Reactome | GLUD1 [mitochondrial matrix]

GLUD1 [mitochondrial matrix]

Stable Identifier

R-HSA-70582

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

Glutamate dehydrogenase 1, mitochondrial precursor

Locations in the PathwayBrowser

Expand all

Literature References

PubMed ID	Title	Journal	Year
429360	Partial amino acid sequence of the glutamate dehydrogenase of human liver and a revision of the sequence of the bovine enzyme Julliard, JH, Smith, EL	J Biol Chem	1979

External Reference Information

External Reference

UniProt:P00367 GLUD1

Gene Names

GLUD1, GLUD

Chain

transit peptide:1-53, chain:54-558

Reference Genes

BioGPS Gene:2746 GLUD1

COSMIC (genes):GLUD1 GLUD1

CTD Gene:2746 GLUD1

dbSNP Gene:2746 GLUD1

ENSEMBL:ENSG00000148672 GLUD1

ENSEMBL_homo_sapiens_GENE:ENSG00000148672.10 GLUD1

HGNC:4335 GLUD1

KEGG Gene (Homo sapiens):2746 GLUD1

Monarch:2746 GLUD1

NCBI Gene:2746 GLUD1

OMIM:138130 GLUD1

UCSC:P00367 GLUD1

Reference Transcript

Other Identifiers

11716206_a_at

11716207_s_at

11716208_s_at

11750168_x_at

16716239

200946_PM_x_at

200946_x_at

200947_PM_s_at

200947_s_at

215794_PM_x_at

215794_x_at

2746

31691_g_at

3244888

3244901

3244940

3245067

3245599

3245601

3245616

3251816

3251843

3298978

3298979

3298980

3298981

3298982

3298983

3298984

3298987

3298988

3298989

3298992

3298995

3298998

3299002

3299007

3299008

3299009

3299011

3299017

3299019

3299020

3299023

3299024

3299025

3299026

3299027

3299028

37341_at

3989261

3989262

3989263

4038067

4038068

4038069

4038359

4038367

4038368

4038371

4038374

7934852

A_23_P138665

GE57862

GO:0000166

GO:0003824

GO:0004352

GO:0004353

GO:0004354

GO:0005515

GO:0005524

GO:0005525

GO:0005737

GO:0005739

GO:0005759

GO:0005783

GO:0006520

GO:0006537

GO:0006538

GO:0006541

GO:0016491

GO:0016639

GO:0021762

GO:0023052

GO:0032024

GO:0042803

GO:0043226

GO:0043531

GO:0048856

GO:0070403

GO:0070728

GO:0072350

HMNXSV003052737

Hs.272497.1.S1_3p_s_at

Hs.77508.0.A1_3p_a_at

Hs.77508.0.A1_3p_x_at

ILMN_1713756

M20867_s_at

PH_hs_0023977

TC10001486.hg

g4885280_3p_a_at

Participates

as a member of

Other forms of this molecule

Ack-GLUD1 [mitochondrial matrix]

RibC-GLUD1 [mitochondrial matrix]

Inferred To

glud1b [mitochondrial matrix] (Danio rerio)

GLUD1 [mitochondrial matrix] (Bos taurus)

GLUD1 [mitochondrial matrix] (Caenorhabditis elegans)

GLUD1 [mitochondrial matrix] (Canis familiaris)

GLUD1 [mitochondrial matrix] (Dictyostelium discoideum)

GLUD1 [mitochondrial matrix] (Drosophila melanogaster)

GLUD1 [mitochondrial matrix] (Mus musculus)

GLUD1 [mitochondrial matrix] (Rattus norvegicus)

GLUD1 [mitochondrial matrix] (Sus scrofa)

GLUD1 [mitochondrial matrix] (Xenopus tropicalis)

Homologues of GLUD1 [mitochondrial matrix] (Sus scrofa)

GLUD2 [mitochondrial matrix] (Gallus gallus)

Cross References

RefSeq

NP_001305835.1, NP_001305831.1, NP_005262.1, NP_001305830.1, NP_001305833.1, NP_001305834.1, NP_001305829.1

OpenTargets

ENSG00000148672

GeneCards

P00367

HPA

ENSG00000148672-GLUD1

Ensembl

ENSP00000507881, ENSP00000277865, ENSP00000508244, ENSG00000148672, ENSP00000507316, ENSP00000508107, ENSP00000508098, ENST00000681988, ENST00000684372, ENST00000684546, ENST00000682507, ENST00000277865, ENST00000683783, ENST00000683256, ENSP00000507901, ENST00000683269, ENSP00000507729

PRO

P00367

Pharos - Targets

P00367

Orphanet

16145

HMDB Protein

HMDBP00694

PDB

7UZM, 8W4J, 1L1F, 6DQG, 8KGY, 1NR1, 8SK8

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13418 ILK	1	ILK [cytosol] (R-HSA-432864)	0.527	2
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	7

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