Reactome | CRACR2A [specific granule lumen]

CRACR2A [specific granule lumen]

Stable Identifier

R-HSA-6799553

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

specific granule lumen

Synonyms

EFCAB4B, EF-hand calcium-binding domain-containing protein 4B, EFC4B_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9BSW2 CRACR2A

Gene Names

CRACR2A, EFCAB4B, RAB46

Chain

chain:1-731

Reference Genes

BioGPS Gene:84766 CRACR2A

COSMIC (genes):CRACR2A CRACR2A

CTD Gene:84766 CRACR2A

dbSNP Gene:84766 CRACR2A

ENSEMBL:ENSG00000130038 CRACR2A

HGNC:28657 CRACR2A

KEGG:hsa:84766 CRACR2A

Monarch:84766 CRACR2A

NCBI Gene:84766 CRACR2A

OMIM:614178 CRACR2A

UCSC:Q9BSW2 CRACR2A

Reference Transcript

Other Identifiers

11737647_at

11738024_a_at

11741982_a_at

1560874_PM_at

1560874_at

16760082

223955_PM_at

223955_at

228752_PM_at

228752_at

3440925

3440926

3440927

3440932

3440933

3440934

3440935

3440936

3440938

3440940

3440941

3440942

3440945

3440946

3440949

3440951

3440952

3440953

3440954

3440955

3440956

3440959

3440960

3440963

3440968

3440970

3440972

3440978

3440979

3440980

3440982

3440987

3440988

3440989

3440990

3440991

3440994

3440997

70391_at

7960365

7960370

7960381

84766

88564_at

A_23_P128351

A_32_P462013

A_33_P3314151

GE83479

GO:0000139

GO:0001772

GO:0002115

GO:0002250

GO:0002376

GO:0003824

GO:0003924

GO:0005509

GO:0005515

GO:0005525

GO:0005576

GO:0005737

GO:0005794

GO:0005815

GO:0005856

GO:0005886

GO:0006816

GO:0008104

GO:0016020

GO:0016192

GO:0016197

GO:0016787

GO:0030154

GO:0031410

GO:0031982

GO:0032237

GO:0032588

GO:0033093

GO:0034776

GO:0035580

GO:0043226

GO:0045063

GO:0046330

GO:0046872

GO:0051928

HMNXSV003008410

HMNXSV003038916

HMNXSV003048487

HMNXSV003052992

Hs.288512.0.S1_3p_at

Hs2.209392.1.A1_3p_at

ILMN_1693293

ILMN_1796436

PH_hs_0023508

PH_hs_0035755

TC12001115.hg

g13477100_3p_at

Participates

as a member of

Specific granule lumen proteins [specific granule lumen] (Homo sapiens)

Other forms of this molecule

CRACR2A [extracellular region]

Inferred To

Homologues of CRACR2A [specific granule lumen] (Dictyostelium discoideum)

Cracr2a [specific granule lumen] (Rattus norvegicus)

CRACR2A [specific granule lumen] (Bos taurus)

CRACR2A [specific granule lumen] (Caenorhabditis elegans)

CRACR2A [specific granule lumen] (Canis familiaris)

CRACR2A [specific granule lumen] (Dictyostelium discoideum)

CRACR2A [specific granule lumen] (Mus musculus)

CRACR2A [specific granule lumen] (Sus scrofa)

Cross References

ENSEMBL

ENSP00000409382, ENSP00000252322, ENST00000440314, ENST00000252322

OpenTargets

ENSG00000130038

HPA

ENSG00000130038-CRACR2A

PRO

Q9BSW2

Pharos - Targets

Q9BSW2

GlyGen

Q9BSW2

PDB

6PSD

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q08117 TLE5	1	AES [nucleoplasm] (R-HSA-4648963)	0.666	4
UniProt:Q96AJ1 CLUAP1	2	CLUAP [ciliary tip] (R-HSA-5637957) CLUAP [cilium] (R-HSA-5637960)	0.589	2
UniProt:P09022 Hoxa1	1	Hoxa1 [nucleoplasm] (R-MMU-5617924)	0.57	3
UniProt:Q8NEM0 MCPH1	1	MCPH1 [nucleoplasm] (R-HSA-2429638)	0.564	2
UniProt:Q7Z3S9 NOTCH2NLA	3	NOTCH2NLA [extracellular region] (R-HSA-9908935) NOTCH2NLA(1-?) [extracellular region] (R-HSA-9911493) NOTCH2NLA(?-236) [extracellular region] (R-HSA-9911490)	0.556	3
UniProt:O15160 POLR1C	2	POLR1C [cytosol] (R-HSA-1964454) POLR1C [nucleoplasm] (R-HSA-63498)	0.556	3
UniProt:Q13077 TRAF1	3	TRAF1 [cytosol] (R-HSA-5634163) TRAF1(1-163) [cytosol] (R-HSA-5634199) TRAF1(164-416) [cytosol] (R-HSA-5634204)	0.556	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	9
UniProt:O75344 FKBP6	2	FKBP6 [nucleoplasm] (R-HSA-912512) FKBP6 [cytosol] (R-HSA-5601923)	0.556	3
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.556	3
UniProt:O75604 USP2	2	USP2 [cytosol] (R-HSA-5212661) USP2 [nucleoplasm] (R-HSA-5689946)	0.556	3
UniProt:P35638 DDIT3	1	DDIT3 [nucleoplasm] (R-HSA-381110)	0.556	3