After phosphorylation by MAP2Ks, the scaffolded kinase complex assembled by oncogenic RAS presumably dissociates, as is the case for WT complexes (reviewed in Lavoie and Therrien et al, 2015; Stephen et al, 2014).
Stephen, AG, Esposito, D, Bagni, RK, McCormick, F
Lavoie, H, Therrien, M
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