AKAP9(1-1118)-p-BRAF(381-766) fusion [cytosol]

Stable Identifier
R-HSA-6802514
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
15630448 Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer

Ciampi, R, Knauf, JA, Kerler, R, Gandhi, M, Zhu, Z, Nikiforova, MN, Rabes, HM, Fagin, JA, Nikiforov, YE

J. Clin. Invest. 2005
External Reference Information
External Reference
UniProt:Q99996 AKAP9
Gene Names
AKAP9, AKAP350, AKAP450, KIAA0803
Chain
chain:1-3907
Reference Genes
BioGPS Gene:10142 AKAP9
COSMIC (genes):AKAP9 AKAP9
CTD Gene:10142 AKAP9
dbSNP Gene:10142 AKAP9
ENSEMBL:ENSG00000127914 AKAP9
HGNC:379 AKAP9
KEGG:hsa:10142 AKAP9
Monarch:10142 AKAP9
NCBI Gene:10142 AKAP9
OMIM:604001 AKAP9
UCSC:Q99996 AKAP9
Reference Transcript
Participates
as a component of
Other forms of this molecule
AKAP9(1-1118)-BRAF(381-766) fusion [cytosol]
AKAP9 [cytosol]
Modified Residues
Name
Insertion of residues 381 to 766 at 1119 from UniProt:P15056 BRAF
Coordinate
1119
Name
O-phospho-L-serine at 446
Coordinate
446
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 729
Coordinate
729
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 599
Coordinate
599
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 602
Coordinate
602
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Disease
Name Identifier Synonyms
thyroid cancer DOID:1781 Thyroid gland neoplasm, thyroid cancer, thyroid neoplasm, neoplasm of thyroid gland, thyroid neoplasm, Thyroid neoplasm, malignant tumour of thyroid gland, malignant neoplasm of thyroid gland
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Cross References
RefSeq
ENSEMBL
OpenTargets
Mondo
GeneCards
HPA
PRO
Pharos - Targets
GlyGen
Orphanet
HMDB Protein
Interactors (4)
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