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POU2F1,2 [nucleoplasm]
Stable Identifier
R-HSA-6814929
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Oct-1,Oct-2
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
RNA polymerase II transcribes snRNA genes (Homo sapiens)
CBCAP complex binds 7-methylguanosine cap of snRNA (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Homo sapiens)
RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
Dephosphorylation and dissociation of RNA polymerase II at 3' end of snRNA gene (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
Integrator complex processes the 3' end of snRNA (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
POU2F1 (OCT1) or POU2F2 (OCT2), SP1, and ZNF143 (STAF) bind the DSE of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
Pre-snRNA is elongated and capped with 7-methylguanosine (Homo sapiens)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
Pre-snRNA transcript initiation, Integrator binding, LEC binding (Homo sapiens)
RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Homo sapiens)
RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Homo sapiens)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
SNAPc binds PSE of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Homo sapiens)
POU2F1,2 [nucleoplasm] (Homo sapiens)
Participants
members
POU2F1 [nucleoplasm] (Homo sapiens)
POU2F2 [nucleoplasm] (Homo sapiens)
Participant Of
input
POU2F1 (OCT1) or POU2F2 (OCT2), SP1, and ZNF143 (STAF) bind the DSE of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12)
hasComponent
POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm]
Inferred To
POU2F1,2 [nucleoplasm] (Bos taurus)
POU2F1,2 [nucleoplasm] (Canis familiaris)
POU2F1,2 [nucleoplasm] (Danio rerio)
POU2F1,2 [nucleoplasm] (Mus musculus)
POU2F1,2 [nucleoplasm] (Rattus norvegicus)
POU2F1,2 [nucleoplasm] (Xenopus tropicalis)
Ghost homologue of POU2F1,2 [nucleoplasm] (Caenorhabditis elegans)
Ghost homologue of POU2F1,2 [nucleoplasm] (Dictyostelium discoideum)
Ghost homologue of POU2F1,2 [nucleoplasm] (Drosophila melanogaster)
Ghost homologue of POU2F1,2 [nucleoplasm] (Gallus gallus)
Ghost homologue of POU2F1,2 [nucleoplasm] (Saccharomyces cerevisiae)
Ghost homologue of POU2F1,2 [nucleoplasm] (Schizosaccharomyces pombe)
Ghost homologue of POU2F1,2 [nucleoplasm] (Sus scrofa)
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