Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
pro-MST1 [extracellular region]
Stable Identifier
R-HSA-6800227
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
MST1(19-711), Hepatocyte growth factor-like protein, HGFL_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by MST1 (Homo sapiens)
HPN heterodimer cleaves pro-MST1 to form MST1 dimer (Homo sapiens)
pro-MST1 [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P26927 MST1
Gene Names
MST1, D3F15S2, DNF15S2, HGFL
Chain
signal peptide:1-18, chain:19-711, chain:19-483, chain:484-711
Reference Genes
BioGPS Gene:4485 MST1
COSMIC (genes):MST1 MST1
CTD Gene:4485 MST1
dbSNP Gene:4485 MST1
ENSEMBL:ENSG00000173531 MST1
HGNC:7380 MST1
KEGG Gene (Homo sapiens):4485 MST1
Monarch:4485 MST1
NCBI Gene:4485 MST1
OMIM:142408 MST1
Reference Transcript
RefSeq:NM_020998.3 MST1
Participates
as an input of
HPN heterodimer cleaves pro-MST1 to form MST1 dimer (Homo sapiens)
Other forms of this molecule
MST1(19-483) [extracellular region]
MST1(484-711) [extracellular region]
Inferred To
MST1 [extracellular region]
(Bos taurus)
MST1 [extracellular region]
(Canis familiaris)
MST1 [extracellular region]
(Sus scrofa)
pro-MST1 [extracellular region]
(Caenorhabditis elegans)
pro-MST1 [extracellular region]
(Gallus gallus)
Mst1 [extracellular region]
(Mus musculus)
Mst1 [extracellular region]
(Rattus norvegicus)
mst1 [extracellular region]
(Danio rerio)
mst1 [extracellular region]
(Xenopus tropicalis)
Cross References
RefSeq
NP_066278.3
OpenTargets
ENSG00000173531
GeneCards
P26927
PRO
P26927
Pharos - Targets
P26927
Orphanet
22414
PDB
2ASU
,
4QT8
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q04912 MST1R
3
p-Y1238,1239,1353,1360-MST1R (310-1400) [plasma membrane]
(R-HSA-8852533)
MST1R (310-1400) [plasma membrane]
(R-HSA-6800308)
MST1R (25-304) [plasma membrane]
(R-HSA-6800303)
0.715
5
UniProt:Q8WV19 SFT2A
0.556
3
UniProt:Q15831 STK11
2
STK11 [cytosol]
(R-HSA-380954)
STK11 [nucleoplasm]
(R-HSA-164119)
0.499
2
UniProt:Q99IB8-PRO_0000045599
0.488
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text