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ELANE [specific granule lumen]
Stable Identifier
R-HSA-6800918
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
specific granule lumen
Synonyms
Neutrophil elastase, ELA2, ELNE_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of specific granule lumen proteins (Homo sapiens)
Specific granule lumen proteins [specific granule lumen] (Homo sapiens)
ELANE [specific granule lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P08246 ELANE
Gene Names
ELANE, ELA2
Chain
signal peptide:1-27, propeptide:28-29, chain:30-267
Reference Genes
BioGPS Gene:1991 ELANE
COSMIC (genes):ELANE ELANE
CTD Gene:1991 ELANE
dbSNP Gene:1991 ELANE
ENSEMBL:ENSG00000197561 ELANE
HGNC:3309 ELANE
KEGG:hsa:1991 ELANE
Monarch:1991 ELANE
NCBI Gene:1991 ELANE
OMIM:130130 ELANE
UCSC:P08246 ELANE
Reference Transcript
RefSeq:XM_011527776.1 ELANE
RefSeq:XM_011527775.1 ELANE
RefSeq:NM_001972.3 ELANE
Other Identifiers
11727965_at
16856292
1991
206871_PM_at
206871_at
37096_at
3815234
3815235
3815236
3815237
3815238
3815239
3815240
3815241
3815242
8024056
A_14_P112290
A_23_P130961
GO:0000122
GO:0001878
GO:0002020
GO:0002376
GO:0002438
GO:0002523
GO:0002812
GO:0003714
GO:0003824
GO:0004175
GO:0004252
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005829
GO:0006355
GO:0006508
GO:0006874
GO:0006909
GO:0006954
GO:0008201
GO:0008233
GO:0008236
GO:0009411
GO:0009986
GO:0012501
GO:0016192
GO:0016787
GO:0017053
GO:0019955
GO:0022617
GO:0030141
GO:0030163
GO:0030198
GO:0030312
GO:0031012
GO:0031410
GO:0032496
GO:0032682
GO:0032717
GO:0032757
GO:0035578
GO:0035580
GO:0042742
GO:0043226
GO:0043406
GO:0045335
GO:0048661
GO:0048870
GO:0050728
GO:0050778
GO:0050832
GO:0050900
GO:0050922
GO:0060090
GO:0062023
GO:0070062
GO:0070269
GO:0070945
GO:0070947
GO:0098542
GO:0140096
GO:0140110
GO:1903238
HMNXSV003020870
ILMN_1706635
M20203_s_at
M27783_s_at
PH_hs_0005576
TC19000019.hg
Y00477_at
g4503548_3p_at
Participates
as a member of
Specific granule lumen proteins [specific granule lumen] (Homo sapiens)
Other forms of this molecule
ELANE [extracellular region]
ELANE [cytosol]
ELANE [azurophil granule lumen]
Inferred To
Elane [specific granule lumen]
(Mus musculus)
Elane [specific granule lumen]
(Rattus norvegicus)
prtn3 [specific granule lumen]
(Xenopus tropicalis)
ELANE [specific granule lumen]
(Bos taurus)
ELANE [specific granule lumen]
(Sus scrofa)
ELA2 [specific granule lumen]
(Canis familiaris)
Cross References
RefSeq
NP_001963.1
,
XP_011526077.1
,
XP_011526078.1
ZINC - World Drugs
ELNE_HUMAN
Guide to Pharmacology - Targets
2358
OpenTargets
ENSG00000197561
ENSEMBL
ENSP00000466090
,
ENST00000590230
,
ENSP00000480128
,
ENST00000615489
,
ENST00000632488
,
ENST00000263621
,
ENSP00000488075
,
ENSP00000263621
ZINC - FDA approved
ELNE_HUMAN
ZINC - Substances
ELNE_HUMAN
ZINC - Biogenic
ELNE_HUMAN
ZINC target
P08246
PRO
P08246
PDB
6F5M
,
8D7K
,
5A09
,
1B0F
,
8D7I
,
7CBK
,
5ABW
,
5A0A
,
4NZL
,
7WHU
,
5A0C
,
5A0B
,
5A8Z
,
8G25
,
8G24
,
8G26
,
5A8X
,
5A8Y
,
6E69
,
8D4Q
,
6SMA
,
1H1B
,
8D4U
,
1PPF
,
1PPG
,
1HNE
,
2RG3
,
2Z7F
,
4WVP
,
3Q76
,
3Q77
ZINC - Investigational
ELNE_HUMAN
IntEnz
3.4.21.37
HPA
ENSG00000197561-ELANE
Pharos - Targets
P08246
Orphanet
ELANE
ZINC - Predictions - Purchasable
ELNE_HUMAN
HMDB Protein
HMDBP13378
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