Reactome | Pou2f2 [nucleoplasm]

Pou2f2 [nucleoplasm]

Stable Identifier

R-MMU-6814932

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

POU2F2, Q00196

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Mus musculus)

- RNA Polymerase II Transcription (Mus musculus)
  - RNA polymerase II transcribes snRNA genes (Mus musculus)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2 [nucleoplasm] (Mus musculus)
        
        Pou2f2 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2 [nucleoplasm] (Mus musculus)
        
        Pou2f2 [nucleoplasm] (Mus musculus)
    - CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Mus musculus)
      - RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2 [nucleoplasm] (Mus musculus)
        
        Pou2f2 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2 [nucleoplasm] (Mus musculus)
        
        Pou2f2 [nucleoplasm] (Mus musculus)
    - General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene (Mus musculus)
      - Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2 [nucleoplasm] (Mus musculus)
        
        Pou2f2 [nucleoplasm] (Mus musculus)
      - SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2 [nucleoplasm] (Mus musculus)
        
        Pou2f2 [nucleoplasm] (Mus musculus)
    - Integrator complex processes the 3' end of snRNA (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2 [nucleoplasm] (Mus musculus)
        
        Pou2f2 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2 [nucleoplasm] (Mus musculus)
        
        Pou2f2 [nucleoplasm] (Mus musculus)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2 [nucleoplasm] (Mus musculus)
        
        Pou2f2 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2 [nucleoplasm] (Mus musculus)
        
        Pou2f2 [nucleoplasm] (Mus musculus)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Mus musculus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2 [nucleoplasm] (Mus musculus)
        
        Pou2f2 [nucleoplasm] (Mus musculus)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2 [nucleoplasm] (Mus musculus)
        
        Pou2f2 [nucleoplasm] (Mus musculus)
    - RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Mus musculus)
      - Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2 [nucleoplasm] (Mus musculus)
        
        Pou2f2 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2 [nucleoplasm] (Mus musculus)
        
        Pou2f2 [nucleoplasm] (Mus musculus)
    - RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Mus musculus)
      - RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2 [nucleoplasm] (Mus musculus)
        
        Pou2f2 [nucleoplasm] (Mus musculus)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        POU2F1,2 [nucleoplasm] (Mus musculus)
        
        Pou2f2 [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:Q00196

Gene Names

Pou2f2

Reference Genes

BioGPS Gene:18987 Pou2f2

ENSEMBL:ENSMUSG00000008496

KEGG:mmu:18987 Pou2f2

Monarch:18987 Pou2f2

NCBI Gene:18987 Pou2f2

UCSC:Q00196 Pou2f2

Reference Transcript

Other Identifiers

10560964

109527_at

1427713_x_at

1427725_a_at

1443885_at

17487855

18987

4346134

4394220

4422533

4443904

4458593

4465068

4468229

4596730

4636442

4641315

4643390

4647081

4755180

4817559

4869592

4905145

4986984

4997628

5025400

5068041

5068913

5073534

5107909

5184959

5190569

5220382

5316160

5359304

5397557

5443553

5510514

5532673

5538562

5584179

5602023

92305_s_at

A_51_P166728

A_51_P444795

A_55_P2057877

A_66_P121353

GE1398638

GE35923

GO:0000976

GO:0000978

GO:0000981

GO:0001228

GO:0002335

GO:0002376

GO:0003677

GO:0003700

GO:0005215

GO:0005634

GO:0005654

GO:0005737

GO:0006355

GO:0006357

GO:0015606

GO:0015848

GO:0019904

GO:0030154

GO:0032755

GO:0043226

GO:0043231

GO:0043565

GO:0045893

GO:0045944

GO:0048469

GO:0055085

GO:0098586

GO:0140110

GO:1903711

ILMN_2687602

mMC011511

x53654_s_at

Participates

as a member of

POU2F1,2 [nucleoplasm] (Mus musculus)

Inferred From

POU2F2 [nucleoplasm] (Homo sapiens)

Cross References

ENSEMBL

ENSMUSP00000104051, ENSMUSP00000096276, ENSMUSP00000135075, ENSMUSP00000104055, ENSMUSP00000104056, ENSMUSP00000104053, ENSMUSP00000104054, ENSMUST00000108413, ENSMUST00000108415, ENSMUST00000108416, ENSMUST00000098679, ENSMUST00000175774, ENSMUST00000108417, ENSMUST00000108418

PRO

Q00196

MGI

101897

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