Reactome | LPCAT1 [azurophil granule membrane]

LPCAT1 [azurophil granule membrane]

Stable Identifier

R-HSA-6798758

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

azurophil granule membrane

Synonyms

Lysophosphatidylcholine acyltransferase 1, PFAAP3

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8NF37 LPCAT1

Gene Names

LPCAT1, AYTL2, PFAAP3

Chain

chain:1-534

Reference Genes

BioGPS Gene:79888 LPCAT1

COSMIC (genes):LPCAT1 LPCAT1

CTD Gene:79888 LPCAT1

dbSNP Gene:79888 LPCAT1

ENSEMBL:ENSG00000153395 LPCAT1

HGNC:25718 LPCAT1

KEGG:hsa:79888 LPCAT1

Monarch:79888 LPCAT1

NCBI Gene:79888 LPCAT1

OMIM:610472 LPCAT1

UCSC:Q8NF37 LPCAT1

Reference Transcript

RefSeq:NM_024830.4 LPCAT1

Other Identifiers

11715638_s_at

16994002

201818_PM_at

201818_at

2845975

2845976

2845977

2845978

2845979

2845980

2845981

2845982

2845983

2845985

2845986

2845987

2845989

2845990

2845992

2845993

2845996

2845997

2846003

2846004

2846005

2846009

2846010

2846011

2846026

2846029

2846030

2846031

2846032

2846033

2846034

41176_at

41177_at

79888

8110841

A_23_P213471

A_24_P406006

GE54472

GO:0000139

GO:0003824

GO:0003841

GO:0005509

GO:0005783

GO:0005789

GO:0005794

GO:0005811

GO:0005886

GO:0006629

GO:0006644

GO:0006654

GO:0006656

GO:0008374

GO:0008654

GO:0016020

GO:0016740

GO:0016746

GO:0030163

GO:0035577

GO:0036148

GO:0036151

GO:0042171

GO:0043129

GO:0043226

GO:0045732

GO:0046872

GO:0047144

GO:0047159

GO:0047184

GO:0047191

GO:0047192

GO:0048856

GO:0060041

GO:2001246

HMNXSV003047580

ILMN_1702171

PH_hs_0010652

PH_hs_0039651

TC05001110.hg

g13376233_3p_at

Participates

as a member of

Azurophil granule membrane proteins [azurophil granule membrane] (Homo sapiens)

Other forms of this molecule

LPCAT1 [plasma membrane]

LPCAT1 [endoplasmic reticulum membrane]

Inferred To

lpcat1 [azurophil granule membrane] (Danio rerio)

lpcat1 [azurophil granule membrane] (Xenopus tropicalis)

LPCAT [azurophil granule membrane] (Drosophila melanogaster)

LPCAT1 [azurophil granule membrane] (Bos taurus)

LPCAT1 [azurophil granule membrane] (Canis familiaris)

LPCAT1 [azurophil granule membrane] (Gallus gallus)

LPCAT1 [azurophil granule membrane] (Mus musculus)

LPCAT1 [azurophil granule membrane] (Plasmodium falciparum)

LPCAT1 [azurophil granule membrane] (Rattus norvegicus)

LPCAT1 [azurophil granule membrane] (Sus scrofa)

Cross References

RefSeq

NP_079106.3

ENSEMBL

ENSG00000153395, ENST00000283415, ENSP00000283415, ENST00000475622, ENSP00000423472

OpenTargets

ENSG00000153395

GeneCards

LPCAT1

HPA

ENSG00000153395-LPCAT1

PRO

Q8NF37

Pharos - Targets

Q8NF37

GlyGen

Q8NF37

HMDB Protein

HMDBP07289

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13418 ILK	1	ILK [cytosol] (R-HSA-432864)	0.527	2
UniProt:O14975 SLC27A2	5	SLC27A2 [cytosol] (R-HSA-9033090) SLC27A2 [endoplasmic reticulum membrane] (R-HSA-193386) SLC27A2 [plasma membrane] (R-HSA-6806316) SLC27A2 [specific granule membrane] (R-HSA-6799565) SLC27A2 [peroxisomal membrane] (R-HSA-389579)	0.527	3
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	9

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