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MST1R (25-304) [plasma membrane]
Stable Identifier
R-HSA-6800303
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Macrophage-stimulating protein receptor, RON_HUMAN, MST1R alpha chain
Icon
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by MST1 (Homo sapiens)
MST1 binds MST1R (Homo sapiens)
MST1 dimer:MST1R dimer [plasma membrane] (Homo sapiens)
MST1R dimer [plasma membrane] (Homo sapiens)
MST1R (25-304) [plasma membrane] (Homo sapiens)
MST1R dimer [plasma membrane] (Homo sapiens)
MST1R (25-304) [plasma membrane] (Homo sapiens)
MST1 dimer:MST1R dimer binds MST1R dimer (Homo sapiens)
MST1 dimer:2xMST1R dimer [plasma membrane] (Homo sapiens)
MST1 dimer:MST1R dimer [plasma membrane] (Homo sapiens)
MST1R dimer [plasma membrane] (Homo sapiens)
MST1R (25-304) [plasma membrane] (Homo sapiens)
MST1R dimer [plasma membrane] (Homo sapiens)
MST1R (25-304) [plasma membrane] (Homo sapiens)
MST1 dimer:MST1R dimer [plasma membrane] (Homo sapiens)
MST1R dimer [plasma membrane] (Homo sapiens)
MST1R (25-304) [plasma membrane] (Homo sapiens)
MST1R dimer [plasma membrane] (Homo sapiens)
MST1R (25-304) [plasma membrane] (Homo sapiens)
MST1R autophosphorylates (Homo sapiens)
MST1 dimer:2x p-4Y-MST1R dimer [plasma membrane] (Homo sapiens)
p-4Y-MST1R dimer [plasma membrane] (Homo sapiens)
MST1R (25-304) [plasma membrane] (Homo sapiens)
MST1 dimer:2xMST1R dimer [plasma membrane] (Homo sapiens)
MST1 dimer:MST1R dimer [plasma membrane] (Homo sapiens)
MST1R dimer [plasma membrane] (Homo sapiens)
MST1R (25-304) [plasma membrane] (Homo sapiens)
MST1R dimer [plasma membrane] (Homo sapiens)
MST1R (25-304) [plasma membrane] (Homo sapiens)
p-4Y-MST1R dimer [plasma membrane] (Homo sapiens)
MST1R (25-304) [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q04912 MST1R
Gene Names
MST1R, PTK8, RON
Chain
signal peptide:1-24, chain:25-1400, chain:25-304, chain:310-1400
Reference Genes
BioGPS Gene:4486 MST1R
COSMIC (genes):MST1R MST1R
CTD Gene:4486 MST1R
dbSNP Gene:4486 MST1R
ENSEMBL:ENSG00000164078 MST1R
HGNC:7381 MST1R
Monarch:4486 MST1R
NCBI Gene:4486 MST1R
OMIM:600168 MST1R
UCSC:Q04912 MST1R
Reference Transcript
RefSeq:NM_002447.3 MST1R
RefSeq:NM_001244937.2 MST1R
Other Identifiers
11725019_a_at
11749262_a_at
11749743_a_at
11752174_a_at
1317_at
16954295
205455_PM_at
205455_at
2674923
2674924
2674925
2674926
2674927
2674928
2674929
2674930
2674931
2674932
2674933
2674934
2674935
2674937
2674938
2674939
2674940
2674941
2674942
2674943
2674944
2674945
2674946
2674947
2674948
2674949
2674950
2674951
2674952
2674953
2674954
2674955
2674956
2674957
2674958
2674959
2674960
4486
8087547
A_23_P256312
GE81156
GO:0001725
GO:0002376
GO:0003824
GO:0004672
GO:0004713
GO:0004714
GO:0005011
GO:0005515
GO:0005524
GO:0005773
GO:0005886
GO:0006468
GO:0006909
GO:0006952
GO:0007165
GO:0007169
GO:0007338
GO:0007399
GO:0008284
GO:0009615
GO:0009986
GO:0016020
GO:0016192
GO:0016477
GO:0016740
GO:0017154
GO:0019899
GO:0022414
GO:0038145
GO:0043226
GO:0043235
GO:0043406
GO:0045087
GO:0048856
GO:0048870
GO:0051897
GO:0060089
GO:0071526
GO:0098542
GO:0140096
HMNXSV003001375
HMNXSV003021167
ILMN_1688154
PH_hs_0000373
TC03001421.hg
X70040_at
g4505264_3p_at
g4505264_3p_x_at
Participates
as a component of
p-4Y-MST1R dimer [plasma membrane] (Homo sapiens)
MST1R dimer [plasma membrane] (Homo sapiens)
Other forms of this molecule
p-Y1238,1239,1353,1360-MST1R (310-1400) [plasma membrane]
MST1R (310-1400) [plasma membrane]
Inferred To
MST1R (25-304) [plasma membrane]
(Bos taurus)
MST1R (25-304) [plasma membrane]
(Caenorhabditis elegans)
MST1R (25-304) [plasma membrane]
(Canis familiaris)
MST1R (25-304) [plasma membrane]
(Danio rerio)
MST1R (25-304) [plasma membrane]
(Gallus gallus)
MST1R (25-304) [plasma membrane]
(Mus musculus)
MST1R (25-304) [plasma membrane]
(Rattus norvegicus)
MST1R (25-304) [plasma membrane]
(Sus scrofa)
MST1R (25-304) [plasma membrane]
(Xenopus tropicalis)
Homologues of MST1R (25-304) [plasma membrane]
(Caenorhabditis elegans)
Cross References
ZINC - World Drugs
RON_HUMAN
Guide to Pharmacology - Targets
1816
ENSEMBL
ENSP00000341325
,
ENSP00000482642
,
ENST00000296474
,
ENST00000344206
,
ENSP00000296474
,
ENST00000621387
OpenTargets
ENSG00000164078
ZINC - FDA approved
RON_HUMAN
ZINC - Substances
RON_HUMAN
ZINC - Biogenic
RON_HUMAN
ZINC target
Q04912
PRO
Q04912
GlyGen
Q04912
PDB
4FWW
,
4QT8
,
3PLS
ZINC - Investigational
RON_HUMAN
HPA
ENSG00000164078-MST1R
Pharos - Targets
Q04912
ZINC - Predictions - Purchasable
RON_HUMAN
HMDB Protein
HMDBP01157
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P26927 MST1
3
MST1(19-483) [extracellular region]
(R-HSA-6800207)
MST1(484-711) [extracellular region]
(R-HSA-6800230)
pro-MST1 [extracellular region]
(R-HSA-6800227)
0.715
5
UniProt:Q9ULL4 PLXNB3
1
PLXNB3 [plasma membrane]
(R-HSA-416675)
0.524
2
UniProt:O43157 PLXNB1
2
p-Y-PLXNB1 [plasma membrane]
(R-HSA-419609)
PLXNB1 [plasma membrane]
(R-HSA-3008951)
0.524
3
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