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MYO10 [cytosol]
Stable Identifier
R-HSA-593679
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Myosin-X, Myo X, Myosin-10
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
Netrin-1 signaling (Homo sapiens)
Myosin-X binds DCC/Neogenin (Homo sapiens)
DCC,NEO1:MYO10 [plasma membrane] (Homo sapiens)
MYO10 [cytosol] (Homo sapiens)
MYO10 [cytosol] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Parasitic Infection Pathways (Homo sapiens)
Leishmania infection (Homo sapiens)
Parasite infection (Homo sapiens)
Leishmania phagocytosis (Homo sapiens)
FCGR3A-mediated phagocytosis (Homo sapiens)
Extension of pseudopodia by myosin-X in a PI3K dependent manner (Homo sapiens)
Actin filament bound Myosin-X [plasma membrane] (Homo sapiens)
Myosin-X dimer [cytosol] (Homo sapiens)
MYO10 [cytosol] (Homo sapiens)
Myosin-X dimer [cytosol] (Homo sapiens)
MYO10 [cytosol] (Homo sapiens)
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Fcgamma receptor (FCGR) dependent phagocytosis (Homo sapiens)
Regulation of actin dynamics for phagocytic cup formation (Homo sapiens)
Extension of pseudopodia by myosin-X in a PI3K dependent manner (Homo sapiens)
Actin filament bound Myosin-X [plasma membrane] (Homo sapiens)
Myosin-X dimer [cytosol] (Homo sapiens)
MYO10 [cytosol] (Homo sapiens)
Myosin-X dimer [cytosol] (Homo sapiens)
MYO10 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9HD67 MYO10
Gene Names
MYO10, KIAA0799
Chain
chain:1-2058
Reference Genes
BioGPS Gene:4651 MYO10
COSMIC (genes):MYO10 MYO10
CTD Gene:4651 MYO10
dbSNP Gene:4651 MYO10
ENSEMBL:ENSG00000145555 MYO10
HGNC:7593 MYO10
KEGG:hsa:4651 MYO10
Monarch:4651 MYO10
NCBI Gene:4651 MYO10
OMIM:601481 MYO10
UCSC:Q9HD67 MYO10
Reference Transcript
RefSeq:XM_005248307.2 MYO10
RefSeq:XM_011514046.2 MYO10
RefSeq:NM_012334.2 MYO10
Other Identifiers
11742414_x_at
11744346_a_at
11744347_a_at
11746132_a_at
11759661_at
1554026_PM_a_at
1554026_a_at
16994618
201976_PM_s_at
201976_s_at
216222_PM_s_at
216222_s_at
236718_PM_at
236718_at
244350_PM_at
244350_at
2850077
2850078
2850079
2850080
2850081
2850082
2850084
2850085
2850086
2850087
2850088
2850089
2850090
2850092
2850093
2850096
2850097
2850098
2850100
2850105
2850106
2850107
2850108
2850109
2850110
2850111
2850112
2850113
2850114
2850116
2850117
2850118
2850119
2850132
2850138
2850143
2850145
2850146
2850147
2850148
2850149
2850150
2850151
2850154
2850159
2850160
2850161
2850163
2850164
2850166
2850169
2850176
2850177
2850179
2850195
2850204
2850210
2850211
2850212
2850213
2850231
2850233
2850235
2850237
2850239
35362_at
4651
53130_at
70851_at
79582_at
8111153
A_23_P7596
A_24_P46357
A_24_P924183
A_33_P3341424
GE55001
GE813126
GO:0000146
GO:0001726
GO:0003774
GO:0003779
GO:0005515
GO:0005516
GO:0005524
GO:0005547
GO:0005730
GO:0005737
GO:0005829
GO:0005856
GO:0005886
GO:0005938
GO:0007165
GO:0008092
GO:0008289
GO:0008360
GO:0016459
GO:0022409
GO:0030027
GO:0030175
GO:0030507
GO:0030705
GO:0031527
GO:0032433
GO:0042995
GO:0043005
GO:0043025
GO:0043226
GO:0051015
GO:0051489
GO:0060002
GO:0140657
HMNXSV003052312
Hs.143764.0.A1_3p_at
Hs.43334.0.A1_3p_at
Hs.61638.1.S1_3p_a_at
Hs2.209670.1.S1_3p_s_at
ILMN_2232712
PH_hs_0003156
PH_hs_0003919
TC05001184.hg
g11037056_3p_a_at
Participates
as a component of
DCC,NEO1:MYO10 [plasma membrane] (Homo sapiens)
Myosin-X dimer [cytosol] (Homo sapiens)
as an input of
Myosin-X binds DCC/Neogenin (Homo sapiens)
Inferred To
MYO10 [cytosol]
(Bos taurus)
MYO10 [cytosol]
(Canis familiaris)
MYO10 [cytosol]
(Mus musculus)
MYO10 [cytosol]
(Rattus norvegicus)
MYO10 [cytosol]
(Sus scrofa)
Cross References
RefSeq
XP_005248364.1
,
NP_036466.2
,
XP_011512348.1
ENSEMBL
ENST00000507288
,
ENSP00000421280
,
ENST00000513610
,
ENSP00000426664
OpenTargets
ENSG00000145555
HPA
ENSG00000145555-MYO10
PRO
Q9HD67
Pharos - Targets
Q9HD67
HMDB Protein
HMDBP14136
PDB
3AU5
,
5KG8
,
3AU4
,
3PZD
,
5I0I
,
5I0H
,
2LW9
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P27482 CALL3
0.676
3
UniProt:P43146 DCC
4
p-Y1420-DCC [plasma membrane]
(R-HSA-374552)
DCC(1291-1447) [cytosol]
(R-HSA-373629)
DCC [plasma membrane]
(R-HSA-197560)
DCC(26-1290) [plasma membrane]
(R-HSA-373627)
0.65
7
UniProt:P62158 CALM
0.558
2
UniProt:P18084 ITGB5
2
ITGB5 [phagocytic vesicle]
(R-HSA-1236749)
ITGB5 [plasma membrane]
(R-HSA-215948)
0.544
2
UniProt:Q63155 Dcc
5
DCC [plasma membrane]
(R-RNO-421662)
phospho-Dcc [plasma membrane]
(R-RNO-374552)
Dcc [cytosol]
(R-RNO-373629)
Dcc [plasma membrane]
(R-RNO-197560)
Dcc [plasma membrane]
(R-RNO-373627)
0.544
3
UniProt:Q96JJ6 JPH4
0.527
2
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