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POU2F2 [nucleoplasm]
Stable Identifier
R-HSA-6814932
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
POU domain, class 2, transcription factor 2, PO2F2_HUMAN
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
RNA polymerase II transcribes snRNA genes (Homo sapiens)
CBCAP complex binds 7-methylguanosine cap of snRNA (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
POU2F2 [nucleoplasm] (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
POU2F2 [nucleoplasm] (Homo sapiens)
CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Homo sapiens)
RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
POU2F2 [nucleoplasm] (Homo sapiens)
RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
POU2F2 [nucleoplasm] (Homo sapiens)
Dephosphorylation and dissociation of RNA polymerase II at 3' end of snRNA gene (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
POU2F2 [nucleoplasm] (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
POU2F2 [nucleoplasm] (Homo sapiens)
General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
POU2F2 [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
POU2F2 [nucleoplasm] (Homo sapiens)
Integrator complex processes the 3' end of snRNA (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
POU2F2 [nucleoplasm] (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
POU2F2 [nucleoplasm] (Homo sapiens)
POU2F1 (OCT1) or POU2F2 (OCT2), SP1, and ZNF143 (STAF) bind the DSE of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
POU2F2 [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
POU2F2 [nucleoplasm] (Homo sapiens)
Pre-snRNA is elongated and capped with 7-methylguanosine (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
POU2F2 [nucleoplasm] (Homo sapiens)
RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
POU2F2 [nucleoplasm] (Homo sapiens)
Pre-snRNA transcript initiation, Integrator binding, LEC binding (Homo sapiens)
RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
POU2F2 [nucleoplasm] (Homo sapiens)
RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
POU2F2 [nucleoplasm] (Homo sapiens)
RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
POU2F2 [nucleoplasm] (Homo sapiens)
RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
POU2F2 [nucleoplasm] (Homo sapiens)
RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Homo sapiens)
RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
POU2F2 [nucleoplasm] (Homo sapiens)
RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
POU2F2 [nucleoplasm] (Homo sapiens)
SNAPc binds PSE of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
POU2F2 [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
POU2F2 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P09086 POU2F2
Gene Names
POU2F2, OCT2, OTF2
Chain
chain:1-479
Reference Genes
BioGPS Gene:5452 POU2F2
COSMIC (genes):POU2F2 POU2F2
CTD Gene:5452 POU2F2
dbSNP Gene:5452 POU2F2
ENSEMBL:ENSG00000028277 POU2F2
HGNC:9213 POU2F2
KEGG:hsa:5452 POU2F2
Monarch:5452 POU2F2
NCBI Gene:5452 POU2F2
OMIM:164176 POU2F2
UCSC:P09086 POU2F2
Reference Transcript
RefSeq:NM_001247994.3 POU2F2
RefSeq:NM_001207025.4 POU2F2
RefSeq:NM_001207026.3 POU2F2
RefSeq:NM_002698.6 POU2F2
Participates
as a member of
POU2F1,2 [nucleoplasm] (Homo sapiens)
Inferred To
Pou2f2 [nucleoplasm]
(Mus musculus)
Pou2f2 [nucleoplasm]
(Rattus norvegicus)
nub [nucleoplasm]
(Drosophila melanogaster)
POU2F2 [nucleoplasm]
(Bos taurus)
POU2F2 [nucleoplasm]
(Canis familiaris)
POU2F2 [nucleoplasm]
(Sus scrofa)
pou2f2 [nucleoplasm]
(Xenopus tropicalis)
Cross References
RefSeq
NP_001234923.1
,
NP_001193955.1
,
NP_001193954.1
,
NP_002689.1
ENSEMBL
ENST00000526816
,
ENST00000529067
,
ENST00000529952
,
ENSP00000437224
,
ENSP00000436988
,
ENSP00000431603
,
ENST00000389341
,
ENSG00000028277
,
ENSP00000373992
OpenTargets
ENSG00000028277
GeneCards
POU2F2
HPA
ENSG00000028277-POU2F2
ZINC target
P09086
PRO
P09086
Pharos - Targets
P09086
GlyGen
P09086
PDB
9DZM
,
1HDP
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