoplasm] (R-HSA-63525)	0.643	5
UniProt:P24928 POLR2A	7	POLR2A [nucleoplasm] (R-HSA-63502) p-S2,S5(CTD)-POLR2A [nucleoplasm] (R-HSA-113420) p-S5(CTD)-POLR2A [nucleoplasm] (R-HSA-77100) p-3S-POLR2A [nucleoplasm] (R-HSA-6797701) Ub,p-S2,S5(CTD)-POLR2A [nucleoplasm] (R-HSA-6781855) p-S5,S7(CTD)-POLR2A [nucleoplasm] (R-HSA-6810226) p-S2,S7(CTD)-POLR2A [nucleoplasm] (R-HSA-6814543)	0.643	5
UniProt:Q9NW08 POLR3B	2	POLR3B [cytosol] (R-HSA-1964435) POLR3B [nucleoplasm] (R-HSA-83702)	0.643	6
UniProt:P62487 POLR2G	1	POLR2G [nucleoplasm] (R-HSA-63517)	0.643	5
UniProt:P52434 POLR2H	2	POLR2H [cytosol] (R-HSA-1964450) POLR2H [nucleoplasm] (R-HSA-63523)	0.527	4
UniProt:O00267 SUPT5H	1	p-SUPT5H [nucleoplasm] (R-HSA-3009372)	0.527	2
UniProt:O95402 MED26	1	MED26 [nucleoplasm] (R-HSA-556783)	0.527	3
UniProt:Q9P1U0 POLR1H	1	ZNRD1 [nucleoplasm] (R-HSA-5419292)	0.527	2
UniProt:Q8IXW5 RPAP2	1	RPAP2 [nucleoplasm] (R-HSA-6810227)	0.527	4
UniProt:Q9Y5B0 CTDP1	1	CTDP1 [nucleoplasm] (R-HSA-113416)	0.527	2
UniProt:Q00403 GTF2B	1	GTF2B [nucleoplasm] (R-HSA-65888)	0.527	2
UniProt:A0JLT2 MED19	1	MED19 [nucleoplasm] (R-HSA-556819)	0.527	2
UniProt:O15318 POLR3G	2	POLR3G [nucleoplasm] (R-HSA-1964459) POLR3G [cytosol] (R-HSA-1964446)	0.527	4
UniProt:Q9HCN4 GPN1			0.527	4
UniProt:O94762 RECQ5			0.527	4
UniProt:Q8N7H5 PAF1	1	PAF1 [nucleoplasm] (R-HSA-8866689)	0.527	2
UniProt:Q9GZS1 POLR1E	1	POLR1E [nucleoplasm] (R-HSA-5419294)	0.527	5
UniProt:P62875 POLR2L	2	POLR2L [cytosol] (R-HSA-1964467) POLR2L [nucleoplasm] (R-HSA-83715)	0.527	4
UniProt:Q7KZ85 SUPT6H	1	SUPT6H [nucleoplasm] (R-HSA-8932908)	0.527	3
UniProt:P30876 POLR2B	1	POLR2B [nucleoplasm] (R-HSA-63504)	0.527	4
UniProt:Q9UHW5 GPN3			0.527	2
UniProt:Q9NQG5 RPRD1B	1	RPRD1B [nucleoplasm] (R-HSA-6814894)	0.527	4
UniProt:P35269 GTF2F1	1	GTF2F1 [nucleoplasm] (R-HSA-65565)	0.527	2
UniProt:Q8WV16 DCAF4	1	DCAF4 [nucleoplasm] (R-HSA-8955191)	0.527	3

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