Reactome | FKBP6 [nucleoplasm]

FKBP6 [nucleoplasm]

Stable Identifier

R-HSA-912512

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Peptidyl-prolyl cis-trans isomerase FKBP6, FKBP6_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O75344 FKBP6

Gene Names

FKBP6, FKBP36

Chain

chain:1-327

Reference Genes

BioGPS Gene:8468 FKBP6

COSMIC (genes):FKBP6 FKBP6

CTD Gene:8468 FKBP6

dbSNP Gene:8468 FKBP6

ENSEMBL:ENSG00000077800 FKBP6

ENSEMBL_homo_sapiens_GENE:ENSG00000077800.13 FKBP6

HGNC:3722 FKBP6

KEGG Gene (Homo sapiens):8468 FKBP6

Monarch:8468 FKBP6

NCBI Gene:8468 FKBP6

OMIM:604839 FKBP6

UCSC:O75344 FKBP6

Reference Transcript

Other Identifiers

11725605_a_at

17046920

206763_PM_at

206763_at

3007579

3007580

3007581

3007584

3007593

3007594

3007595

3007596

3007597

3007598

3007599

3007600

3007601

3007602

3007603

3007604

3007605

3057159

3057162

3057163

3057164

3057165

38137_at

8133293

84525_at

8468

A_14_P115792

A_23_P250874

GE54329

GO:0000228

GO:0000795

GO:0003755

GO:0003824

GO:0005515

GO:0005528

GO:0005634

GO:0005694

GO:0005737

GO:0005829

GO:0006457

GO:0007283

GO:0016853

GO:0022414

GO:0030154

GO:0031047

GO:0034587

GO:0042802

GO:0043226

GO:0045070

GO:0051321

GO:0051879

GO:0140096

GO:0141007

HMNXSV003005410

ILMN_1815444

PH_hs_0009061

TC07002396.hg

TC07003330.hg

g4503730_3p_at

Participates

as a component of

Synaptonemal Complex [nucleoplasm] (Homo sapiens)

as an input of

Synapsis (Homo sapiens)

Other forms of this molecule

FKBP6 [cytosol]

Cross References

RefSeq

NP_001128683.1, NP_001268233.1, NP_003593.3

OpenTargets

ENSG00000077800

GeneCards

O75344

HPA

ENSG00000077800-FKBP6

Ensembl

ENSG00000077800, ENSP00000394952, ENSP00000416277, ENST00000431982, ENST00000252037, ENST00000413573, ENSP00000252037

PRO

O75344

Pharos - Targets

O75344

PDB

3B7X

Interactors (48)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96JB5 CK5P3			0.857	12
UniProt:Q8IYA8 IHO1			0.83	8
UniProt:Q9BRK4 LZTS2			0.781	7
UniProt:G2XKQ0 SUMO5			0.718	6
UniProt:P22059 OSBP	1	OSBP [cytosol] (R-HSA-429725)	0.708	5
UniProt:O75344 FKBP6	2	FKBP6 [nucleoplasm] (R-HSA-912512) FKBP6 [cytosol] (R-HSA-5601923)	0.675	7
UniProt:Q9Y5B8 NME7	1	NME7 [cytosol] (R-HSA-6806880)	0.666	4
UniProt:Q9WMX2-PRO_0000037551			0.602	6
UniProt:P27918 CFP	6	CFP [extracellular region] (R-HSA-173751) CFP [specific granule lumen] (R-HSA-6799522) CFP [tertiary granule lumen] (R-HSA-6800993) O-fuc-CFP [endoplasmic reticulum lumen] (R-HSA-5173204) glc-fuc-CFP [endoplasmic reticulum lumen] (R-HSA-5173137) CFP [endoplasmic reticulum lumen] (R-HSA-5173244)	0.601	4
UniProt:Q7L804 RAB11FIP2	1	RAB11FIP2 [cytoplasmic vesicle membrane] (R-HSA-2028707)	0.556	3
UniProt:Q9BSW2 CRACR2A	2	CRACR2A [extracellular region] (R-HSA-6806289) CRACR2A [specific granule lumen] (R-HSA-6799553)	0.556	3
UniProt:P35520 CBS	1	PXLP-K119-CBS [cytosol] (R-HSA-1614563)	0.556	3
UniProt:Q96D03 DDT4L			0.556	3
UniProt:A8MW99 MEI4			0.556	3
UniProt:P29692-2 EEF1D			0.556	3
UniProt:Q9Y2H0-1 DLGAP4			0.556	3
UniProt:Q7Z5V6-2 SAXO4			0.556	6
UniProt:P23560-2 BDNF			0.556	3
UniProt:Q63ZY3 KANK2			0.556	3
UniProt:Q9H0I2 ENKD1			0.556	3
UniProt:Q6FHY5 Q6FHY5			0.556	3
UniProt:O95678 KRT75	1	KRT75 [cytosol] (R-HSA-6809652)	0.556	3
UniProt:Q96N21 AP4AT			0.556	3
UniProt:E9PSE9 E9PSE9			0.556	3
UniProt:P04406 GAPDH	1	GAPDH [cytosol] (R-HSA-70428)	0.556	3
UniProt:O15499 GSC2			0.556	3
UniProt:P50222 MEOX2			0.556	3
UniProt:P78317 RNF4	2	RNF4 [nucleoplasm] (R-HSA-5684076) RNF4 [cytosol] (R-HSA-975974)	0.556	3
UniProt:Q9NQ34 TMM9B			0.556	3
UniProt:Q8N720 ZNF655	1	ZNF655 [nucleoplasm] (R-HSA-2127575)	0.556	3
UniProt:Q96HA8 NTAQ1			0.556	3
IntAct:EBI-25847655 CCSB			0.556	3
UniProt:Q16610 ECM1	2	ECM1 [extracellular region] (R-HSA-8848909) ECM1 [platelet dense granule lumen] (R-HSA-8848880)	0.556	3
UniProt:Q9UNE7 STUB1	1	STUB1 [cytosol] (R-HSA-975970)	0.556	3
UniProt:Q9NRD5 PICK1	2	PICK1 [endocytic vesicle membrane] (R-HSA-417017) PICK1 [plasma membrane] (R-HSA-416989)	0.556	3
UniProt:O75928-2 PIAS2	1	PIAS2-2 [nucleoplasm] (R-HSA-2993779)	0.556	5
UniProt:P30838 ALDH3A1	1	ALDH3A1 [cytosol] (R-HSA-5692291)	0.556	3
UniProt:Q9BPY3 F118B			0.527	2
UniProt:O60237 PPP1R12B	1	PPP1R12B [cytosol] (R-HSA-419178)	0.527	2
UniProt:Q58FG0 HS905			0.527	2
UniProt:Q9H6R7 WDCP	2	WDCP(1-680)-p-7Y-ALK(1061-1620) fusion [cytosol] (R-HSA-9700468) WDCP(1-680)-ALK(1061-1620) fusion [cytosol] (R-HSA-9700460)	0.527	2
UniProt:Q7Z6J8 UBE3D	1	UBE3D [cytosol] (R-HSA-8851647)	0.527	2
UniProt:Q7L3B6 CDC37L1	2	CDC37L1 [extracellular region] (R-HSA-8848918) CDC37L1 [platelet dense granule lumen] (R-HSA-8848903)	0.527	3
UniProt:P27815 PDE4A	1	PDE4A [cytosol] (R-HSA-52383)	0.527	3
UniProt:O94966 USP19	1	USP19 [cytosol] (R-HSA-6781794)	0.527	3
UniProt:Q9BZK7 TBL1XR1	1	TBL1XR1 [nucleoplasm] (R-HSA-351643)	0.527	2
UniProt:Q13123 IK	1	IK [nucleoplasm] (R-HSA-9770239)	0.527	2
UniProt:O00418 EEF2K	2	p-S366-EEF2K [cytosol] (R-HSA-165755) EEF2K [cytosol] (R-HSA-165745)	0.527	2

Cite Us!