Reactome | MCM10 [nucleoplasm]

MCM10 [nucleoplasm]

Stable Identifier

R-HSA-68403

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Mcm10

Locations in the PathwayBrowser for interactor UniProt:Q9Y2I6 NINL

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External Reference Information

External Reference

UniProt:Q7L590 MCM10

Gene Names

MCM10, PRO2249

Chain

chain:1-875

Reference Genes

BioGPS Gene:55388 MCM10

COSMIC - genes:MCM10 MCM10

CTD Gene:55388 MCM10

dbSNP Gene:55388 MCM10

ENSEMBL:ENSG00000065328 MCM10

HGNC:18043 MCM10

KEGG:hsa:55388 MCM10

Monarch:55388 MCM10

NCBI Gene:55388 MCM10

OMIM:609357 MCM10

UCSC:Q7L590 MCM10

Reference Transcript

Participates

as an input of

Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Homo sapiens)

as a component of

Inferred To

mcm-10 [nucleoplasm] (Caenorhabditis elegans)

MCM10 [nucleoplasm] (Bos taurus)

MCM10 [nucleoplasm] (Danio rerio)

MCM10 [nucleoplasm] (Drosophila melanogaster)

MCM10 [nucleoplasm] (Gallus gallus)

MCM10 [nucleoplasm] (Mus musculus)

MCM10 [nucleoplasm] (Saccharomyces cerevisiae)

MCM10 [nucleoplasm] (Schizosaccharomyces pombe)

MCM10 [nucleoplasm] (Sus scrofa)

Mcm10 [nucleoplasm] (Rattus norvegicus)

Ghost homologue of MCM10 [nucleoplasm] (Canis familiaris)

Ghost homologue of MCM10 [nucleoplasm] (Dictyostelium discoideum)

Ghost homologue of MCM10 [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

XP_054222210.1, XP_011517840.1, NP_877428.1, XP_054222209.1, NP_060988.3, XP_047281393.1

ENSEMBL

ENSP00000418268, ENSP00000367986, ENST00000484800, ENST00000378714, ENSG00000065328

OpenTargets

ENSG00000065328

GeneCards

MCM10

HPA

ENSG00000065328-MCM10

PRO

Q7L590

Pharos - Targets

Q7L590

GlyGen

Q7L590

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13416 ORC2	1	ORC2 [nucleoplasm] (R-HSA-68405)	0.715	5
UniProt:Q14566 MCM6	1	MCM6 [nucleoplasm] (R-HSA-68553)	0.693	3
UniProt:Q9P209 CEP72	1	CEP72 [cytosol] (R-HSA-380321)	0.553	2
UniProt:O94972 TRIM37	1	TRIM37 [cytosol] (R-HSA-976049)	0.553	2
UniProt:P02792 FTL	4	FTL [cytosol] (R-HSA-434215) FTL [azurophil granule lumen] (R-HSA-6799149) FTL [extracellular region] (R-HSA-2187214) FTL [endocytic vesicle lumen] (R-HSA-2299671)	0.527	3
UniProt:Q9UL42 PNMA2			0.527	2
UniProt:Q7L590 MCM10	1	MCM10 [nucleoplasm] (R-HSA-68403)	0.522	2
UniProt:Q9Y2I6 NINL	2	p-NINL [cytosol] (R-HSA-380716) NINL [cytosol] (R-HSA-380706)	0.519	2

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