PIDD1 phosphorylated by ATM at threonine residue T788 associates with CRADD (RAIDD), forming a multisubunit structure known as the PIDDosome (Tinel and Tschopp 2004, Ando et al. 2012). The PIDDosome consists of 5 molecules of PIDD1 and 5-7 molecules of CRADD (Nematollahi et al. 2015).
Tinel, A, Tschopp, J
Morgner, N, Nematollahi, LA, Garza-Garcia, A, Robinson, CV, Driscoll, PC, Bechara, C, Esposito, D
Sanda, T, Liu, PH, Wang, J, Look, AT, Logette, E, Bouchier-Hayes, L, Kernan, JL, Tschopp, J, Ando, K, Sidi, S
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