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TBL3 [nucleoplasm]
Stable Identifier
R-HSA-6790620
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Transducin beta-like protein 3, TBL3_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
rRNA processing (Homo sapiens)
rRNA processing in the nucleus and cytosol (Homo sapiens)
Major pathway of rRNA processing in the nucleolus and cytosol (Homo sapiens)
21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA (Homo sapiens)
18SE pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
UTPB complex [nucleoplasm] (Homo sapiens)
TBL3 [nucleoplasm] (Homo sapiens)
21S pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
UTPB complex [nucleoplasm] (Homo sapiens)
TBL3 [nucleoplasm] (Homo sapiens)
30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA (Homo sapiens)
21S pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
UTPB complex [nucleoplasm] (Homo sapiens)
TBL3 [nucleoplasm] (Homo sapiens)
30S pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
UTPB complex [nucleoplasm] (Homo sapiens)
TBL3 [nucleoplasm] (Homo sapiens)
45S pre-rRNA is nucleolytically processed at site 2 (site 2b) to yield 30S pre-rRNA and 32S pre-rRNA (Homo sapiens)
30S pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
UTPB complex [nucleoplasm] (Homo sapiens)
TBL3 [nucleoplasm] (Homo sapiens)
45S pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
UTPB complex [nucleoplasm] (Homo sapiens)
TBL3 [nucleoplasm] (Homo sapiens)
47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA (Homo sapiens)
45S pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
UTPB complex [nucleoplasm] (Homo sapiens)
TBL3 [nucleoplasm] (Homo sapiens)
47S pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
UTPB complex [nucleoplasm] (Homo sapiens)
TBL3 [nucleoplasm] (Homo sapiens)
rRNA modification in the nucleus and cytosol (Homo sapiens)
EMG1 of the SSU processome methylates pseudouridine-1248 of 18S rRNA yielding N(1)-methylpseudouridine-1248 (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
UTPB complex [nucleoplasm] (Homo sapiens)
TBL3 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q12788 TBL3
Gene Names
TBL3, SAZD
Chain
initiator methionine:, chain:2-808
Reference Genes
BioGPS Gene:10607 TBL3
COSMIC (genes):TBL3 TBL3
CTD Gene:10607 TBL3
dbSNP Gene:10607 TBL3
ENSEMBL:ENSG00000183751 TBL3
ENSEMBL_homo_sapiens_GENE:ENSG00000183751.16 TBL3
ENSEMBL_homo_sapiens_GENE:ENSG00000291938.1 TBL3
HGNC:11587 TBL3
KEGG Gene (Homo sapiens):10607 TBL3
Monarch:10607 TBL3
NCBI Gene:10607 TBL3
OMIM:605915 TBL3
UCSC:Q12788 TBL3
Reference Transcript
RefSeq:NM_006453.2 TBL3
Other Identifiers
10607
11722026_a_at
11723766_at
1564683_PM_at
1564683_at
16814872
16814895
204659_PM_s_at
204659_s_at
209820_PM_s_at
209820_s_at
3644250
3644251
3644252
3644254
3644255
3644256
3644257
3644258
3644260
3644261
3644262
3644264
3644265
3644267
3644269
3644271
3644272
3644274
3644275
3644276
3644278
3644280
3644281
3644282
3644283
3644285
3644286
3644287
3644288
3644290
3644292
3644294
3644296
3644298
3644299
3644300
3644301
3644302
3644303
3644304
3644305
3644306
3644307
41603_at
7992414
7992439
A_14_P100865
A_14_P105686
A_23_P106720
A_23_P206484
A_24_P31003
A_32_P439561
A_33_P3375398
A_33_P3577120
GE58854
GE59073
GE807261
GO:0000472
GO:0000480
GO:0003723
GO:0005515
GO:0005634
GO:0005654
GO:0005730
GO:0006364
GO:0030686
GO:0032040
GO:0034511
GO:0042254
GO:0042274
GO:0043226
HMNXSV003002058
HMNXSV003009526
HMNXSV003014350
Hs2.375815.1.S1_3p_at
ILMN_2177413
PH_hs_0031548
PH_hs_0036735
TC16000054.hg
TC16000055.hg
U02609_at
g12803114_3p_s_at
g4325313_3p_a_at
Participates
as a component of
UTPB complex [nucleoplasm] (Homo sapiens)
Inferred To
Tbl3 [nucleoplasm]
(Mus musculus)
Tbl3 [nucleoplasm]
(Rattus norvegicus)
utp13 [nucleoplasm]
(Dictyostelium discoideum)
utp13 [nucleoplasm]
(Schizosaccharomyces pombe)
Dmel\CG1671 [nucleoplasm]
(Drosophila melanogaster)
TBL3 [nucleoplasm]
(Bos taurus)
TBL3 [nucleoplasm]
(Caenorhabditis elegans)
TBL3 [nucleoplasm]
(Canis familiaris)
TBL3 [nucleoplasm]
(Gallus gallus)
TBL3 [nucleoplasm]
(Plasmodium falciparum)
TBL3 [nucleoplasm]
(Sus scrofa)
UTP13 [nucleoplasm]
(Saccharomyces cerevisiae)
Cross References
RefSeq
NP_006444.2
OpenTargets
ENSG00000183751
HPA
ENSG00000183751-TBL3
GeneCards
Q12788
Ensembl
ENSP00000454836
,
ENSG00000183751
,
ENST00000568546
PRO
Q12788
Pharos - Targets
Q12788
PDB
7MQA
,
7MQ8
,
7MQ9
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P06748 NPM1
11
monoSUMO1-K263-NPM1 [nucleoplasm]
(R-HSA-4086039)
polySUMO2,3-K263-NPM1 [nucleoplasm]
(R-HSA-4086056)
NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm]
(R-HSA-9725010)
NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol]
(R-HSA-9730703)
NPM1(1-117)-ALK(1068-1620) fusion [cytosol]
(R-HSA-9730697)
NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol]
(R-HSA-9699861)
NPM1(1-117)-ALK(1058-1620) fusion [cytosol]
(R-HSA-9699834)
NPM1 [granular component]
(R-HSA-9017702)
NPM1 [nucleoplasm]
(R-HSA-606320)
NPM1 [cytosol]
(R-HSA-3008211)
p-S4-NPM1 [cytosol]
(R-HSA-6801679)
0.615
3
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