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Ub-HIST1H2BD [nucleoplasm]
Stable Identifier
R-HSA-6782546
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
HIST1H2BD, Histone H2B.b
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Deubiquitination (Homo sapiens)
Ub-specific processing proteases (Homo sapiens)
USP3,SAGA deubiquitinate Histone H2A,H2B (Homo sapiens)
USP3,SAGA:Ub-histone H2A, Ub-histone H2B [nucleoplasm] (Homo sapiens)
Ub-histone H2A, Ub-histone H2B [nucleoplasm] (Homo sapiens)
Ub-histone H2B [nucleoplasm] (Homo sapiens)
Ub-histone HIST1H2B [nucleoplasm] (Homo sapiens)
Ub-HIST1H2BD [nucleoplasm] (Homo sapiens)
USP49 deubiquitinates H2B (Homo sapiens)
USP49:Ub-histone H2B [nucleoplasm] (Homo sapiens)
Ub-histone H2B [nucleoplasm] (Homo sapiens)
Ub-histone HIST1H2B [nucleoplasm] (Homo sapiens)
Ub-HIST1H2BD [nucleoplasm] (Homo sapiens)
Protein ubiquitination (Homo sapiens)
E3 ubiquitin ligases ubiquitinate target proteins (Homo sapiens)
RNF20:RNF40 monoubiquitinates Histone H2B (Homo sapiens)
Ub-histone HIST1H2B [nucleoplasm] (Homo sapiens)
Ub-HIST1H2BD [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P58876 H2BC5
Gene Names
H2BC5, H2BFB, HIRIP2, HIST1H2BD
Chain
initiator methionine:, chain:2-126
Reference Genes
BioGPS Gene:3017 H2BC5
COSMIC (genes):HIST1H2BD H2BC5
CTD Gene:3017 H2BC4
dbSNP Gene:3017 H2BC5
ENSEMBL:ENSG00000158373 HIST1H2BD
HGNC:4747 H2BC5
KEGG:hsa:3017 H2BC5
Monarch:3017 H2BC5
NCBI Gene:3017 H2BC5
OMIM:602799 H2BC5
UCSC:P58876 H2BC5
Reference Transcript
RefSeq:NM_138720.2 H2BC5
RefSeq:NM_021063.3 H2BC5
RefSeq:XM_005249039.3 H2BC5
Other Identifiers
11724021_at
11728152_a_at
11728153_x_at
17005573
209911_PM_x_at
209911_x_at
222067_PM_x_at
222067_x_at
2899178
2899179
2899193
2947034
3017
38576_at
8117382
88155_at
ADDON002904.hg
ADDON002918.hg
A_24_P146211
GE63182
GO:0000786
GO:0003674
GO:0003677
GO:0005198
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005829
GO:0030527
GO:0043226
GO:0043229
GO:0046982
GO:0070062
HMNXSV003000583
HMNXSV003001089
Hs.180779.1.S1_3p_at
ILMN_1651496
ILMN_1758623
ILMN_1777405
PH_hs_0010698
TC06000169.hg
g12803984_3p_at
g12803984_3p_x_at
Participates
as a member of
Ub-histone HIST1H2B [nucleoplasm] (Homo sapiens)
Other forms of this molecule
AcK-HIST1H2BD [nucleoplasm]
HIST1H2BD [extracellular region]
AcK16-HIST1H2BD [nucleoplasm]
AcK6-HIST1H2BD [nucleoplasm]
AcK21-HIST1H2BD [nucleoplasm]
AcK13-HIST1H2BD [nucleoplasm]
Ub-121-HIST1H2BD [nucleoplasm]
HIST1H2BD [nucleoplasm]
Inferred To
H2Bv2 [nucleoplasm]
(Dictyostelium discoideum)
htb1 [nucleoplasm]
(Schizosaccharomyces pombe)
H2bc9 [nucleoplasm]
(Mus musculus)
Homologues of Ub-HIST1H2BB [nucleoplasm]
(Dictyostelium discoideum)
Homologues of Ub-HIST1H2BB [nucleoplasm]
(Saccharomyces cerevisiae)
HIST1H2B5L [nucleoplasm]
(Gallus gallus)
Ub-HIST1H2BC [nucleoplasm]
(Danio rerio)
H2B-V [nucleoplasm]
(Gallus gallus)
Ub-HIST1H2BD [nucleoplasm]
(Bos taurus)
Ub-HIST1H2BD [nucleoplasm]
(Canis familiaris)
Ub-HIST1H2BD [nucleoplasm]
(Sus scrofa)
H2Bv3 [nucleoplasm]
(Dictyostelium discoideum)
H2B-VII [nucleoplasm]
(Gallus gallus)
H2B-I [nucleoplasm]
(Gallus gallus)
HTB2 [nucleoplasm]
(Saccharomyces cerevisiae)
H2Bv1 [nucleoplasm]
(Dictyostelium discoideum)
H2B-VIII [nucleoplasm]
(Gallus gallus)
His2B [nucleoplasm]
(Drosophila melanogaster)
Homologues of Ub-HIST1H2BC [nucleoplasm]
(Danio rerio)
Homologues of Ub-HIST1H2BC [nucleoplasm]
(Gallus gallus)
Homologues of Ub-HIST1H2BC [nucleoplasm]
(Xenopus tropicalis)
h2bc11 [nucleoplasm]
(Xenopus tropicalis)
si:ch211-113a14.22 [nucleoplasm]
(Danio rerio)
LOC100498553 [nucleoplasm]
(Xenopus tropicalis)
LOC116411635 [nucleoplasm]
(Xenopus tropicalis)
hist2h2l [nucleoplasm]
(Danio rerio)
ENSRNOG00000064540 [nucleoplasm]
(Rattus norvegicus)
HTB1 [nucleoplasm]
(Saccharomyces cerevisiae)
LOC570661 [nucleoplasm]
(Danio rerio)
h2bc21 [nucleoplasm]
(Xenopus tropicalis)
Modified Residues
Name
ubiquitinylated lysine (monoUb [nucleoplasm]) at 120
Coordinate
120
Modification
monoUb [nucleoplasm]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
NP_066407.1
,
NP_619790.1
,
XP_005249096.1
ENSEMBL
ENST00000377777
,
ENSP00000367008
,
ENSP00000289316
,
ENST00000289316
,
ENSG00000158373
OpenTargets
ENSG00000158373
GeneCards
H2BC5
HPA
ENSG00000158373-H2BC5
PRO
P58876
Pharos - Targets
P58876
GlyGen
P58876
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P16104 H2AFX
7
H2AFX [nucleoplasm]
(R-HSA-56151)
p-Y143-H2AFX [nucleoplasm]
(R-HSA-5683942)
p-S140,Y143-H2AFX [nucleoplasm]
(R-HSA-5683953)
p-S140-H2AFX [nucleoplasm]
(R-HSA-75170)
K63PolyUb-K14,K16,p-S140-H2AFX [nucleoplasm]
(R-HSA-5682847)
H2AFX [extracellular region]
(R-HSA-977583)
Me2sR4-H2AFX [nucleoplasm]
(R-HSA-5218317)
0.669
3
UniProt:Q01831 XPC
5
XPC [nucleoplasm]
(R-HSA-67441)
Ub-XPC [nucleoplasm]
(R-HSA-6782944)
Ub,SUMO-XPC [nucleoplasm]
(R-HSA-6790460)
Ub,SUMO,K63polyUb-XPC [nucleoplasm]
(R-HSA-6790522)
monoSUMO1-K655-XPC [nucleoplasm]
(R-HSA-4570458)
0.527
3
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