Reactome | POU2F2 [nucleoplasm]

POU2F2 [nucleoplasm]

Stable Identifier

R-SSC-6814932

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

POU2F2, A0A5G2Q901

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Sus scrofa)

- RNA Polymerase II Transcription (Sus scrofa)
  - RNA polymerase II transcribes snRNA genes (Sus scrofa)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        POU2F1,2 [nucleoplasm] (Sus scrofa)
        
        POU2F2 [nucleoplasm] (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        POU2F1,2 [nucleoplasm] (Sus scrofa)
        
        POU2F2 [nucleoplasm] (Sus scrofa)
    - CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Sus scrofa)
      - RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        POU2F1,2 [nucleoplasm] (Sus scrofa)
        
        POU2F2 [nucleoplasm] (Sus scrofa)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        POU2F1,2 [nucleoplasm] (Sus scrofa)
        
        POU2F2 [nucleoplasm] (Sus scrofa)
    - Integrator complex processes the 3' end of snRNA (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        POU2F1,2 [nucleoplasm] (Sus scrofa)
        
        POU2F2 [nucleoplasm] (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        POU2F1,2 [nucleoplasm] (Sus scrofa)
        
        POU2F2 [nucleoplasm] (Sus scrofa)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        POU2F1,2 [nucleoplasm] (Sus scrofa)
        
        POU2F2 [nucleoplasm] (Sus scrofa)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        POU2F1,2 [nucleoplasm] (Sus scrofa)
        
        POU2F2 [nucleoplasm] (Sus scrofa)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Sus scrofa)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        POU2F1,2 [nucleoplasm] (Sus scrofa)
        
        POU2F2 [nucleoplasm] (Sus scrofa)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        POU2F1,2 [nucleoplasm] (Sus scrofa)
        
        POU2F2 [nucleoplasm] (Sus scrofa)
    - RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Sus scrofa)
      - Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        POU2F1,2 [nucleoplasm] (Sus scrofa)
        
        POU2F2 [nucleoplasm] (Sus scrofa)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        POU2F1,2 [nucleoplasm] (Sus scrofa)
        
        POU2F2 [nucleoplasm] (Sus scrofa)
    - RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Sus scrofa)
      - RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        POU2F1,2 [nucleoplasm] (Sus scrofa)
        
        POU2F2 [nucleoplasm] (Sus scrofa)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        POU2F1,2 [nucleoplasm] (Sus scrofa)
        
        POU2F2 [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A5G2Q901

Gene Names

POU2F2

Reference Genes

ENSEMBL:ENSSSCG00000037132.3

UCSC:A0A5G2Q901 POU2F2

Other Identifiers

397105

GO:0000976

GO:0000978

GO:0000981

GO:0001228

GO:0002335

GO:0002376

GO:0003677

GO:0003700

GO:0005634

GO:0005654

GO:0006355

GO:0006357

GO:0015606

GO:0015848

GO:0019904

GO:0030154

GO:0032755

GO:0043565

GO:0045893

GO:0045944

GO:0048469

GO:0055085

GO:0098586

GO:1903711

Ssc.145.1.S1_at

Participates

as a member of

POU2F1,2 [nucleoplasm] (Sus scrofa)

Inferred From

POU2F2 [nucleoplasm] (Homo sapiens)

Cross References

ENSEMBL

ENSSSCG00000037132, ENSSSCT00000083405, ENSSSCP00000060397

VGNC

91673

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